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Analysis of paper: A comprehensive biophysical description of pairwise epistasis throughout an entire protein domain

Abstract

Calculated ddG screen as described in 'Olson CA;Wu NC;Sun R,Curr Biol (2014) A comprehensive biophysical description of pairwise epistasis throughout an entire protein domain' to compare to other biophysical measurements in the literature

Submission Details

ID: T2CDCEr8

Submitter: Connie Wang

Submission Date: Nov. 1, 2017, 4:34 p.m.

Version: 4

Publication Details

Wang CW (2017-10-27) Analysis of paper: A comprehensive biophysical description of pairwise epistasis throughout an entire protein domain; unpublished work from Protabit group

Additional Information

Study Summary

Number of data points	1966
Proteins	Immunoglobulin G-binding protein G
Unique complexes	1038
Assays/Quantities/Protocols	Experimental Assay: ddG_screen ; Experimental Assay: ln W
Libraries	Fitness for single mutants ; ddG screen calculation from double mutants of 1PGA

Structure view and single mutant data analysis

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Study data

Colors:	D	E	R	H	K	S	T	N	Q	A	V	I	L	M	F	Y	W	C	G	P

Data Distribution

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Relevant PDB Entries

Structure ID	Release Date	Resolution	Structure Title

Relevant UniProtKB Entries

Percent Identity	Matching Chains	Protein	Accession	Entry Name
100.0		Immunoglobulin G-binding protein G	P06654	SPG1_STRSG
100.0		Immunoglobulin G-binding protein G	P19909	SPG2_STRSG