Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules.


Abstract

A series of 24 mutants was made in the buried core of chicken lysozyme at positions 40, 55, and 91. The midpoint temperature of thermal denaturation transition (Tm) values of these core constructs range from 60.9 to 77.3 degrees C, extending an earlier, more limited investigation on thermostability. The Tm values of variants containing conservative replacements for the wild type (WT) (Thr 40-Ile 55-Ser 91) triplet are linearly correlated with hydrophobicity (r = 0.81) and, to a lesser degree, with combined side-chain volume (r = 0.75). The X-ray structures of the S91A (1.9 A) and I55L/S91T/D101S (1.7 A) mutants are presented. The former amino acid change is found in duck and mammalian lysozymes, and the latter contains the most thermostable core triplet. A network of four conserved, buried water molecules is associated with the core. It is postulated that these water molecules significantly influence the mutational tolerance at the individual triplet positions. The pH dependence of Tm for the S91D mutant was compared with that of WT enzyme. The pKa of S91D is 1.2 units higher in the native than in the denatured state, corresponding to delta delta G298 = 1.7 kcal/mol. This is a low value for charge burial and likely reflects the moderating influence of the buried water molecules or a conformational change. Thermal and chemical denaturation and far UV CD spectroscopy were used to characterize the in vitro properties of I55T. This variant, which buries a hydroxyl group, has similar properties to those of the human amyloidogenic variant I56T. Study holds ProTherm entries: 1795, 1796, 1797, 1798, 1799, 1800, 1801, 1802, 1803, 1804, 1805, 1806, 1807, 1808, 1809, 1810, 1811, 1812, 1813, 1814, 1815, 1816, 1817, 1818, 1819, 1820, 13890, 13891, 13892, 13893, 13894, 13895, 13896, 13897, 13898, 13899, 13900, 13901, 13902, 13903, 13904, 13905, 13906, 13907, 13908, 13909, 13910, 13911, 13912, 13913 Extra Details: buried water; chicken lysozyme; hydrophobicity; internal packing;,site-directed mutagenesis; X-ray structure; thermal stability;

Submission Details

ID: anQDUU3h3

Submitter: Connie Wang

Submission Date: April 24, 2018, 8:17 p.m.

Version: 1

Publication Details
Shih P;Holland DR;Kirsch JF,Protein Sci. (1995) Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules. PMID:8535241
Additional Information

Structure view and single mutant data analysis

Study data

No weblogo for data of varying length.
Colors: D E R H K S T N Q A V I L M F Y W C G P
 

Data Distribution

Studies with similar sequences (approximate matches)

Correlation with other assays (exact sequence matches)


