Effects of ions and pH on the thermal stability of thin and thick filaments of skeletal muscle: high-sensitivity differential scanning calorimetric study.


Abstract

Differential scanning calorimetry (DSC) is unique for studying conformational changes in supramolecular structures because it is immune to interference by the turbidity and other optical artifacts of a sample solution. We have employed DSC to study thermal stability of myosin and actin in their filamentous forms (i.e., thick and thin filaments). The thermal stability of the myosin monomer, as well as polymers, showed remarkable sensitivities to pH and to the ionic strength of the solution. At pH 7.5, the endotherm of myosin filaments was broad and resembled that of the monomer in solution. Reducing the pH to 6.3 split the endotherm of the filament into two major transitions. The first one, with a Tm of 47 degrees C, a delta Hcal of 805 kcal/mol, and a cooperative ratio (CR) of 0.1, was relatively insensitive to the pH changes whereas the second one which represented approximately 80% of the helical structure was pH sensitive. The second transition released 2.17 H+ per mole at 0.17 M KCl and was defined by a Tm of 53.9 degrees C, a delta Hcal of 917 kcal/mol, and a CR of 0.35. The major fragment contributing to the splitting of the endotherm was interpreted to be S-2 because the Tm of purified S-2 in a similar medium also shifted from 39.5 degrees C at pH 7.3 to 49.6 degrees C at pH 6.0. KCl had similar effects on the shape of the endotherm of the thick filament. A decrease of KCl from 0.2 to 0.1 M enhanced the effect of pH on the second transition.(ABSTRACT TRUNCATED AT 250 WORDS) Study holds ProTherm entries: 4003, 4004, 4005, 4006, 4007, 4008, 4009, 4010, 4011, 4012, 4013, 10610, 10611, 10612, 10613, 10614, 10615, 10616, 10617, 10618, 10619, 10620, 10621, 10622, 10623, 10624, 10625, 10626, 10627, 10628, 10629, 10630, 10631, 10632, 10633, 10634, 10635, 10636, 10637, 10638, 10639, 10640, 10641, 10642, 10643, 10644, 10645, 10646, 10647, 10648, 10649, 10650, 10651, 10652, 10653, 10654, 10655, 10656, 10657, 10658, 10659, 10660, 10661, 10662, 10663 Extra Details: additive : EDTA(1 mM),the transition is from native to intermediate supramolecular structures ; thick and thin filaments; actin;,myosin ; cooperativity

Submission Details

ID: AjdAxpQE3

Submitter: Connie Wang

Submission Date: April 24, 2018, 8:24 p.m.

Version: 1

Publication Details
Bertazzon A;Tsong TY,Biochemistry (1990) Effects of ions and pH on the thermal stability of thin and thick filaments of skeletal muscle: high-sensitivity differential scanning calorimetric study. PMID:2207085
Additional Information

