Myoglobins from three small placental mammals and one small marsupial were isolated from cardiac or skeletal muscle. The conformational free energies of these four myoglobins were estimated from guanidinium chloride unfolding data at pH 8 and 25 degrees. The myoglobins from rat and rabbit are more stable than that of the most stable myoglobin previously studied, that of the sperm whale. In addition, these two myoglobins unfold with greater cooperativity than previously characterized myoglobins. The data obtained herein demonstrate unequivocally for the first time that the stability of homeotherm myoglobins correlates with neither the size of the organism nor its metabolic rate. Study holds ProTherm entries: 10112, 10113, 10114, 10115 Extra Details: denaturation; guanidinium chloride; mammals;,myoglobin
ID: qf2FpHPv
Submitter: Connie Wang
Submission Date: April 24, 2018, 8:39 p.m.
Version: 1
Colors: | D | E | R | H | K | S | T | N | Q | A | V | I | L | M | F | Y | W | C | G | P |
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Percent Identity | Matching Chains | Protein | Accession | Entry Name |
---|---|---|---|---|
100.0 | Myoglobin | P02193 | MYG_DIDVI | |
92.2 | Myoglobin | P02163 | MYG_ROUAE | |
90.9 | Myoglobin | P68086 | MYG_ERYPA | |
90.9 | Myoglobin | P68084 | MYG_PAPAN | |
90.9 | Myoglobin | P68085 | MYG_SEMEN | |
90.3 | Myoglobin | P02144 | MYG_HUMAN | |
90.9 | Myoglobin | P20856 | MYG_CTEGU | |
90.3 | Myoglobin | P02150 | MYG_MACFA | |
92.9 | Myoglobin | P02189 | MYG_PIG | |
100.0 | Myoglobin | P02170 | MYG_RABIT | |
92.9 | Myoglobin | P02165 | MYG_TUPGL | |
90.3 | Myoglobin | P02181 | MYG_INIGE | |
94.2 | Myoglobin | P11343 | MYG_LUTLU | |
90.9 | Myoglobin | P02166 | MYG_PERPO | |
90.3 | Myoglobin | P02145 | MYG_PANTR | |
100.0 | Myoglobin | P04248 | MYG_SPAEH | |
93.5 | Myoglobin | P02171 | MYG_OCHPR | |
90.3 | Myoglobin | P02167 | MYG_NYCCO | |
92.9 | Myoglobin | P04249 | MYG_PROGU | |
92.2 | Myoglobin | Q6PL31 | MYG_OCHCU | |
91.6 | Myoglobin | C0HJQ9 | MYG_HYSCR | |
91.6 | Myoglobin | P04250 | MYG_LAGMA | |
90.3 | Myoglobin | P02164 | MYG_ORYAF | |
90.3 | Myoglobin | P02156 | MYG_ERIEU | |
90.3 | Myoglobin | P02157 | MYG_MELME | |
90.3 | Myoglobin | C0HKB7 | MYG_SCIVU |