Additivity of mutational effects in proteins.

Abstract

Study holds ProTherm entries: 4181, 4182, 4183 Extra Details: additivity; mutational effects; protein stability

Submission Details

ID: z6NUPnhi3

Submitter: Connie Wang

Submission Date: April 24, 2018, 8:24 p.m.

Version: 1

Publication Details
Wells JA,Biochemistry (1990) Additivity of mutational effects in proteins. PMID:2271534
Additional Information

Study Summary

Number of data points 3
Proteins Tissue-type plasminogen activator ; Tissue-type plasminogen activator
Unique complexes 3
Assays/Quantities/Protocols Experimental Assay: dG
Libraries Mutations for sequence SEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST

Structure view and single mutant data analysis

Study data

No weblogo for data of varying length.
Colors: D E R H K S T N Q A V I L M F Y W C G P
 

Data Distribution

Studies with similar sequences (approximate matches)

Correlation with other assays (exact sequence matches)


Relevant UniProtKB Entries

Percent Identity Matching Chains Protein Accession Entry Name
100.0 Tissue-type plasminogen activator P00750 TPA_HUMAN
97.9 Tissue-type plasminogen activator Q5R8J0 TPA_PONAB