Relevant PDB Entries

Structure ID Release Date Resolution Structure Title
2HS7 2006-08-29 Multipattern rietveld refinement with protein powder data: An approach to higher resolution
1SF4 2004-03-02 BINDING OF N,N'-DIACETYLCHITOBIOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY
2A6U 2006-01-03 pH evolution of tetragonal HEWL at 4 degrees Celcius.
1SF6 2004-03-02 BINDING OF N,N',N'-TRIACETYLCHITOTRIOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY
1GXX 2003-03-27 Solution structure of lysozyme at low and high pressure
1GXV 2003-03-27 Solution structure of lysozyme at low and high pressure
1SFG 2004-03-02 BINDING OF HEXA-N-ACETYLCHITOHEXAOSE: A POWDER DIFFRACTION STUDY
2HS9 2006-08-08 Multipattern Rietveld refinement with protein powder data: An approach to higher resolution
1SF7 2004-03-02 BINDING OF TETRA-N-ACETYLCHITOTETRAOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY
2HSO 2006-08-29 Multipattern rietveld refinement with protein powder data: An approach to higher resolution
1E8L 2000-10-09 NMR solution structure of hen lysozyme
1SFB 2004-03-02 BINDING OF PENTA-N-ACETYLCHITOPENTAOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY
2VB1 2007-09-18 0.65 HEWL at 0.65 angstrom resolution
3LZT 1998-03-25 0.93 REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC RESOLUTION
1IEE 2001-08-08 0.94 STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME AT 0.94 A FROM CRYSTALS GROWN BY THE COUNTER-DIFFUSION METHOD
4LZT 1998-04-01 0.95 ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW LYSOZYME AT 295K
3WL2 2014-11-12 0.96 Monoclinic Lysozyme at 0.96 A resolution
6F1O 2018-05-09 0.96 Orthorhombic Lysozyme crystallized at 298 K and pH 4.5
5HMV 2016-05-18 0.98 Re refinement of 4mwk.
4YEO 2015-03-04 0.98 Triclinic HEWL co-crystallised with cisplatin, studied at a data collection temperature of 150K - new refinement
4B4E 2012-08-22 1.0 1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol
5HQ1 2016-05-18 1.0 Comment on S. W. M. Tanley and J. R. Helliwell Structural dynamics of cisplatin binding to histidine in a protein Struct. Dyn. 1, 034701 (2014) regarding the refinement of 4mwk, 4mwm, 4mwn and 4oxe and the method we have adopted.
5LXW 2016-10-05 1.0 Atomic resolution X-ray crystal structure of cisplatin bound to hen egg white lysozyme stored for 5 years on the shelf
6RO3 2019-06-19 1.03 2Yr-X: Lysozyme with Re Cluster 2 year on shelf
6RT3 2019-06-05 1.05 Native tetragonal lysozyme - synchrotron data
3AJN 2011-02-16 1.05 Structural basis of glycine amide on suppression of protein aggregation by high resolution X-ray analysis
4NG8 2014-05-28 1.09 Dialyzed HEW lysozyme batch crystallized in 1.9 M CsCl and collected at 100 K.
4AXT 2012-10-24 1.1 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL, Control Experiment
5K2Q 2017-05-31 1.1 Lysozyme with nano particles
5MYY 2017-07-12 1.1 Hen Egg-White Lysozyme (HEWL) cocrystallized in the presence of Cadmium sulphate
1LKS 1998-04-29 1.1 HEN EGG WHITE LYSOZYME NITRATE
6F1R 2018-05-09 1.1 Tetragonal Lysozyme crystallized at 298 K and pH 4.5 with phosphate bound: control experiment
4B0D 2012-10-24 1.1 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL
4NGJ 2014-05-28 1.1 Dialyzed HEW lysozyme batch crystallized in 1.0 M RbCl and collected at 100 K
1JSE 1998-04-29 1.12 FULL-MATRIX LEAST-SQUARES REFINEMENT OF TURKEY LYSOZYME
6F1P 2018-05-09 1.12 Tetragonal Lysozyme crystallized at 298 K and pH 4.5 with phosphate bound
1WTN 2004-12-14 1.13 The structure of HEW Lysozyme Orthorhombic Crystal Growth under a High Magnetic Field
6A10 2019-02-20 1.13 Crystal structure of hen egg white lysozyme crystallized by ammonium sulfate
5IDD 2016-05-18 1.13 Comment on S. W. M. Tanley and J. R. Helliwell Structural dynamics of cisplatin binding to histidine in a protein Struct. Dyn. 1, 034701 (2014) regarding the refinement of 4mwk, 4mwm, 4mwn and 4oxe and the method we have adopted.
1V7T 2004-04-06 1.13 Triclinic lysozyme with low solvent content obtained by phase transition
6G8A 2018-08-01 1.14 Lysozyme solved by Native SAD from a dataset collected in 5 seconds at 1 A wavelength with JUNGFRAU detector
1V7S 2004-04-06 1.14 Triclinic hen lysozyme crystallized at 313K from a D2O solution
2Z18 2008-03-18 1.15 Phase transition of monoclinic lysozyme crystal soaked in a 10% NaCl solution
2Z19 2008-03-18 1.15 Phase transition of monoclinic lysozyme crystal soaked in a saturated NaCl solution
5F14 2016-02-24 1.15 Structure of native hen egg-white lysozyme
2Z12 2008-03-18 1.15 Structure of the transformed monoclinic lysozyme by controlled dehydration
5IEL 2017-03-08 1.15 Structure of Lysozyme labeled with fluorescein isothiocyanate (FITC) at 1.15 Angstroms resolution
4B49 2012-08-22 1.15 1.15 A Structure of Lysozyme Crystallized without 2-methyl-2,4- pentanediol
2D4K 2006-07-11 1.15 Monoclinic hen egg-white lysozyme crystallized at 313K
2D4I 2006-07-11 1.16 Monoclinic hen egg-white lysozyme crystallized at pH4.5 form heavy water solution
2D4J 2006-07-11 1.16 Transformed monoclinic crystal of hen egg-white lysozyme from a heavy water solution
3ATO 2012-03-07 1.17 Glycine ethyl ester shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation
3ATN 2012-03-07 1.17 Glycine ethyl ester shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation
2ZYP 2009-02-17 1.18 X-ray structure of hen egg-white lysozyme with poly(allyl amine)
4HP0 2013-01-16 1.19 Crystal Structure of Hen Egg White Lysozyme in complex with GN3-M
4HPI 2013-01-16 1.19 Crystal Structure of Hen Egg White Lysozyme complex with GN2-M
1LJN 2002-06-05 1.19 Crystal Structure of Tuekey Egg Lysozyme Complex with Di-N-acetylchitobiose at 1.19A Resolution
5F16 2016-02-24 1.2 CTA-modified hen egg-white lysozyme
3D9A 2008-06-10 1.2 High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme
4H9C 2013-05-15 1.2 Radiation damage study of lysozyme - 0.77 MGy
4HTK 2013-05-15 1.2 Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 2.17 x 10e+12 X-ray photons
4H94 2013-05-15 1.2 Radiation damage in lysozyme - 0.56 MGy
6FSJ 2018-05-02 1.2 Crystal structure of TCE-treated Lysozyme
5KXY 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 8
4N8Z 2013-10-30 1.2 In situ lysozyme crystallized on a MiTeGen micromesh with benzamidine ligand
5KY1 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 10
4B4I 2012-08-22 1.2 1.20 A Structure of Lysozyme Crystallized with (S)-2-methyl-2,4- pentanediol
3AGI 2011-03-23 1.2 High resolution X-ray analysis of Arg-lysozyme complex in the presence of 500 mM Arg
4H8X 2013-05-15 1.2 Radiation damage study of lysozyme - 0.07 MGy
4H9A 2013-05-15 1.2 Radiation damage study of lysozyme - 0.63 MGy
4H9I 2013-05-15 1.2 Radiation damage study of lysozyme - 1.05 MGy
5KXN 2016-09-07 1.2 Hen Egg White Lysozyme at 100K, Data set 4
2HUB 2007-07-24 1.2 Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5
5KXW 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 6
5FST 2016-10-26 1.2 Structure of lysozyme prepared by the 'soak-and-freeze' method under 100 bar of krypton pressure
5KJ9 2016-07-06 1.2 Anticancer activity of Ru- and Os(arene) compounds of a maleimide-functionalized bioactive pyridinecarbothioamide ligand
5KXS 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 4
5KXL 2016-09-07 1.2 Hen Egg White Lysozyme at 100K, Data set 2
5KXM 2016-09-07 1.2 Hen Egg White Lysozyme at 100K, Data set 3
4H91 2013-05-15 1.2 Radiation damage study of lysozyme - 0.35 MGy
5KXR 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 3
1QIO 2001-04-11 1.2 SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE CAUSED BY INTENSE SYNCHROTRON RADIATION TO HEN EGG WHITE LYSOZYME
5KXK 2016-09-07 1.2 Hen Egg White Lysozyme at 100K, Data set 1
5KXO 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 1
6F9Y 2018-05-09 1.2 Lysozyme crystallized in presence of 10 mM lithium sulphate at pH 4.5
4H9B 2013-05-15 1.2 Radiation damage study of lysozyme - 0.70 MGy
4H8Z 2013-05-15 1.2 Radiation damage study of lysozyme - 0.21 MGy
5KXZ 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 9
4H9H 2013-05-15 1.2 Radiation damage study of lysozyme - 0.98 MGy
4H90 2013-05-15 1.2 Radiation damage study of lysozyme - 0.28 MGy
4H93 2013-05-15 1.2 Radiation damage study of lysozyme - 0.49 MGy
5KXP 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 2
5V4G 2017-04-05 1.2 Ruthenium(II)(cymene)(chlorido)2-lysozyme adduct with two binding sites
6F9Z 2018-05-09 1.2 Lysozyme crystallized in presence of 5 mM ammonium sulphate at pH 4.5
4H8Y 2013-05-15 1.2 Radiation damage study of lysozyme- 0.14 MGy
5KXX 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 7
5EBH 2016-04-13 1.2 Crystal Structure HEW Lysozyme processed with the CrystalDirect automated mounting and cryo-cooling technology
4H92 2013-05-15 1.2 Radiation damage study of lysozyme- 0.42 MGy
6F2I 2018-10-03 1.2 Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4
4H9E 2013-05-15 1.2 Radiation damage study of lysozyme - 0.84 MGy
5KXT 2016-09-07 1.2 Hen Egg White Lysozyme at 278K, Data set 5
4H9F 2013-05-15 1.2 Radiation damage study of lysozyme - 0.91 MGy
4LYB 2015-02-25 1.21 CdS within a lysoyzme single crystal
4BAP 2012-11-14 1.21 Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethylcholinetriazoledipicolinate complex at 1.21 A resolution.
5V4H 2017-04-05 1.22 Ruthenium(II)(cymene)(chlorido)2-lysozyme adduct formed when ruthenium(II)(cymene)(bromido)2 underwent ligand exchange, resulting in one binding site
5DLA 2015-09-16 1.22 Structure of Tetragonal Lysozyme solved by UWO Students
4RDS 2015-01-14 1.23 Lysozyme crystallized with red food coloring dye
6GNL 2018-10-31 1.23 Zr(IV)-substituted Keggin directly binding to the side chain of Hen Egg-White Lysozyme (HEWL)
6BO1 2018-05-16 1.24 Mono-adduct formed after 3 days in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL
5K2P 2017-05-31 1.24 Crystal structure of lysozyme
6F9X 2018-05-09 1.25 Lysozyme crystallized in presence of 100 mM lithium sulphate at pH 4.5
2D6B 2005-11-29 1.25 Novel Bromate Species trapped within a Protein Crystal
4XAD 2014-12-31 1.25 Crystal structure of hen egg white lysozyme in complex with Galf-GlcNAc
4B4J 2012-08-22 1.25 1.25 A Structure of Lysozyme Crystallized with (RS)-2-methyl-2,4- pentanediol
5B5J 2017-06-28 1.26 Hen egg white lysozyme with boron tracedrug UTX-97
5NBJ 2017-05-10 1.27 DLS Tetragonal - ReHEWL
4C3W 2014-07-09 1.28 Vanadium(IV)-Picolinate Complexed with Lysozyme
2XBR 2010-11-24 1.29 Raman crystallography of Hen White Egg Lysozyme - Low X-ray dose (0.2 MGy)
6FA0 2018-05-09 1.3 Lysozyme crystallized in presence of 100 mM ammonium sulphate at pH 4.5
6F1L 2018-05-09 1.3 Lysozyme crystallized in presence of 100 mM sodium phosphate at pH 4.5
3P64 2011-02-09 1.3 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme
