Remarkable thermal stability of doubly intramolecularly cross-linked hen lysosymeProtein engineering (2000), 3, 193-196
Abstract
Study holds ProTherm entries: 8200 Extra Details: cross-linking; differential scanning calorimetry;,lysozyme; thermal stability
Submission Details
ID: qqF7Pp4i
Submitter: Connie Wang
Submission Date: April 24, 2018, 8:35 p.m.
Version: 1
Publication Details
Ueda T;Masumoto K;Ishibashi R;So T;Imoto T,Protein Eng. (2000) Remarkable thermal stability of doubly intramolecularly cross-linked hen lysosymeProtein engineering (2000), 3, 193-196 PMID:10964991Additional Information
Study Summary
| Number of data points | 1 |
| Proteins | Lysozyme C ; Lysozyme C |
| Unique complexes | 1 |
| Assays/Quantities/Protocols | Experimental Assay: Tm |
| Libraries | Mutations for sequence KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL |
Structure view and single mutant data analysis
Study data
| Colors: | D | E | R | H | K | S | T | N | Q | A | V | I | L | M | F | Y | W | C | G | P |
|---|
Data Distribution
Studies with similar sequences (approximate matches)
Correlation with other assays (exact sequence matches)
Relevant PDB Entries
| Structure ID | Release Date | Resolution | Structure Title |
|---|---|---|---|
| 2IHL | 1993-06-29T00:00:00+0000 | 1.4 | LYSOZYME (E.C.3.2.1.17) (JAPANESE QUAIL) |
| 1JHL | 1993-05-04T00:00:00+0000 | 2.4 | THREE-DIMENSIONAL STRUCTURE OF A HETEROCLITIC ANTIGEN-ANTIBODY CROSS-REACTION COMPLEX |
| 1GHL | 1993-05-04T00:00:00+0000 | 2.1 | THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES |
| 1FBI | 1995-01-19T00:00:00+0000 | 3.0 | CRYSTAL STRUCTURE OF A CROSS-REACTION COMPLEX BETWEEN FAB F9.13.7 AND GUINEA-FOWL LYSOZYME |
| 1HHL | 1993-05-04T00:00:00+0000 | 1.9 | THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES |
| 1BQL | 1995-02-03T00:00:00+0000 | 2.6 | STRUCTURE OF AN ANTI-HEL FAB FRAGMENT COMPLEXED WITH BOBWHITE QUAIL LYSOZYME |
| 1DKJ | 1996-01-10T00:00:00+0000 | 2.0 | BOBWHITE QUAIL LYSOZYME |
| 1DKK | 1996-01-10T00:00:00+0000 | 1.9 | BOBWHITE QUAIL LYSOZYME WITH NITRATE |
| 1JTP | 2001-08-21T00:00:00+0000 | 1.9 | Degenerate interfaces in antigen-antibody complexes |
| 1UAC | 2003-03-08T00:00:00+0000 | 1.7 | Crystal Structure of HYHEL-10 FV MUTANT SFSF Complexed with TURKEY WHITE LYSOZYME |
Relevant UniProtKB Entries
| Percent Identity | Matching Chains | Protein | Accession | Entry Name |
|---|---|---|---|---|
| 92.3 | Lysozyme C | P49663 | LYSC_PHAVE | |
| 93.0 | Lysozyme C | P81711 | LYSC_SYRSO | |
| 93.2 | Lysozyme C | P00702 | LYSC_PHACO | |
| 94.6 | Lysozyme C | P24533 | LYSC_SYRRE | |
| 93.0 | Lysozyme C | P24364 | LYSC_LOPLE | |
| 92.2 | Lysozyme C | P00704 | LYSC_NUMME | |
| 95.2 | Lysozyme C | P00703 | LYSC_MELGA | |
| 95.3 | Lysozyme C | Q7LZT2 | LYSC_TRATE | |
| 95.3 | Lysozyme C | P22910 | LYSC_CHRAM | |
| 96.1 | Lysozyme C | P19849 | LYSC_PAVCR | |
| 95.3 | Lysozyme C | P00701 | LYSC_COTJA | |
| 96.1 | Lysozyme C | Q7LZI3 | LYSC_TRASA | |
| 96.9 | Lysozyme C | Q7LZP9 | LYSC_LOPIM | |
| 96.9 | Lysozyme C | Q7LZQ0 | LYSC_CATWA | |
| 96.9 | Lysozyme C | P00699 | LYSC_CALCC | |
| 96.9 | Lysozyme C | P00700 | LYSC_COLVI | |
| 100.0 | Lysozyme C | P00698 | LYSC_CHICK |