Three-state denaturation of alpha-lactalbumin by guanidine hydrochloride.


Abstract

Study holds ProTherm entries: 11249 Extra Details: transition curves; intermediate; cotton effects;,acid form; tertiary structure

Submission Details

ID: FFbjJ6pX4

Submitter: Connie Wang

Submission Date: April 24, 2018, 8:41 p.m.

Version: 1

Publication Details
Kuwajima K;Nitta K;Yoneyama M;Sugai S,J. Mol. Biol. (1976) Three-state denaturation of alpha-lactalbumin by guanidine hydrochloride. PMID:10445
Additional Information

Structure view and single mutant data analysis

Study data

No weblogo for data of varying length.
Colors: D E R H K S T N Q A V I L M F Y W C G P
 

Data Distribution

Studies with similar sequences (approximate matches)

Correlation with other assays (exact sequence matches)


Relevant PDB Entries

Structure ID Release Date Resolution Structure Title
1F6R 2000-06-23T00:00:00+0000 2.2 CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN
1F6S 2000-06-23T00:00:00+0000 2.2 CRYSTAL STRUCTURE OF BOVINE ALPHA-LACTALBUMIN
1FKQ 2000-08-10T00:00:00+0000 1.8 RECOMBINANT GOAT ALPHA-LACTALBUMIN T29V
1FKV 2000-08-10T00:00:00+0000 2.0 RECOMBINANT GOAT ALPHA-LACTALBUMIN T29I
1HFY 1996-06-13T00:00:00+0000 2.3 ALPHA-LACTALBUMIN
1HFZ 1996-06-13T00:00:00+0000 2.3 ALPHA-LACTALBUMIN
1HMK 1998-11-26T00:00:00+0000 2.0 RECOMBINANT GOAT ALPHA-LACTALBUMIN
2G4N 2006-02-22T00:00:00+0000 2.3 Anomalous substructure of alpha-lactalbumin
3B0K 2011-06-10T00:00:00+0000 1.6 Crystal structure of alpha-lactalbumin
6IP9 2018-11-02T00:00:00+0000 1.85 Crystal Structure of Lanthanum ion (La3+) bound bovine alpha-lactalbumin

Relevant UniProtKB Entries

Percent Identity Matching Chains Protein Accession Entry Name
95.1 Alpha-lactalbumin P00712 LALBA_CAPHI
97.2 Alpha-lactalbumin P09462 LALBA_SHEEP
98.6 Alpha-lactalbumin Q9TSN6 LALBA_BUBBU
99.3 Alpha-lactalbumin Q9TSR4 LALBA_BOSMU
100.0 Alpha-lactalbumin P00711 LALBA_BOVIN