135L 1993-10-31 1.3 X-RAY STRUCTURE OF MONOCLINIC TURKEY EGG LYSOZYME AT 1.3 ANGSTROMS RESOLUTION
5HMJ 2016-03-02 1.3 Re-refinement of 4xan: hen lysozyme with carboplatin in sodium bromide solution
6F2J 2018-10-03 1.3 Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM sodium sulfate
4HTN 2013-05-15 1.3 Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 1.32 x 10e+12 X-ray photons
2HU3 2007-07-24 1.3 Parent Structure of Hen Egg White Lysozyme grown in acidic pH 4.8. Refinement for comparison with crosslinked molecules of lysozyme
1WTM 2004-12-14 1.33 X-ray structure of HEW Lysozyme Orthorhombic Crystal formed in the Earth's magnetic field
193L 1995-12-07 1.33 THE 1.33 A STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME
4NHI 2014-11-05 1.34 Crystal structure of Hen egg-white lysozyme in Tris buffer at pH 7.5 with Magnesium formate
6RT1 2019-05-29 1.34 Native tetragonal lysozyme - home source data
4XN6 2015-08-12 1.35 Crystal structure at room temperature of hen-egg lysozyme in complex with benzamidine
4LYC 2015-02-25 1.35 Cd ions within a lysoyzme single crystal
3RU5 2011-11-23 1.35 Silver Metallated Hen Egg White Lysozyme at 1.35 A
6QWY 2019-03-13 1.35 HEWL lysozyme, crystallized from NaCl solution
2CGI 2006-11-13 1.35 Siras structure of tetragonal lysozyme using derivative data collected at the high energy remote Holmium Kedge
6QWX 2019-03-13 1.35 HEWL lysozyme, crystallized from NiCl2 solution
4BAD 2012-11-14 1.35 Hen egg-white lysozyme structure in complex with the europium tris- hydroxymethyltriazoledipicolinate complex at 1.35 A resolution.
6MX9 2018-12-26 1.35 Lysozyme bound to 3-Aminophenol
2BPU 2006-08-24 1.35 The Kedge Holmium Derivative of Hen Egg-White Lysozyme at high resolution from Single Wavelength Anomalous Diffraction
4NGY 2014-05-28 1.35 Dialyzed HEW lysozyme batch crystallized in 0.75 M YbCl3 and collected at 100 K
6QWZ 2019-03-13 1.35 HEWL lysozyme, crystallized from KCl solution
6QX0 2019-03-13 1.35 HEWL lysozyme, crystallized from LiCl solution
6QWW 2019-03-13 1.35 HEWL lysozyme, crystallized from CuCl2 solution
3P66 2011-02-09 1.36 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme
5OOV 2018-08-29 1.37 Designed Ankyrin Repeat Protein (DARPin) ETVD-1 in complex with Lysozyme
2XBS 2010-11-24 1.37 Raman crystallography of Hen White Egg Lysozyme - High X-ray dose (16 MGy)
4NGW 2014-05-28 1.37 Dialyzed HEW lysozyme batch crystallized in 0.5 M YbCl3 and collected at 100 K
6QQE 2019-06-19 1.37 Room temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 20 kGy
3N9E 2011-06-08 1.38 Mite-y Lysozyme: Promite
4QEQ 2014-05-28 1.38 High resolution structure of egg white lysozyme
4XYY 2015-07-29 1.38 Hen Egg-White Lysozyme (HEWL) complexed with Zr(IV)-substituted Keggin-type polyoxometalate
5DL9 2015-09-16 1.38 Structure of Tetragonal Lysozyme in complex with Iodine solved by UWO Students
3A8Z 2010-03-09 1.4 Crystal structure of hen egg white lysozyme
4HTQ 2013-05-15 1.4 Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 6.70 x 10e+11 X-ray photons
5K2N 2017-05-31 1.4 lysozyme with nano particles
194L 1995-12-07 1.4 THE 1.40 A STRUCTURE OF SPACEHAB-01 HEN EGG WHITE LYSOZYME
2IHL 1994-01-31 1.4 LYSOZYME (E.C.3.2.1.17) (JAPANESE QUAIL)
2BLX 2005-09-07 1.4 HEWL before a high dose x-ray 'burn'
3N9A 2011-06-08 1.4 Mite-y Lysozyme: Vegemite
1RJC 2005-02-01 1.4 Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme
2BLY 2005-09-07 1.4 HEWL after a high dose x-ray 'burn'
4OWE 2014-09-24 1.41 PtCl6 binding to HEWL
6CIW 2019-01-02 1.42 Hen Egg White Lysozyme Cocrystallized with 1,3-Di(2-pyridyl)propane
6FRO 2018-10-03 1.42 Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM potassium iodide.
5I5Q 2016-05-18 1.42 Re refinement of 4mwn.
4NHP 2014-09-17 1.42 X-ray structure of the complex between the hen egg white lysozyme and pentachlorocarbonyliridate (III) (4 days)
6QQC 2019-06-19 1.42 Cryogenic temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 110 kGy
3ZEK 2012-12-26 1.43 Hen egg-white lysozyme structure determined at room temperature by in- situ diffraction in ChipX
5T3F 2016-11-30 1.45 hen egg-white lysozyme soaked with selenourea for 10 min
5WRA 2017-12-06 1.45 Crystal structure of hen egg-white lysozyme
5O6Q 2017-12-13 1.45 High pressure flash cooled hen egg white lysozyme
1HF4 2001-01-07 1.45 STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS
3A90 2010-03-09 1.45 Crystal structure of hen egg white lysozyme soaked with 1mM RhCl3
1SQ2 2004-08-24 1.45 Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme
4TWS 2014-08-20 1.45 Gadolinium Derivative of Tetragonal Hen Egg-White Lysozyme at 1.45 A Resolution
3WMK 2014-10-08 1.46 Crystal structure of Hen egg-white lysozyme in pH 4.5 Sodium Acetatewith 1M NaCl at 277K
2FBB 2006-03-28 1.46 Crystal Structure Analysis of Hexagonal Lysozyme
4YEM 2015-03-04 1.47 Carboplatin binding to HEWL in NaBr crystallisation conditions studied at an X-ray wavelength of 0.9163A - new refinement
6BO2 2018-05-16 1.48 Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL
4OWH 2014-09-24 1.48 PtBr6 binding to HEWL
6B7V 2018-07-25 1.48 Structure of hen egg-white lysozyme pre-treated with high-pressure homogenization at 120 MPa
6F1M 2018-05-09 1.48 Lysozyme crystallized in presence of 100 mM sodium phosphate at pH 4.5: low-humidity form
6B7W 2018-07-25 1.48 Structure of hen egg-white lysozyme pre-treated with high pressure (600 MPa) under isobaric condition
4NEB 2014-05-28 1.48 Previously de-ionized HEW lysozyme batch crystallized in 0.5 M MnCl2
3EXD 2008-10-28 1.49 Sulfur-SAD phased HEWL Crystal
3AGH 2011-03-23 1.49 X-ray analysis of lysozyme in the presence of 200 mM Arg
3QE8 2012-01-18 1.49 Crystal Structure Analysis of Lysozyme-bound fac-[Re(CO)3(H2O)(Im)]+
6G5Y 2018-06-27 1.49 The X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) terpyridine compound (acid pH)
4E3U 2012-07-25 1.5 Crystal Structure of Hen Egg White Lysozyme Cryoprotected in Proline
4A7D 2011-11-30 1.5 X-ray crystal structure of HEWL flash-cooled at high pressure
5V4I 2017-04-05 1.5 Osmium(II)(cymene)(chlorido)2-lysozyme adduct with one binding site
2C8O 2006-03-08 1.5 lysozyme (1sec) and UV lasr excited fluorescence
5L9J 2016-06-22 1.5 Room temperature X-ray diffraction of tetragonal HEWL. First data set (0.31 MGy)
5LAF 2016-12-21 1.5 Room temperature X-ray diffraction of tetragonal HEWL with 1M of uridine. First data set (0.31 MGy)
1XFP 2004-09-28 1.5 Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme
3B72 2008-09-09 1.5 Crystal structure of lysozyme folded in SDS and 2-methyl-2,4-pentanediol
5LIN 2016-08-03 1.5 Lysozyme, collected at rotation 1 degree per second
1VDQ 2004-04-13 1.5 The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
3A92 2010-03-09 1.5 Crystal structure of hen egg white lysozyme soaked with 10mM RhCl3
4NGK 2014-05-28 1.5 Previously de-ionized HEW lysozyme batch crystallized in 0.2 M CoCl2
3N9C 2011-06-08 1.5 Mite-y Lysozyme: Marmite
2C8P 2006-03-08 1.5 lysozyme (60sec) and UV laser excited fluorescence
3A95 2010-03-09 1.5 Crystal structure of hen egg white lysozyme soaked with 100mM RhCl3 at pH3.8
1AKI 1997-11-19 1.5 THE STRUCTURE OF THE ORTHORHOMBIC FORM OF HEN EGG-WHITE LYSOZYME AT 1.5 ANGSTROMS RESOLUTION
5D5F 2016-01-13 1.5 In meso in situ serial X-ray crystallography structure of lysozyme by bromine-SAD at 100 K
4AGA 2012-07-18 1.5 Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions
1VAU 2005-03-08 1.5 Xenon derivative of hen egg-white lysozyme
4W96 2014-12-31 1.5 Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2 followed by the reaction in deoxy-myoglobin solution
1A2Y 1998-04-29 1.5 HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
6F2K 2018-10-03 1.5 Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM potassium phosphate monobasic.
1ZVH 2006-04-04 1.5 Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme
5NJM 2017-09-27 1.5 Lysozyme room-temperature structure determined by serial millisecond crystallography
4CJ2 2014-05-21 1.5 Crystal structure of HEWL in complex with affitin H4
5LIO 2016-08-03 1.5 Lysozyme, collected at rotation 360 degree per second
1LZB 1995-05-08 1.5 DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY
3AZ6 2012-05-09 1.5 Crystal structure of Co/T-HEWL
2W1L 2008-10-28 1.51 THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 0.979 a wavelength 991 images data
4BAF 2012-11-14 1.51 Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution.
2X0A 2010-12-22 1.52 MPD-Lysozyme structure at 55.5 keV using a TRIXXEL CsI-aSi based digital imager and the new ESRF U22 undulator source at ID15
4NGL 2014-05-28 1.52 Previously de-ionized HEW lysozyme batch crystallized in 0.6 M CoCl2
5FHW 2017-01-11 1.52 Hen Egg-White Lysozyme (HEWL) complexed with Hf(IV)-substituted Wells Dawson-type polyoxometalate
3WW6 2015-06-17 1.53 Crystal Structure of hen egg white lysozyme mutant N46D/D52S
3WW5 2015-06-17 1.53 Crystal Structure of hen egg white lysozyme mutant N46E/D52S
1LZ8 1999-05-26 1.53 LYSOZYME PHASED ON ANOMALOUS SIGNAL OF SULFURS AND CHLORINES
6QQ3 2019-03-06 1.53 The room temperature structure of lysozyme via the acoustic levitation of a droplet
3TXD 2013-01-30 1.53 HEWL co-crystallization with carboplatin in aqueous media with glycerol as the cryoprotectant
4J7V 2014-02-19 1.54 Crystal structure of cross-linked hen egg white lysozyme soaked with 5mM [Ru(benzene)Cl2]2
2PC2 2008-04-01 1.54 Lysozyme Cocrystallized with Tris-dipicolinate Eu complex
4WLD 2015-04-08 1.54 High pressure protein crystallography of hen egg white lysozyme at 0.1 MPa
4WM3 2015-04-08 1.55 High pressure protein crystallography of hen egg white lysozyme at 710 MPa
3A91 2010-03-09 1.55 Crystal structure of hen egg white lysozyme soaked with 5mM RhCl3
5LVH 2016-09-21 1.55 Hen Egg White Lysozyme soaked with trans-Ru(DMSO)4Cl2
4W94 2014-12-31 1.55 Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2
4XEN 2015-04-08 1.55 High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa
3QNG 2012-01-18 1.55 Crystal Structure Analysis of Lysozyme-bound fac-[Re(CO)3(L-serine)]
5K2S 2017-05-31 1.55 Lysozyme with nano particles
1LZY 1995-02-27 1.55 X-RAY STRUCTURE OF TURKEY EGG LYSOZYME COMPLEX WITH DI-N-ACETYLCHITOBIOSE. RECOGNITION AND BINDING OF ALPHA-ANOMERIC FORM
4Z98 2015-10-14 1.55 Crystal Structure of Hen Egg White Lysozyme using Serial X-ray Diffraction Data Collection
4N9R 2015-12-30 1.55 X-ray structure of the complex between hen egg white lysozyme and pentacholrocarbonyliridate(III) (1 day)
6RT9 2019-06-05 1.55 Orthorhombic lysozyme grown with 300g/L sucrose
3A94 2010-03-09 1.55 Crystal structure of hen egg white lysozyme soaked with 100mM RhCl3
5FCP 2016-04-13 1.55 X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN AT LONG INCUBATION TIMES
3A93 2010-03-09 1.55 Crystal structure of hen egg white lysozyme soaked with 30mM RhCl3
4DD2 2012-04-25 1.55 EVAL processed HEWL, carboplatin aqueous glycerol
3E3D 2008-10-28 1.55 Structure of hen egg white lysozyme with the magic triangle I3C
2HTX 2007-05-22 1.56 Crystal Structure Analysis of Hen Egg White Lysozyme Crosslinked by Polymerized Glutaraldehyde in Acidic Environment
6JXP 2019-05-15 1.56 Room temperature structure of lysozyme delivered in LCP by serial millisecond crystallography
3WVY 2015-06-10 1.56 Structure of D48A hen egg white lysozyme in complex with (GlcNAc)4
5NE0 2017-06-14 1.57 Room temperature in-situ structure of hen egg-white lysozyme from crystals enclosed between ultrathin silicon nitride membranes
4NWE 2014-09-24 1.58 Lysozyme UNDER 30 BAR PRESSURE OF NITROUS OXIDE
4NGO 2014-05-28 1.58 Previously de-ionized HEW lysozyme batch crystallized in 1.0 M CoCl2
6B7U 2018-07-25 1.58 Structure of hen egg-white lysozyme without high-pressure pre-treatment
3WVX 2015-06-10 1.58 Structure of D48A hen egg white lysozyme
5A3Z 2015-11-11 1.59 Structure of monoclinic Lysozyme obtained by multi crystal data collection
3KAM 2010-02-16 1.59 Hen Egg White Lysozyme Derivatized with rhenium(I) diaquatricarbonyl cation
3TXB 2013-01-30 1.59 HEWL co-crystallization with cisplatin in aqueous media with glycerol as the cryoprotectant
2B5Z 2006-10-03 1.6 Hen lysozyme chemically glycosylated
3AGG 2011-03-23 1.6 X-ray analysis of lysozyme in the absence of Arg
3P4Z 2011-02-09 1.6 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme
5K2R 2017-05-31 1.6 Crystal structure of lysozyme
3P68 2011-02-09 1.6 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme
2F2N 2006-04-25 1.6 Triclinic hen egg lysozyme cross-linked by glutaraldehyde
1YIL 2005-02-08 1.6 Structure of Hen egg white lysozyme soaked with Cu2-Xylylbicyclam
5LVJ 2016-09-28 1.6 Hen Egg White Lysozyme soaked with [H2Ind][trans-RuCl4(DMSO)(HInd)]
1T3P 2005-07-26 1.6 Half-sandwich arene ruthenium(II)-enzyme complex
1LZA 1995-05-08 1.6 DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY
1LKR 1998-04-29 1.6 MONOCLINIC HEN EGG WHITE LYSOZYME IODIDE
4WM1 2015-04-08 1.6 High pressure protein crystallography of hen egg white lysozyme at 500 MPa
4DD7 2012-04-25 1.6 EVAL processed HEWL, carboplatin DMSO glycerol
1B2K 1998-12-02 1.6 Structural effects of monovalent anions on polymorphic lysozyme crystals
4WM4 2015-04-08 1.6 High pressure protein crystallography of hen egg white lysozyme at 800 MPa
5I4W 2017-02-15 1.6 Exploring the onset of lysozyme denaturation by urea
4DD9 2012-04-25 1.6 EVAL processed HEWL, carboplatin DMSO paratone
4WM2 2015-04-08 1.6 High pressure protein crystallography of hen egg white lysozyme at 600 MPa
1VAT 2005-03-08 1.6 Iodine derivative of hen egg-white lysozyme
4WLX 2015-04-08 1.6 High pressure protein crystallography of hen egg white lysozyme at 280 MPa
5LAG 2016-12-21 1.6 Room temperature X-ray diffraction of tetragonal HEWL with 1M of uridine. Second data set (0.62 MGy)
2ZQ3 2008-09-30 1.6 The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.6 angstroms resolution
4WLT 2015-04-08 1.6 High pressure protein crystallography of hen egg white lysozyme at 190 MPa
4P2E 2014-04-09 1.6 Acoustic transfer of protein crystals from agar pedestals to micromeshes for high throughput screening of heavy atom derivatives
1GPQ 2003-03-11 1.6 Structure of ivy complexed with its target, HEWL
3TXI 2013-01-30 1.6 HEWL co-crystallization with carboplatin in DMSO media with paratone as the cryoprotectant
3IJU 2010-08-11 1.6 Chicken egg white lysozyme by highly ordered APA (Anodic Porous Alumina) nanotemplate crystallization method
1VDS 2004-04-13 1.6 The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space
4WM5 2015-04-08 1.6 High pressure protein crystallography of hen egg white lysozyme at 890 MPa
5I54 2017-02-15 1.61 Exploring onset of lysozyme denaturation by urea - soak period 4 hours
5I4X 2017-02-15 1.61 Exploring onset of lysozyme denaturation by urea - soak period 2 hours
5I53 2017-02-15 1.61 Exploring onset of lysozyme denaturation by urea - soak period 7 hours
5I4Y 2017-02-15 1.61 Exploring onset of lysozyme denaturation by urea: soak period 10 hours.
3AZ4 2012-05-09 1.62 Crystal structure of Co/O-HEWL
4OWC 2014-09-24 1.62 PtI6 binding to HEWL
4WLY 2015-04-08 1.62 High pressure protein crystallography of hen egg white lysozyme at 380 MPa
2YVB 2007-04-24 1.62 High resolution X-ray crystal structure of Tetragonal Hen egg white lysozyme
1LCN 1998-11-04 1.63 Monoclinic hen egg white lysozyme, thiocyanate complex
4NFV 2014-05-28 1.63 Previously de-ionized HEW lysozyme batch crystallized in 1.1 M MnCl2
1IR8 2001-10-03 1.63 IM mutant of lysozyme
2HU1 2007-05-22 1.63 Crystal structure Analysis of Hen Egg White Lyszoyme
1ZVY 2006-04-04 1.63 Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme
1DPW 2000-01-03 1.64 STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH MPD
1H6M 2001-08-30 1.64 Covalent glycosyl-enzyme intermediate of hen egg white lysozyme
4NGV 2014-05-28 1.64 Previously de-ionized HEW lysozyme batch crystallized in 0.5 M YbCl3
3QY4 2011-03-30 1.65 Crystallization and in situ data collection of Lysozyme using the Crystal Former
4NWH 2014-09-24 1.65 Lysozyme UNDER 30 BAR PRESSURE OF XENON
5K2K 2017-05-31 1.65 Crystal structure of lysozyme
1W6Z 2004-11-10 1.65 High Energy Tetragonal Lysozyme X-ray Structure
1TEW 1995-01-26 1.65 STRUCTURE OF HEXAGONAL TURKEY EGG WHITE LYSOZYME AT 1.65 ANGSTROMS RESOLUTION
2F30 2006-04-25 1.65 Triclinic cross-linked Lysozyme soaked with 4.5M urea
3EMS 2008-10-21 1.65 Effect of Ariginine on lysozyme
2F4G 2006-04-25 1.65 Triclinic cross-linked lysozyme soaked in bromoethanol 1M
6IRJ 2019-05-22 1.65 Crystal structure of lysozyme by fixed-target serial femtosecond crystallography
3ULR 2012-01-11 1.65 Lysozyme contamination facilitates crystallization of a hetero-trimericCortactin:Arg:Lysozyme complex
4NHT 2014-09-17 1.65 X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (6 days)
5LAN 2017-08-30 1.65 Room temperature X-ray diffraction of tetragonal HEWL with 1M of uridine. Third data set (0.93 MGy)
3A34 2010-06-16 1.65 Effect of Ariginine on lysozyme
1DPX 2000-01-03 1.65 STRUCTURE OF HEN EGG-WHITE LYSOZYME
4J1B 2013-04-03 1.66 X-ray structure of the adduct between hen egg white lysozyme and AziRu (black crystal)
2A7D 2005-07-19 1.66 On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength
5YIN 2018-07-25 1.66 Hen egg-white lysozyme precipitant-free orthorhombic form
4UWN 2014-12-10 1.67 Lysozyme soaked with a ruthenium based CORM with a methione oxide ligand (complex 6b)
4B1A 2013-02-06 1.67 Crystal structure of lysozyme with Keggin molecule
2XJW 2011-01-26 1.67 Lysozyme-CO releasing molecule adduct
6RO5 2019-06-19 1.68 1Yr-Y: Lysozyme with Re Cluster 1 year on shelf
3TXF 2013-01-30 1.69 HEWL co-crystallization with cisplatin in DMSO media with glycerol as the cryoprotectant
3TXH 2013-01-30 1.69 HEWL co-crystallization with carboplatin in DMSO media with glycerol as the cryoprotectant
4OWB 2014-09-24 1.69 Cisplatin binding to HEWL under sodium bromide crystallisation conditions
6FRQ 2018-10-03 1.69 Structure of tetragonal Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM Potassium sodium tartrate tetrahydrate.
1LSF 1994-09-30 1.7 THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
5APC 2016-01-13 1.7 Hen Egg White Lysozyme illuminated with 0.4THz radiation
1F10 2000-06-21 1.7 CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 AT 88% RELATIVE HUMIDITY
5D5C 2016-01-13 1.7 In meso in situ serial X-ray crystallography structure of lysozyme at 100 K
4NSJ 2014-10-15 1.7 Carboplatin binding to HEWL in 2M NH4formate, 0.1M HEPES at pH 7.5
4NGI 2014-05-28 1.7 Previously de-ionized HEW lysozyme crystallized in 1.0 M RbCl and collected at 125K
1LSM 1994-11-30 1.7 THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES
6IG6 2018-11-07 1.7 Crystal structure of lysozyme delivered in polyacrylamide using x-ray free electron laser
5L3I 2016-06-15 1.7 Re-refinement of 4dd6; cisplatin coordination chemistry determination at hen egg white lysozyme His15
1LZN 1999-04-01 1.7 NEUTRON STRUCTURE OF HEN EGG-WHITE LYSOZYME
2W1X 2008-11-04 1.7 The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data
3TXE 2013-01-30 1.7 HEWL co-crystallization with carboplatin in aqueous media with paratone as the cryoprotectant
5L3H 2016-06-15 1.7 Re-refinement of 4dd4; cisplatin coordination chemistry determination at hen egg white lysozyme His15 with standard uncertainties
1VDP 2004-04-13 1.7 The crystal structure of the monoclinic form of hen egg white lysozyme at 1.7 angstroms resolution in space
2AUB 2005-12-06 1.7 Lysozyme structure derived from thin-film-based crystals
1LSD 1994-09-30 1.7 THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
5APF 2016-01-13 1.7 Hen Egg White Lysozyme reference dataset even frames
5KKI 2017-02-15 1.7 1.7-Angstrom in situ Mylar structure of hen egg-white lysozyme (HEWL) at 100 K
5NJQ 2017-10-18 1.7 Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 1s time-delay, phased with 4ET8
1HEL 1993-10-31 1.7 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
5NJR 2017-10-18 1.7 Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 50s time-delay, phased with 4ET8
5NJP 2017-10-18 1.7 Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 1s time-delay, phased with 1HEW
3IJV 2010-08-11 1.7 Chicken egg white lysozyme by classical hanging drop vapour diffusion method
5APD 2016-01-13 1.7 Hen Egg White Lysozyme not illuminated with 0.4THz radiation
1YQV 2005-04-26 1.7 The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution
4BS7 2013-10-30 1.7 Hen egg-white lysozyme structure determined at room temperature by in- situ diffraction and SAD phasing in ChipX
4N1C 2014-10-29 1.7 Structural evidence for antigen receptor evolution
4DD3 2012-04-25 1.7 EVAL processed HEWL, carboplatin aqueous paratone
4DD0 2012-04-25 1.7 EVAL processed HEWL, cisplatin aqueous glycerol
4NGZ 2014-05-28 1.7 Previously de-ionized HEW lysozyme crystallized in 0.5 M YbCl3/30% (v/v) glycerol and collected at 125K
1LSE 1994-09-30 1.7 THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
4WG1 2015-05-06 1.7 Room temperature crystal structure of lysozyme determined by serial synchrotron crystallography (micro focused beam - crystFEL)
1LSC 1994-09-30 1.7 THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
4R6C 2015-02-04 1.7 X-ray diffraction in temporally and spatially resolved biomolecular science: the X-ray crystal structure of hen egg white lysozyme cocrystallized with Ta6Br12 and then a crystal soaked in K2PtBr6
5HLL 2016-03-02 1.7 Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO.
4DD1 2012-04-25 1.7 EVAL processed HEWL, cisplatin aqueous paratone
1BGI 1998-10-28 1.7 ORTHORHOMBIC LYSOZYME CRYSTALLIZED AT HIGH TEMPERATURE (310K)
5APE 2016-01-13 1.7 Hen Egg White Lysozyme reference dataset odd frames
1LSB 1994-09-30 1.7 THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
5LVI 2016-09-28 1.7 Hen Egg White Lysozyme soaked with [HIsq][trans-RuCl4(DMSO)(Isq)]
1UAC 2004-03-23 1.7 Crystal Structure of HYHEL-10 FV MUTANT SFSF Complexed with TURKEY WHITE LYSOZYME
5NJS 2017-10-18 1.7 Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 50s time-delay, phased with 1HEW
3TXG 2013-01-30 1.7 HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant
2Q0M 2007-12-11 1.7 Tricarbonylmanganese(I)-lysozyme complex : a structurally characterized organometallic protein
4WG7 2015-05-06 1.7 Room-temperature crystal structure of lysozyme determined by serial synchrotron crystallography using a nano focused beam.
1T6V 2004-08-24 1.7 Crystal structure analysis of the nurse shark new antigen receptor (NAR) variable domain in complex with lysozyme
1VDT 2004-04-13 1.7 The crystal structure of the tetragonal form of hen egg white lysozyme at 1.7 angstroms resolution under basic conditions in space
1LZ9 1999-05-26 1.7 ANOMALOUS SIGNAL OF SOLVENT BROMINES USED FOR PHASING OF LYSOZYME
5LA5 2016-12-21 1.7 Room temperature X-ray diffraction of tetragonal HEWL. Second data set (0.62 MGy)
1LSA 1994-09-30 1.7 THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
4D9Z 2013-01-16 1.71 Lysozyme at 318K
1KXX 1997-11-26 1.71 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
4PRQ 2014-09-10 1.72 CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH SCLX4 AT 1.72 A RESOLUTION
1LYS 1994-04-30 1.72 X-RAY STRUCTURE OF A MONOCLINIC FORM OF HEN EGG-WHITE LYSOZYME CRYSTALLIZED AT 313K. COMPARISON OF TWO INDEPENDENT MOLECULES
1H87 2002-01-15 1.72 Gadolinium derivative of tetragonal Hen Egg-White Lysozyme at 1.7 A resolution
4LFP 2013-10-02 1.72 X-ray structure of the adduct between hen egg white lysozyme and a homoleptic gold(I) complex with the saccharynate ligand
5OOY 2018-08-29 1.72 Designed Ankyrin Repeat Protein (DARPin) VHAH-1 in complex with Lysozyme
2W1Y 2008-11-25 1.73 THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 1.540 A wavelength 180 images data
4PPO 2015-01-14 1.73 First Crystal Structure for an Oxaliplatin-Protein Complex
6A4N 2019-03-13 1.75 HEWL crystals soaked in 2.5M GuHCl for 8 minutes
6A4Q 2019-03-13 1.75 HEWL crystals soaked in 2.5M GuHCl for 110 minutes
2H9J 2007-04-10 1.75 Structure of Hen egg white lysozyme soaked with Ni2-Xylylbicyclam
1LMA 1994-01-31 1.75 PROTEIN HYDRATION AND WATER STRUCTURE: X-RAY ANALYSIS OF A CLOSELY PACKED PROTEIN CRYSTAL WITH VERY LOW SOLVENT CONTENT
5MJJ 2017-12-20 1.75 Single-shot pink beam serial crystallography: Lysozyme
5IHG 2016-12-07 1.75 The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme a compound I, a platin(II) compound containing a O, S bidentate ligand
1HEW 1994-01-31 1.75 REFINEMENT OF AN ENZYME COMPLEX WITH INHIBITOR BOUND AT PARTIAL OCCUPANCY. HEN EGG-WHITE LYSOZYME AND TRI-N-ACETYLCHITOTRIOSE AT 1.75 ANGSTROMS RESOLUTION
3A96 2010-03-09 1.75 Crystal structure of hen egg white lysozyme soaked with 100mM RhCl3 at pH2.2
6A4O 2019-03-13 1.75 HEWL crystals soaked in 2.5M GuHCl for 20 minutes
1IOT 2001-04-11 1.75 STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION
5ILC 2016-12-07 1.75 The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme a compound 2, a platin(II) compound containing a O, S bidentate ligand
1G7J 2000-11-22 1.75 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H)
1RFP 1997-05-15 1.75 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
1UIH 1997-11-26 1.75 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
3RT5 2011-06-15 1.75 Lysozyme in 30% propanol
2H9K 2007-04-10 1.75 Structure of Hen egg white lysozyme soaked with Ni-cyclam
1YIK 2005-02-08 1.75 Structure of Hen egg white lysozyme soaked with Cu-cyclam
1UIA 1997-11-26 1.76 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
1IOR 2001-04-11 1.76 STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION
6FTR 2018-10-10 1.76 Serial Femtosecond Crystallography at Megahertz pulse rates
1IOS 2001-04-11 1.76 STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION
6JXQ 2019-05-15 1.76 Room temperature structure of lysozyme delivered in polyacrylamide by serial millisecond crystallography
6A4P 2019-03-13 1.76 HEWL crystals soaked in 2.5M GuHCl for 40 minutes
5HNC 2016-07-20 1.76 Synchrotron X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels
1UIB 1997-11-26 1.76 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
1JEF 1997-10-15 1.77 TURKEY LYSOZYME COMPLEX WITH (GLCNAC)3
4UWV 2014-12-10 1.77 Lysozyme soaked with a ruthenium based CORM with a pyridine ligand (complex 8)
1GWD 2002-06-06 1.77 Tri-iodide derivative of hen egg-white lysozyme
3W6A 2014-02-19 1.77 Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked wiht 5mM [Ru(benzene)Cl2]2
2W1M 2008-11-04 1.78 THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 2.070 A WAVELENGTH with 2theta 30 degrees data
1FLU 2000-09-06 1.78 HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE
1FN5 2000-09-06 1.78 HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE
4UWU 2014-12-10 1.78 Lysozyme soaked with a ruthenium based CORM with a pyridine ligand (complex 7)
5II3 2016-12-07 1.78 The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 3, a platin(II) compound containing a O, S bidentate ligand
1N4F 2003-05-06 1.78 Para-Arsanilate Derivative of Hen Egg-White Lysozyme
5OLE 2018-08-29 1.78 X-ray structure of the adduct formed upon reaction of hen egg white lysozyme with a tetranuclear Pt-thiosemicarbazone compound
5TK0 2017-04-05 1.79 Lysozyme structure collected with 3D printed polymer mounts
4J1A 2013-04-03 1.79 X-ray structure of the adduct between hen egg white lysozyme and AziRu (green crystal)
5E4P 2016-08-31 1.79 X-ray Crystal Structure Analysis of Magnetically Oriented Microcrystals of Lysozyme at 1.8 angstrom Resolution
1KXY 1997-11-26 1.79 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
1IOQ 2001-04-11 1.79 STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION
4OOT 2014-12-17 1.8 X-ray structure of the protein-gold adduct formed upon reaction of Aubipic with hen egg white lysozyme
1J1O 2003-01-14 1.8 Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme
1LJF 2002-10-19 1.8 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% SUCROSE
1UUZ 2004-01-14 1.8 IVY:A NEW FAMILY OF PROTEIN
5FEL 2016-05-25 1.8 Hen egg lysozyme at room temperature solved from dataset acquired by oscillation method
4GCB 2013-01-02 1.8 100K X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL
1YKZ 2005-07-05 1.8 Effect of alcohols on protein hydration
2DQD 2007-01-23 1.8 Crystal structure of hyhel-10 FV mutant (Hy50f) complexed with hen egg lysozyme
4XJB 2015-06-03 1.8 X-ray structure of Lysozyme1
1HEO 1993-10-31 1.8 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
4DDC 2012-04-25 1.8 EVAL processed HEWL, cisplatin DMSO NAG silicone oil
1AT6 1998-02-25 1.8 HEN EGG WHITE LYSOZYME WITH A ISOASPARTATE RESIDUE
1BVX 1998-09-23 1.8 THE 1.8 A STRUCTURE OF GEL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
1J1P 2003-01-14 1.8 Crystal structure of HyHEL-10 Fv mutant LS91A complexed with hen egg white lysozyme
1FLQ 2000-09-06 1.8 HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE
4DT3 2012-09-12 1.8 Crystal structure of zinc-charged lysozyme
3A6B 2009-12-22 1.8 Crystal Structure of HyHEL-10 Fv mutant LN32D complexed with hen egg white lysozyme
5B07 2016-01-13 1.8 Lysozyme (denatured by DCl and refolded)
2DQC 2007-01-23 1.8 Crystal structure of hyhel-10 FV mutant(Hy33f) complexed with hen egg lysozyme
3RZ4 2011-05-25 1.8 Hen egg-white lysozyme in HEPES buffer at pH 7.5
2DQJ 2007-01-23 1.8 Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution
3A6C 2009-12-22 1.8 Crystal Structure of HyHEL-10 Fv mutant LN92D complexed with hen egg white lysozyme
1LZG 1995-05-08 1.8 DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY
1HEP 1993-10-31 1.8 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
5B06 2016-01-13 1.8 Lysozyme (denatured by NaOD and refolded)
5FDJ 2016-05-25 1.8 Hen egg lysozyme at room temperature solved from datasets acquired by ultrasonic acoustic levitation method and processed by CrystFEL
4XJD 2015-06-03 1.8 X-ray structure of Lysozyme2
1VFB 1994-05-31 1.8 BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
1G7I 2000-11-22 1.8 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F)
1BWI 1998-09-30 1.8 THE 1.8 A STRUCTURE OF MICROBATCH OIL DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
2WAR 2010-02-09 1.8 Hen Egg White Lysozyme E35Q chitopentaose complex
1LZD 1995-05-08 1.8 DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY
6RTA 2019-06-26 1.8 Tetragonal lysozyme grown with 300g/L Ficoll
5AMY 2016-10-05 1.8 Crystal Structure of Hen egg white lysozyme processed with the CrystalDirect automated mounting and cryo-cooling technology
3A67 2009-12-22 1.8 Crystal Structure of HyHEL-10 Fv mutant LN31D complexed with hen egg white lysozyme
1AZF 1998-02-25 1.8 CHICKEN EGG WHITE LYSOZYME CRYSTAL GROWN IN BROMIDE SOLUTION
3SP3 2011-07-27 1.8 Lysozyme in 20% sucrose
6G5C 2018-10-24 1.8 Interaction of TiO2 nanoparticles (NM-101) with Lysozyme
2XTH 2010-12-08 1.8 K2PtBr6 binding to lysozyme
1BWH 1998-09-30 1.8 THE 1.8 A STRUCTURE OF GROUND CONTROL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
1HEQ 1993-10-31 1.8 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
1LJH 2002-10-19 1.8 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 5% GLYCEROL
5WR9 2017-12-06 1.8 Crystal structure of hen egg-white lysozyme
1BWJ 1998-09-30 1.8 THE 1.8 A STRUCTURE OF MICROGRAVITY GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
1HEM 1993-10-31 1.8 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
5B05 2016-01-13 1.8 Lysozyme (control experiment)
4WOA 2015-02-18 1.8 Lysozyme Multiple Crystals After Surface Acoustic Wave Alignment
5LYM 1995-10-15 1.8 STUDIES OF MONOCLINIC HEN EGG WHITE LYSOZYME. IV. X-RAY REFINEMENT AT 1.8 ANGSTROM RESOLUTION AND A COMPARISON OF THE VARIABLE REGIONS IN THE POLYMORPHIC FORMS
2I25 2007-03-06 1.8 Crystal structure analysis of the nurse shark New antigen Receptor PBLA8 variable domain in complex with lysozyme
1LZE 1995-05-08 1.8 DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY
4XJG 2015-06-03 1.8 X-ray structure of Lysozyme B2
1HER 1993-10-31 1.8 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
1LZC 1995-05-08 1.8 DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY
1AT5 1998-02-25 1.8 HEN EGG WHITE LYSOZYME WITH A SUCCINIMIDE RESIDUE
4OWA 2014-09-24 1.8 Carboplatin binding to HEWL under sodium iodide crystallisation conditions
132L 1993-10-31 1.8 STRUCTURAL CONSEQUENCES OF REDUCTIVE METHYLATION OF LYSINE RESIDUES IN HEN EGG WHITE LYSOZYME: AN X-RAY ANALYSIS AT 1.8 ANGSTROMS RESOLUTION
1J1X 2003-01-14 1.8 Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme
5K7O 2017-04-05 1.8 MicroED structure of lysozyme at 1.8 A resolution
1HEN 1993-10-31 1.8 STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME
5FEK 2016-05-25 1.8 Hen egg lysozyme at room temperature solved from 3600 diffraction images acquired by ultrasonic acoustic levitation method and processed by CrystFEL
1NBY 2003-04-01 1.8 Crystal Structure of HyHEL-63 complexed with HEL mutant K96A
4XJF 2015-06-03 1.8 X-ray structure of Lysozyme B1
4PHI 2015-01-14 1.81 Crystal structure of HEWL with hexatungstotellurate(VI)
3OJP 2011-03-02 1.81 D52N Mutant of Hen Egg White Lysozyme (HEWL)
1FLW 2000-09-06 1.81 HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE
4HSF 2013-10-30 1.82 Lysozyme with Arginine at 318K
3OK0 2011-03-02 1.82 E35A Mutant of Hen Egg White Lysozyme (HEWL)
1HC0 2005-11-14 1.82 structure of lysozyme with periodate
4NG1 2014-05-28 1.82 Previously de-ionized HEW lysozyme batch crystallized in 1.9 M CsCl
4EOF 2013-04-17 1.83 Lysozyme in the presence of arginine
1FLY 2000-09-06 1.83 HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE
2G4Q 2007-02-20 1.84 Anomalous substructure of lysozyme at pH 8.0
2G4P 2007-02-20 1.84 Anomalous substructure of lysozyme at pH 4.5
6MUZ 2019-03-27 1.84 Lysozyme, room temperature structure solved by serial 3 degree oscillation crystallography
1B0D 1998-11-11 1.84 Structural effects of monovalent anions on polymorphic lysozyme crystals
4WL6 2015-05-06 1.85 Raster-scanning protein crystallography using micro and nano-focused synchrotron beams
5OB8 2017-07-26 1.85 X-ray structure of the adduct formed upon reaction of lysozyme with the compound fac-[RuII(CO)3Cl2(N3-MIM), MIM=methyl-imidazole (crystals grown using NaCl)
2A7F 2005-07-19 1.85 On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength
1UIF 1997-11-26 1.85 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
5ILF 2016-12-07 1.85 The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 4, a platin(II) compound containing a O, S bidentate ligand
4WM6 2015-04-08 1.85 High pressure protein crystallography of hen egg white lysozyme at 950 MPa
1RI8 2005-02-01 1.85 Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme
4NY5 2014-03-26 1.85 X-ray structure of the adduct formed between hen egg white lysozyme and NAMI-A
1G7H 2000-11-22 1.85 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A)
5NJ1 2018-05-16 1.85 The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and arsenoplatin-1
4Z46 2015-05-27 1.85 X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin
1NBZ 2003-04-01 1.85 Crystal Structure of HyHEL-63 complexed with HEL mutant K97A
5F9U 2016-04-13 1.85 X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 20 DEGREES
1KIQ 1996-12-23 1.85 FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
1UC0 2003-04-22 1.85 Crystal structure of wild-type hen-egg white lysozyme singly labeled with 2',3'-epoxypropyl beta-glycoside of N-acetyllactosamine
4GN4 2013-08-21 1.86 OBody AM2EP06 bound to hen egg-white lysozyme
3RW8 2011-05-25 1.86 Crystal structure of lysozyme in 40% ethanol
3RNX 2011-05-18 1.86 Crystal Structure of Lysozyme in 30% ethanol
4GN5 2013-08-21 1.86 OBody AM3L15 bound to hen egg-white lysozyme
4NIJ 2014-09-17 1.86 X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (30 days)
4FJR 2013-07-03 1.86 Mode of interaction of Merocyanine 540 with HEW Lysozyme
6BRE 2018-01-24 1.86 Hen Egg-White Lysozyme cocrystallized with Cadmium sulphate using CuKalpha source.
5OB6 2017-07-26 1.88 X-ray structure of the adduct formed upon reaction of lysozyme with the compound fac-[RuII(CO)3Cl2(N3-IM), IM=imidazole
4II8 2013-12-25 1.88 Lysozyme with Benzyl alcohol
5YKY 2018-09-26 1.88 Crystal Structure of Cross-Linked Tetragonal Hen Egg White Lysozyme Soaked with 10 mM Rose Bengal and 10mM H2PtCl6
4ZIX 2015-08-12 1.89 Structure of HEWL using Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase
4Z41 2015-09-02 1.89 X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Compound with a S,O Bidentate Ligand (9a=Chloro-(1-(3'-hydroxy)-3-(methylthio)-3-thioxo-prop-1-en-1-olate-O,S)-(dimethylsulfoxide-S)-platinum(II))
1JJ1 2001-11-02 1.9 CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 4.6 IN PRESENCE OF 5% SORBITOL
1JJ3 2001-11-02 1.9 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6
1RCM 1993-10-31 1.9 CRYSTAL STRUCTURE OF A UBIQUITIN-DEPENDENT DEGRADATION SUBSTRATE: A THREE-DISULFIDE FORM OF LYSOZYME
1JIY 2001-11-02 1.9 CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN IN PRESENCE 20% SORBITOL
3A3R 2009-11-03 1.9 Structure of N59D HEN EGG-WHITE LYSOZYME
1YKY 2005-07-05 1.9 Effect of alcohols on protein hydration
4RW1 2015-05-20 1.9 Hen egg-white lysozyme structure from a spent-beam experiment at LCLS: original beam
1G7M 2000-11-22 1.9 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
4ET8 2012-06-13 1.9 Hen egg-white lysozyme solved from 40 fs free-electron laser pulse data
1IR7 2001-10-03 1.9 IM mutant of lysozyme
1VED 2004-04-13 1.9 The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.9 angstroms resolution in space
3LYT 1993-10-31 1.9 COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES
2DQE 2007-01-23 1.9 Crystal structure of hyhel-10 FV mutant (Hy53a) complexed with hen egg lysozyme
6LYT 1993-10-31 1.9 COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES
6H3B 2018-09-12 1.9 Lysozyme: Machining protein microcrystals for structure determination by electron diffraction
6H0L 2018-09-05 1.9 Hen egg-white lysozyme structure determined with data from the EuXFEL, 9.22 keV photon energy
1IR9 2001-10-03 1.9 IM mutant of lysozyme
1NDG 2003-06-03 1.9 Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme
1YL0 2005-07-05 1.9 Effect of alcohols on protein hydration
1JIS 2001-11-02 1.9 CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN AT PH 4.6
2I6Z 2007-01-02 1.9 X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme
5M1Y 2016-10-26 1.9 The case of 1lkr held at the PDB and its variable amino acid occupancies; re refinement of 4ow9 to correct this
3TMX 2012-08-22 1.9 X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Dose=1.9MGy)
1JTP 2001-12-05 1.9 Degenerate interfaces in antigen-antibody complexes
1HSX 1998-08-12 1.9 LYSOZYME GROWN AT BASIC PH AND ITS LOW HUMIDITY VARIANT
3TMU 2012-08-22 1.9 X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Undosed)
1F0W 2000-06-21 1.9 CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5
1LSY 1995-01-26 1.9 CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT
1DKK 1996-07-11 1.9 BOBWHITE QUAIL LYSOZYME WITH NITRATE
3TMW 2012-08-22 1.9 X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Undosed)
1Z55 2005-07-05 1.9 Effect of alcohols on protein hydration
4LYT 1993-10-31 1.9 COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES
4ET9 2012-06-13 1.9 Hen egg-white lysozyme solved from 5 fs free-electron laser pulse data
5C6I 2015-07-08 1.9 Crystal Structure of Gadolinium derivative of HEWL solved using Free-Electron Laser radiation
1LSN 1994-11-30 1.9 THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES
1JIT 2001-11-02 1.9 CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN IN PRESENCE 30% TREHALOSE
1LJG 2002-10-19 1.9 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 5% GLYCEROL
1UA6 2004-03-09 1.9 Crystal structure of HYHEL-10 FV MUTANT SFSF complexed with HEN EGG WHITE LYSOZYME complex
1YL1 2005-07-05 1.9 Effect of alcohols on protein hydration
4ETD 2012-06-13 1.9 Lysozyme, room-temperature, rotating anode, 0.0026 MGy
4ETE 2012-06-13 1.9 Lysozyme, room-temperature, rotating anode, 0.0021 MGy
4N0J 2014-11-12 1.9 Crystal structure of dimethyllysine hen egg-white lysozyme in complex with sclx4 at 1.9 A resolution
1JJ0 2001-11-02 1.9 CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN IN PRESENCE of 30% SUCROSE
2EIZ 2008-03-18 1.9 Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex
5OER 2017-10-25 1.9 Hen egg-white lysozyme refined against 5000 9 keV diffraction patterns
3TMV 2012-08-22 1.9 X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Dose=0.12MGy)
1HHL 1993-10-31 1.9 THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES
1YKX 2005-07-05 1.9 Effect of alcohols on protein hydration
4RLM 2015-02-25 1.9 Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with CrystFEL
5LYT 1993-10-31 1.9 COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES
4ETB 2012-06-13 1.91 lysozyme, room temperature, 200 kGy dose
4ETC 2012-06-13 1.91 Lysozyme, room temperature, 24 kGy dose
4ETA 2012-06-13 1.91 Lysozyme, room temperature, 400 kGy dose
4NHQ 2014-09-17 1.92 X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (5 days)
6QQD 2019-06-19 1.92 Cryogenic temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 10 MGy
4TUN 2014-07-09 1.92 Crystal structure of Chicken egg white lysozyme adduct with Organophosphorus pesticide Monochrotophos
4TSC 2015-07-08 1.92 Structure of a lysozyme antibody complex
2LYO 1998-05-27 1.93 CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 90% ACETONITRILE-WATER
3LYO 1998-05-27 1.93 CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 95% ACETONITRILE-WATER
1LYO 1998-05-27 1.93 CROSS-LINKED LYSOZYME CRYSTAL IN NEAT WATER
5F9X 2016-04-13 1.94 X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 55 DEGREES
4R0F 2015-07-22 1.94 Structure of Lysozyme Dimer at 318K
1UID 1997-11-26 1.95 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
1UIG 1997-11-26 1.95 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
4ZEE 2015-05-27 1.95 X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin (preparation 2)
4GN3 2013-08-21 1.95 OBody AM1L10 bound to hen egg-white lysozyme
4WL7 2015-05-06 1.95 Room-temperature crystal structure of lysozyme determined by serial synchrotron crystallography using a micro focused beam (Conventional resolution cut-off)
2F4A 2006-04-25 1.95 Triclinic cross-linked lysozyme soaked with thiourea 1.5M
3M18 2010-06-30 1.95 Crystal structure of variable lymphocyte receptor VLRA.R2.1 in complex with hen egg lysozyme
6QQF 2019-06-19 1.95 Room temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 100 kGy
4TSB 2015-07-08 1.95 Structure of a lysozyme antibody complex
1UIC 1997-11-26 1.95 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
1LJ4 2002-10-19 1.95 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6
1UIE 1997-11-26 1.95 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
6G5V 2018-07-04 1.96 The X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) terpyridine compound (pH 7.0)
1KXW 1997-11-26 1.96 ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS
6GOB 2018-07-25 1.96 X-ray structure of the adduct formed upon reaction of lysozyme with a Pd(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated sulphonate side chain
6QEA 2019-03-27 1.96 The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
4ZFP 2015-06-24 1.96 A new crystal structure for the adduct formed in the reaction between AuSac2, a cytotoxic homoleptic gold(I) compound with the saccharinate ligand, and the model protein hen egg white lysozyme
4LGK 2013-10-02 1.96 X-ray structure of the adduct between hen egg white lysozyme and Au2Phen, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers
2LZT 1990-01-15 1.97 REFINEMENT OF TRICLINIC LYSOZYME. II. THE METHOD OF STEREOCHEMICALLY RESTRAINED LEAST-SQUARES
1LZT 1985-07-18 1.97 REFINEMENT OF TRICLINIC LYSOZYME
4WO9 2015-02-18 1.99 Lysozyme Post-Surface Acoustic Waves
6GOI 2018-07-25 1.99 X-ray structure of the adduct formed upon reaction of lysozyme with a Pd(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated triphenylphosphonium cation
4NHS 2014-09-17 1.99 X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (9 days)
4MR1 2014-06-04 1.99 X-ray structure of the adduct between hen egg white lysozyme and cis-diamminediiodoplatinum(II)
4A8B 2012-01-11 13.0 Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes
4A8A 2011-12-28 14.2 Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme
3WPJ 2014-07-30 2.0 SPATIOTEMPORAL DEVELOPMENT of SOAKED PROTEIN CRYSTAL; NATIVE
3ZVQ 2011-10-19 2.0 Crystal Structure of proteolyzed lysozyme
6D6F 2018-09-19 2.0 Triclinic lysozyme cryocooled to 100 K with 47% xylose as cryoprotectant
2YDG 2011-07-20 2.0 Ascorbate co-crystallized HEWL.
2EKS 2008-03-25 2.0 Crystal structure of humanized HyHEL-10 FV-HEN lysozyme complex
2YBI 2011-07-20 2.0 Nitrate X-ray induced reduction on HEWL crystals (6.62 MGy)
1DZB 2000-11-02 2.0 Crystal structure of phage library-derived single-chain Fv fragment 1F9 in complex with turkey egg-white lysozyme
6D6E 2018-09-19 2.0 Triclinic lysozyme (295 K) in the presence of 47% xylose
2YBM 2011-07-20 2.0 Nitrate X-ray induced reduction on HEWL crystals (23.3 MGy)
4LT3 2014-07-23 2.0 HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 2 processed using the XDS software package
1LJI 2002-10-19 2.0 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE 10% SORBITOL
2LYM 1987-10-16 2.0 CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME AT A HYDROSTATIC PRESSURE OF 1000 ATMOSPHERES
2YBJ 2011-07-20 2.0 Nitrate X-ray induced reduction on HEWL crystals (12.31 MGy)
1IO5 2001-02-07 2.0 HYDROGEN AND HYDRATION OF HEN EGG-WHITE LYSOZYME DETERMINED BY NEUTRON DIFFRACTION
1LYZ 1977-04-12 2.0 Real-space refinement of the structure of hen egg-white lysozyme
1ZV5 2006-04-04 2.0 Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme
4WO6 2015-02-18 2.0 Lysozyme Pre-surface acoustic wave
3WU9 2014-07-30 2.0 Spatiotemporal development of soaked protein crystal; derivative 1580 sec
1G7L 2000-11-22 2.0 CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S)
1P2C 2004-02-17 2.0 crystal structure analysis of an anti-lysozyme antibody
5LVG 2016-09-21 2.0 Hen Egg White Lysozyme soaked with cis-Ru(DMSO)4Cl2
5LA8 2016-12-21 2.0 Room temperature X-ray diffraction of tetragonal HEWL. Third data set (0.93 MGy)
6D6H 2018-09-19 2.0 Triclinic lysozyme cryocooled to 100 K with 47% MPD as cryoprotectant
3WU7 2014-07-30 2.0 Spatiotemporal development of soaked protein crystal; derivative 250 sec
4NSG 2014-10-15 2.0 Carboplatin binding to HEWL in NaBr crystallisation conditions studied at an X-ray wavelength of 1.5418A
3WPK 2014-07-30 2.0 SPATIOTEMPORAL DEVELOPMENT of SOAKED PROTEIN CRYSTAL; 750 SEC
5LYZ 1977-04-12 2.0 Real-space refinement of the structure of hen egg-white lysozyme
4IAT 2013-12-11 2.0 HEW Lysozyme by langmuir- blodgett modified vapour diffusion
3WU8 2014-07-30 2.0 Spatiotemporal development of soaked protein crystal; derivative 1080 sec
4GCC 2013-01-02 2.0 Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 1
3WUL 2014-11-05 2.0 Crystal structure of hen egg-white lysozyme
3WUA 2014-07-30 2.0 Spatiotemporal development of soaked protein crystal; derivative 3610 sec
4M4O 2013-12-18 2.0 Crystal structure of the aptamer minE-lysozyme complex
4XJI 2015-06-03 2.0 X-ray structure of LysozymeS2
1LJ3 2002-10-19 2.0 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6
4XJH 2015-06-03 2.0 X-ray structure of LysozymeS1
4G4H 2012-11-07 2.0 100K X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage
2CDS 2003-05-20 2.0 LYSOZYME
4LYZ 1977-04-12 2.0 Real-space refinement of the structure of hen egg-white lysozyme
4G4C 2012-11-07 2.0 Room temperature X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage
3A3Q 2009-11-03 2.0 Structure of N59D HEN EGG-WHITE LYSOZYME in complex with (GlcNAc)3
2DQI 2007-01-23 2.0 Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme
4I8S 2013-11-20 2.0 Hen Lysozyme protein crystallization via standard hanging drop vapor diffusion
1LJE 2002-10-19 2.0 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% SUCROSE
4LT2 2014-07-23 2.0 HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 2 processed using the EVAL software package
2ZQ4 2008-09-30 2.0 The crystal structure of the orthorhombic form of hen egg white lysozyme at 2.0 angstroms resolution
3LYZ 1977-04-12 2.0 Real-space refinement of the structure of hen egg-white lysozyme
2YBN 2011-07-20 2.0 Nitrate X-ray induced reduction on HEWL crystals (28.6 MGy)
4YEN 2015-03-04 2.0 Room temperature X-ray diffraction studies of cisplatin binding to HEWL in DMSO media after 14 months of crystal storage - new refinement
4KXI 2014-05-28 2.0 Crystallographic study of the complex of Ni(II) Schiff base complex and HEW Lysozyme
5GWB 2017-09-13 2.0 Hen Egg White Lysozyme native crystals soaked for 2 hours in precipitant solution containing 1 M guanidine hydrochloride and 25% glycerol, before data collection
1LPI 1998-06-17 2.0 HEW LYSOZYME: TRP...NA CATION-PI INTERACTION
1HSW 1998-08-12 2.0 LYSOZYME (MUCOPEPTIDE N-ACETYLMURAMYL HYDROLASE)
6D6G 2018-09-19 2.0 Triclinic lysozyme (295 K) in the presence of 47% MPD
1PS5 2003-09-09 2.0 STRUCTURE OF THE MONOCLINIC C2 FORM OF HEN EGG-WHITE LYSOZYME AT 2.0 ANGSTROMS RESOLUTION
3WXT 2014-11-05 2.0 Crystal structure of hen egg-white lysozyme
1UCO 1996-07-11 2.0 HEN EGG-WHITE LYSOZYME, LOW HUMIDITY FORM
2YBL 2011-07-20 2.0 Nitrate X-ray induced reduction on HEWL crystals (17.9 MGy)
3WPL 2014-07-30 2.0 SPATIOTEMPORAL DEVELOPMENT of SOAKED PROTEIN CRYSTAL; 2510 SEC
1DKJ 1996-07-11 2.0 BOBWHITE QUAIL LYSOZYME
5B59 2016-09-14 2.0 Hen egg-white lysozyme modified with a keto-ABNO.
1LSZ 1995-01-26 2.0 CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT
1KIR 1996-12-23 2.0 FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
2LYZ 1977-04-12 2.0 Real-space refinement of the structure of hen egg-white lysozyme
3WXU 2014-11-05 2.0 Crystal structure of hen egg-white lysozyme
1LJJ 2002-10-19 2.0 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% TREHALOSE
3LYM 1987-10-16 2.0 CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME AT A HYDROSTATIC PRESSURE OF 1000 ATMOSPHERES
5KKJ 2017-02-15 2.0 2.0-Angstrom In situ Mylar structure of hen egg-white lysozyme (HEWL) at 293 K
6LYZ 1977-04-12 2.0 Real-space refinement of the structure of hen egg-white lysozyme
3WUM 2014-11-05 2.0 Crystal structure of hen egg-white lysozyme
2YBH 2011-07-20 2.0 Nitrate X-ray induced reduction on HEWL crystals (2.31 MGy).
1DQJ 2000-01-19 2.0 CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME
5WRB 2017-12-20 2.01 Crystal structure of hen egg-white lysozyme
1QTK 1999-07-06 2.03 CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF KRYPTON (55 BAR)
1C10 1999-07-22 2.03 CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR)
4LYO 1998-05-27 2.05 CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER
6APM 2018-04-04 2.05 Hen egg-white lysozyme (WT), solved with serial millisecond crystallography using synchrotron radiation
4QY9 2014-11-05 2.05 X-ray structure of the adduct between hen egg white lysozyme and Auoxo3, a cytotoxic gold(III) compound
5UVJ 2017-05-24 2.05 Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation
6GF0 2018-10-17 2.07 Lysozyme structure determined from SFX data using a Sheet-on-Sheet chipless chip
4O34 2014-06-11 2.09 Room temperature macromolecular serial crystallography using synchrotron radiation
4G4B 2012-11-07 2.1 Room temperature X-ray diffraction study of cisplatin binding to HEWL in DMSO media with NAG after 7 months of crystal storage
1IC7 2001-07-18 2.1 CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX
4LT0 2014-07-23 2.1 HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 1 processed using the EVAL software package
1JTT 2001-12-05 2.1 Degenerate interfaces in antigen-antibody complexes
4N5R 2013-11-27 2.1 Hen egg-white lysozyme phased using free-electron laser data
5C6J 2015-07-08 2.1 Crystal Structure of Gadolinium derivative of HEWL solved using Free-Electron Laser radiation
5OB7 2017-07-26 2.1 X-ray structure of the adduct formed upon reaction of lysozyme with the compound fac-[RuII(CO)3Cl2(N3-IM), IM=imidazole (crystal 2)
6H79 2019-03-20 2.1 SSX structure of Lysozyme in flow - metal-kapton microfluidic device
1JPO 1997-11-12 2.1 LOW TEMPERATURE ORTHORHOMBIC LYSOZYME
1XGR 2005-09-06 2.1 Structure for antibody HyHEL-63 Y33I mutant complexed with hen egg lysozyme
1KIP 1996-12-23 2.1 FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
1NDM 2003-06-03 2.1 Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme
4YOP 2015-12-23 2.1 CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME
1XEJ 1998-04-29 2.1 THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION
3AZ7 2012-05-09 2.1 Crystal structure of Pt/T-HEWL
3P65 2011-02-09 2.1 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme
1XGU 2005-09-06 2.1 Structure for antibody HyHEL-63 Y33F mutant complexed with hen egg lysozyme
4LFX 2013-10-02 2.1 X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers
1XGP 2005-09-06 2.1 Structure for antibody HyHEL-63 Y33A mutant complexed with hen egg lysozyme
5C6L 2015-07-08 2.1 Crystal Structure of Gadolinium derivative of HEWL solved using intense Free-Electron Laser radiation
3AW7 2011-03-30 2.1 Crystal structure of tetragonal hen egg white lysozyme at 71.9% relative humidity
3AW6 2011-03-30 2.1 Crystal structure of tetragonal hen egg white lysozyme at 84.2% relative humidity
4X3B 2015-06-10 2.1 A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering
1LJK 2002-10-19 2.1 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 15% TREHALOSE
1XGT 2005-09-06 2.1 Structure for antibody HyHEL-63 Y33L mutant complexed with hen egg lysozyme
1XEI 1998-04-29 2.1 THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION
1XGQ 2005-09-06 2.1 Structure for antibody HyHEL-63 Y33V mutant complexed with hen egg lysozyme
2D91 2006-07-11 2.1 Structure of HYPER-VIL-lysozyme
1GHL 1993-10-31 2.1 THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES
4LYM 1991-10-15 2.1 CRYSTAL STRUCTURE OF LOW HUMIDITY TETRAGONAL LYSOZYME AT 2.1-ANGSTROMS RESOLUTION. VARIABILITY IN HYDRATION SHELL AND ITS STRUCTURAL CONSEQUENCES
4NSH 2014-10-15 2.1 Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6
4YM8 2015-12-23 2.1 Crystal structure of hen egg-white lysozyme
5O4X 2017-08-23 2.11 Protein structure determination by electron diffraction using a single three-dimensional nanocrystal
5O4W 2017-08-23 2.11 Protein structure determination by electron diffraction using a single three-dimensional nanocrystal
5F81 2016-02-10 2.13 Acoustic injectors for drop-on-demand serial femtosecond crystallography
4OOO 2014-06-18 2.15 X-ray structure of the lysozyme derivative of tetrakis(acetato)chlorido diruthenium(II,III) complex
4Z3M 2015-09-02 2.15 X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Complex with S,O Bidentate Ligands (9b)
4TTD 2015-07-08 2.15 Structure of a lysozyme antibody complex
4RLN 2015-02-25 2.17 Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with nXDS
5OCV 2018-03-28 2.2 A Rare Lysozyme Crystal Form Solved Using High-Redundancy 3D Electron Diffraction Data from Micron-Sized Needle Shaped Crystals
2LZ2 1989-10-15 2.2 THE THREE DIMENSIONAL STRUCTURE OF TURKEY EGG WHITE LYSOZYME AT 2.2 ANGSTROMS RESOLUTION
6H0K 2018-09-05 2.2 Hen egg-white lysozyme structure determined with data from the EuXFEL, the first MHz free electron laser, 7.47 keV photon energy
4PRU 2014-11-12 2.2 Crystal structure of dimethyllysine hen egg-white lysozyme in complex with sclx4 at 2.2 A resolution
3G3A 2009-06-23 2.2 Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen
3T6U 2011-08-24 2.21 Crystal Structure of Lysozyme in 40% sucrose
4N1E 2014-10-29 2.23 Structural evidence for antigen receptor evolution
5E9R 2016-10-26 2.25 X-ray structure of the complex between lysozyme and the compound fac, cis-[RuII(CO)3Cl2(N3-MBI), MBI=N-methyl-benzimidazole
6GOJ 2018-07-25 2.25 X-ray structure of the adduct formed upon reaction of lysozyme with a Pt(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated triphenylphosphonium cation
4U3X 2015-03-11 2.26 Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme
4TSA 2015-07-08 2.27 Structure of a lysozyme FAb complex
5OP1 2018-08-29 2.28 Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme
2ZNX 2009-01-27 2.3 5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme
4HV1 2013-11-20 2.3 Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains (lb4)
4H1P 2012-10-24 2.3 Use of Europium for SAD Phasing at the Cu K alpha wavelength
3B6L 2008-07-01 2.3 Crystal structure of lysozyme folded in SDS and 2-methyl-2,4-pentanediol
1XEK 1998-04-29 2.3 THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION
4NSI 2014-10-15 2.3 Carboplatin binding to HEWL in 20% propanol, 20% PEG 4000 at pH5.6
2DQG 2007-01-23 2.3 Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme
1IC5 2001-07-18 2.3 CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX
4LT1 2014-07-23 2.3 HEWL co-crystallised with Carboplatin in non-NaCl conditions: crystal 1 processed using the XDS software package
5JEN 2016-09-07 2.3 Crystal structure of the anti-sigma factor RsiV bound to lysozyme
5B1F 2016-12-07 2.3 Crystal structure of hen egg-white lysozyme
5DM9 2016-04-13 2.3 XFEL structure of hen egg-white lysozyme solved using a droplet injector at SACLA
4RW2 2015-05-20 2.3 Hen egg-white lysozyme structure from a spent-beam experiment at LCLS: refocused beam
2DQH 2007-01-23 2.3 Crystal structure of hyhel-10 FV mutant (Hy58a) complexed with hen egg lysozyme
5B1G 2016-12-07 2.3 Crystal structure of hen egg-white lysozyme
1C08 2000-07-19 2.3 CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN LYSOZYME COMPLEX
3AZ5 2012-05-09 2.34 Crystal structure of Pt/O-HEWL
3M3U 2010-03-23 2.35 Effect of temperature on tryptophan fluorescence in lysozyme crystals
5OB9 2017-07-26 2.38 X-ray structure of the adduct formed upon reaction of lysozyme with the compound fac-[RuII(CO)3Cl2(N3-MIM), MIM=methyl-imidazole (crystals grown using ethylene glycol
1LSG 1995-09-15 2.4 THREE-DIMENSIONAL STRUCTURE OF THE PLATELET INTEGRIN RECOGNITION SEGMENT OF THE FIBRINOGEN GAMMA CHAIN OBTAINED BY CARRIER PROTEIN-DRIVEN CRYSTALLIZATION
4G49 2012-11-07 2.4 Room temperature X-ray diffraction of cisplatin binding to HEWL in aqueous media after 15 months of crystal storage
3WUN 2015-05-27 2.4 Crystal structure of hen egg-white lysozyme
3G3B 2009-06-23 2.4 Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen
1JHL 1994-01-31 2.4 THREE-DIMENSIONAL STRUCTURE OF A HETEROCLITIC ANTIGEN-ANTIBODY CROSS-REACTION COMPLEX
2YSS 2008-04-08 2.4 Crystal structure of Humanized HYHEL-10 FV mutant(HQ39KW47Y)-HEN lysozyme complex
5HNL 2016-07-20 2.42 In-house X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels
6GOH 2018-07-25 2.43 X-ray structure of the adduct formed upon reaction of lysozyme with a Pt(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated sulphonate side chain
4DDA 2012-04-25 2.48 EVAL processed HEWL, NAG
3TXJ 2013-01-30 2.48 HEWL co-crystallization with NAG with silicone oil as the cryoprotectant
8LYZ 1977-10-24 2.5 AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME
9LYZ 1980-02-27 2.5 X-RAY CRYSTALLOGRAPHY OF THE BINDING OF THE BACTERIAL CELL WALL TRISACCHARIDE NAM-NAG-NAM TO LYSOZYME
2DQF 2007-01-23 2.5 Crystal structure of hyhel-10 FV mutant (y33ay53a) complexed with hen egg lysozyme
5A3E 2015-06-17 2.5 2.5A structure of lysozyme determined by MicroED with data from a single crystal
1MEL 1997-06-16 2.5 CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME
3F6Z 2008-12-23 2.5 Crystal structure of Pseudomonas aeruginosa MliC in complex with hen egg white lysozyme
7LYZ 1977-06-20 2.5 PROTEIN MODEL BUILDING BY THE USE OF A CONSTRAINED-RESTRAINED LEAST-SQUARES PROCEDURE
1FDL 1991-10-15 2.5 CRYSTALLOGRAPHIC REFINEMENT OF THE THREE-DIMENSIONAL STRUCTURE OF THE FAB D1.3-LYSOZYME COMPLEX AT 2.5-ANGSTROMS RESOLUTION
3LZ2 1993-10-31 2.5 STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION
2EPE 2007-04-17 2.5 Crystal structure analysis of Hen egg white lysozyme grown by capillary method
4WMG 2015-04-22 2.5 Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A)
4HV2 2013-11-20 2.5 Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains (lb5)
1MLC 1995-06-03 2.5 MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME
2I26 2007-03-06 2.5 Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme
1IC4 2001-07-18 2.5 CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX
3J6K 2014-08-13 2.5 2.5A structure of lysozyme solved by MicroED
1JTO 2001-10-31 2.5 Degenerate interfaces in antigen-antibody complexes
4QGZ 2014-07-30 2.51 X-ray structure of the adduct formed between hen egg white lysozyme and trans-dimethylamine methylamine dichlorido platinum(II)
5J7C 2016-08-17 2.54 A picomolar affinity FN3 domain in complex with hen egg-white lysozyme
4GLV 2013-08-21 2.57 OBody AM3L09 bound to hen egg-white lysozyme
6HT2 2019-01-23 2.6 STRUCTURE OF HEWL BY ELECTRON DIFFRACTION AND MICROFOCUS DIFFRACTION
4IAS 2013-12-11 2.6 HEW Lysozyme by langmuir- blodgett modified vapour diffusion
4PGJ 2015-03-11 2.6 Human heavy-chain domain antibody in complex with hen egg-white lysozyme
1BQL 1995-04-20 2.6 STRUCTURE OF AN ANTI-HEL FAB FRAGMENT COMPLEXED WITH BOBWHITE QUAIL LYSOZYME
4DC4 2013-01-23 2.65 Lysozyme Trimer
2IFF 1994-05-31 2.65 STRUCTURE OF AN ANTIBODY-LYSOZYME COMPLEX: EFFECT OF A CONSERVATIVE MUTATION
4M6D 2013-12-11 2.68 Crystal structure of the aptamer minF-lysozyme complex.
1BVK 1999-02-16 2.7 HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME
2ZNW 2009-01-27 2.71 Crystal Structure of ScFv10 in Complex with Hen Egg Lysozyme
4GLA 2013-08-14 2.75 OBody NL8 bound to hen egg-white lysozyme
4GCD 2013-01-02 2.8 Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 2
1LZ2 1981-12-08 2.8 CRYSTALLOGRAPHIC STUDY OF TURKEY EGG-WHITE LYSOZYME AND ITS COMPLEX WITH A DISACCHARIDE
6HU5 2019-01-23 2.8 STRUCTURE OF HEWL BY ELECTRON DIFFRACTION AND MICROFOCUS DIFFRACTION
1JA2 2001-06-15 2.87 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY
3MBE 2010-05-12 2.89 TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27)
3J4G 2013-11-13 2.9 Structure of lysozyme solved by MicroED to 2.9 A
4GCE 2013-01-02 2.9 Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3
1JA4 2001-06-15 2.94 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY
1JA6 2001-06-15 2.96 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY
1JA7 2001-06-15 2.98 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY
3HFM 1989-07-12 3.0 STRUCTURE OF AN ANTIBODY-ANTIGEN COMPLEX. CRYSTAL STRUCTURE OF THE HY/HEL-10 FAB-LYSOZYME COMPLEX
3TXK 2013-01-30 3.0 HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant at pH 6.5
1ZMY 2005-10-04 3.0 cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme
4DDB 2012-04-25 3.0 EVAL processed HEWL, cisplatin DMSO paratone pH 6.5
1FBI 1995-02-27 3.0 CRYSTAL STRUCTURE OF A CROSS-REACTION COMPLEX BETWEEN FAB F9.13.7 AND GUINEA-FOWL LYSOZYME
1F3J 2000-09-20 3.1 HISTOCOMPATIBILITY ANTIGEN I-AG7
1XFT 2005-04-05 3.35 Synchrotron X-ray Powder Diffraction Study of Hexagonal Turkey Egg-white Lysozyme
4GCF 2013-01-02 3.5 Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 4
3OTP 2011-01-19 3.76 Crystal structure of the DegP dodecamer with a model substrate
1BHZ 1998-11-04 3.9 LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF HEN EGG WHITE LYSOZYME FROM MASC DATA
1LZH 1981-09-28 6.0 THE STRUCTURES OF THE MONOCLINIC AND ORTHORHOMBIC FORMS OF HEN EGG-WHITE LYSOZYME AT 6 ANGSTROMS RESOLUTION.
2LZH 1981-09-28 6.0 THE STRUCTURES OF THE MONOCLINIC AND ORTHORHOMBIC FORMS OF HEN EGG-WHITE LYSOZYME AT 6 ANGSTROMS RESOLUTION.

Relevant UniProtKB Entries

Percent Identity Matching Chains Protein Accession Entry Name
92.3 Lysozyme C P49663 LYSC_PHAVE
93.0 Lysozyme C P81711 LYSC_SYRSO
93.2 Lysozyme C P00702 LYSC_PHACO
94.6 Lysozyme C P24533 LYSC_SYRRE
93.0 Lysozyme C P24364 LYSC_LOPLE
95.2 Lysozyme C P00703 LYSC_MELGA
95.3 Lysozyme C Q7LZT2 LYSC_TRATE
95.3 Lysozyme C P22910 LYSC_CHRAM
94.6 Lysozyme C P00704 LYSC_NUMME
96.1 Lysozyme C P19849 LYSC_PAVCR
95.3 Lysozyme C P00701 LYSC_COTJA
96.1 Lysozyme C Q7LZI3 LYSC_TRASA
96.9 Lysozyme C Q7LZP9 LYSC_LOPIM
96.9 Lysozyme C Q7LZQ0 LYSC_CATWA
99.2 Lysozyme C P00699 LYSC_CALCC
99.2 Lysozyme C P00700 LYSC_COLVI
100.0 Lysozyme C P00698 LYSC_CHICK