Study Summary

Number of data points 135
Proteins Calmodulin ; Myosin light chain kinase 2, skeletal/cardiac muscle ; Actin, alpha skeletal muscle ; Actin, alpha skeletal muscle
Unique complexes 2
Assays/Quantities/Protocols Experimental Assay: dHcal ionic:: , buffers:HEPES: 2 mM, pH:7.9, details:Additives Na-ATP (1.0 mM),, prot_conc:- ; Experimental Assay: Tm pH:7.9, buffers:HEPES: 2 mM, ionic:: , details:Additives Na-ATP (1.0 mM),, prot_conc:- ; Experimental Assay: dHvH ionic:: , details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, pH:7.9, prot_conc:- ; Experimental Assay: dHcal details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, ionic:: , pH:7.6, prot_conc:- ; Experimental Assay: Tm details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, ionic:: , pH:7.6, prot_conc:- ; Experimental Assay: dHvH ionic:: , buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:7.6, prot_conc:- ; Experimental Assay: dHcal details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, ionic:: , pH:7.3, prot_conc:- ; Experimental Assay: Tm details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, ionic:: , pH:7.3, prot_conc:- ; Experimental Assay: dHvH ionic:: , buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:7.3, prot_conc:- ; Experimental Assay: dHcal details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, ionic:: , pH:6.9, prot_conc:- ; Experimental Assay: Tm details:Additives Na-ATP (1.0 mM),, buffers:HEPES: 2 mM, ionic:: , pH:6.9, prot_conc:- ; Experimental Assay: dHvH ionic:: , buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:6.9, prot_conc:- ; Experimental Assay: dHcal ionic:: , buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:6.4, prot_conc:- ; Experimental Assay: Tm ionic:: , buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:6.4, prot_conc:- ; Experimental Assay: dHvH ionic:: , buffers:HEPES: 2 mM, pH:6.4, details:Additives Na-ATP (1.0 mM),, prot_conc:- ; Experimental Assay: dHcal prot_conc:-, buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:5.9, ionic:: 2 mM,50 ; Experimental Assay: Tm prot_conc:-, buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:5.9, ionic:: 2 mM,50 mM ; Experimental Assay: dHvH prot_conc:-, buffers:HEPES: 2 mM, details:Additives Na-ATP (1.0 mM),, pH:5.9, ionic:: 2 mM,50 m ; Experimental Assay: dHcal pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 8.0 mM, prot_conc ; Experimental Assay: Tm pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 8.0 mM, prot_conc:- ; Experimental Assay: dHvH pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 8.0 mM, prot_conc: ; Experimental Assay: dHcal ionic:Ca2+: 4.0 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc ; Experimental Assay: Tm ionic:Ca2+: 4.0 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc:- ; Experimental Assay: dHvH ionic:Ca2+: 4.0 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc: ; Experimental Assay: dHcal prot_conc:-, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 2.0 ; Experimental Assay: Tm prot_conc:-, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 2.0 mM ; Experimental Assay: dHvH prot_conc:-, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 2.0 m ; Experimental Assay: dHcal ionic:Ca2+: 1.0 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc ; Experimental Assay: Tm ionic:Ca2+: 1.0 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc:- ; Experimental Assay: dHvH ionic:Ca2+: 1.0 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc: ; Experimental Assay: dHcal ionic:Ca2+: 0.4 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc ; Experimental Assay: Tm ionic:Ca2+: 0.4 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc:- ; Experimental Assay: dHvH ionic:Ca2+: 0.4 mM, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, prot_conc: ; Experimental Assay: dHcal prot_conc:-, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 0.2 ; Experimental Assay: Tm prot_conc:-, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 0.2 mM ; Experimental Assay: dHvH prot_conc:-, pH:7.0, details:Additives Na-ATP (0.2 mM),, buffers:HEPES: 2 mM, ionic:Ca2+: 0.2 m ; Experimental Assay: dHcal buffers:potassium phosphate: 20 mM, pH:7.0, prot_conc:-, ionic:KCl: 0.17 M, details:Additives ; Experimental Assay: dHvH buffers:potassium phosphate: 20 mM, pH:7.0, prot_conc:-, ionic:KCl: 0.17 M, details:Additives E ; Experimental Assay: dHcal pH:6.7, buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, details:Additives ; Experimental Assay: dHvH pH:6.7, buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, details:Additives E ; Experimental Assay: dHcal buffers:potassium phosphate: 20 mM, pH:6.5, prot_conc:-, ionic:KCl: 0.17 M, details:Additives ; Experimental Assay: dHvH buffers:potassium phosphate: 20 mM, pH:6.5, prot_conc:-, ionic:KCl: 0.17 M, details:Additives E ; Experimental Assay: dHcal buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, pH:6.3, details:Additives ; Experimental Assay: dHvH buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, pH:6.3, details:Additives E ; Experimental Assay: dHcal pH:6.7, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives ; Experimental Assay: dHvH pH:6.7, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives E ; Experimental Assay: dHcal pH:6.5, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives ; Experimental Assay: dHvH pH:6.5, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives E ; Experimental Assay: dHcal prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.3, ionic:KCl: 0.15 M, details:Additives ; Experimental Assay: dHvH prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.3, ionic:KCl: 0.15 M, details:Additives E ; Experimental Assay: Tm ionic:KCl: 0.25 M, prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.3, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.20 M, prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.3, details:Additives EDT ; Experimental Assay: Tm buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, pH:6.3, details:Additives EDT ; Experimental Assay: Tm prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.3, ionic:KCl: 0.15 M, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.13 M, prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.3, details:Additives EDT ; Experimental Assay: Tm prot_conc:-, details:Additives EDTA (1 mM),, buffers:potassium phosphate: 20 mM, pH:6.3, ionic:KC ; Experimental Assay: Tm ionic:KCl: 0.25 M, pH:6.5, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.20 M, prot_conc:-, buffers:potassium phosphate: 20 mM, pH:6.5, details:Additives EDT ; Experimental Assay: Tm buffers:potassium phosphate: 20 mM, pH:6.5, prot_conc:-, ionic:KCl: 0.17 M, details:Additives EDT ; Experimental Assay: Tm pH:6.5, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.13 M, pH:6.5, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm pH:6.5, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.10 M, details:Additives EDT ; Experimental Assay: Tm prot_conc:-, ionic:KCl: 0.25 M, details:Additives EDTA (1 mM),, buffers:potassium phosphate: 20 m ; Experimental Assay: Tm pH:6.7, ionic:KCl: 0.20 M, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm pH:6.7, buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, details:Additives EDT ; Experimental Assay: Tm pH:6.7, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.13 M, pH:6.7, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm pH:6.7, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.10 M, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.25 M, pH:7.0, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm pH:7.0, ionic:KCl: 0.20 M, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm buffers:potassium phosphate: 20 mM, pH:7.0, prot_conc:-, ionic:KCl: 0.17 M, details:Additives EDT ; Experimental Assay: Tm pH:7.0, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives EDT ; Experimental Assay: Tm ionic:KCl: 0.13 M, pH:7.0, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm pH:7.0, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.10 M, details:Additives EDT ; Experimental Assay: Tm pH:7.5, buffers:potassium phosphate: 20 mM, prot_conc:-, ionic:KCl: 0.17 M, details:Additives EDT ; Experimental Assay: Tm pH:7.5, prot_conc:-, buffers:potassium phosphate: 20 mM, ionic:KCl: 0.15 M, details:Additives EDT ; Experimental Assay: Tm pH:7.5, ionic:KCl: 0.13 M, prot_conc:-, buffers:potassium phosphate: 20 mM, details:Additives EDT ; Experimental Assay: Tm buffers:Potassium phosphate: 20 mM, ionic:: , pH:7.3, details:Additives EDTA (1 mM), ; Experimental Assay: Tm pH:6.8, buffers:Potassium phosphate: 20 mM, ionic:: , details:Additives EDTA (1 mM), ; Experimental Assay: Tm buffers:Potassium phosphate: 20 mM, ionic:: , pH:5.9, details:Additives EDTA (1 mM), ; Experimental Assay: dHcal prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, pH:7.0, buffers:Potassium phosphate: 20 mM, detail ; Experimental Assay: Tm prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, pH:7.0, buffers:Potassium phosphate: 20 mM, details:A ; Experimental Assay: dHvH prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, pH:7.0, buffers:Potassium phosphate: 20 mM, details ; Experimental Assay: dHcal prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, details:Additives EDTA (1 mM),, buffers:Potassium ; Experimental Assay: Tm prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, details:Additives EDTA (1 mM),, buffers:Potassium pho ; Experimental Assay: dHvH prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, details:Additives EDTA (1 mM),, buffers:Potassium p ; Experimental Assay: dHcal prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, pH:6.5, buffers:Potassium phosphate: 20 mM, detail ; Experimental Assay: Tm prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, pH:6.5, buffers:Potassium phosphate: 20 mM, details:A ; Experimental Assay: dHvH prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, pH:6.5, buffers:Potassium phosphate: 20 mM, details ; Experimental Assay: dHcal prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, buffers:Potassium phosphate: 20 mM, pH:6.3, detail ; Experimental Assay: Tm prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, buffers:Potassium phosphate: 20 mM, pH:6.3, details:A ; Experimental Assay: dHvH prot_conc:1.8-3.5 mg/ml, ionic:KCl: 0.13 M, buffers:Potassium phosphate: 20 mM, pH:6.3, details
Libraries Mutations for sequence A:DEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHR/D:LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCGNCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT ; Mutations for sequence A:ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK/B:KRRWKKNFIAVSAANRFKKISSSGAL

Structure view and single mutant data analysis

Study data

No weblogo for data of varying length.
Colors: D E R H K S T N Q A V I L M F Y W C G P
 

Data Distribution

Studies with similar sequences (approximate matches)

Correlation with other assays (exact sequence matches)


Relevant PDB Entries

Structure ID Release Date Resolution Structure Title
1SW8 2004-04-06 Solution structure of the N-terminal domain of Human N60D calmodulin refined with paramagnetism based strategy
2LL6 2012-05-16 Solution NMR structure of CaM bound to iNOS CaM binding domain peptide
2K3S 2008-05-27 HADDOCK-derived structure of the CH-domain of the smoothelin-like 1 complexed with the C-domain of apocalmodulin
2DFS 2006-04-25 3-D structure of Myosin-V inhibited state
1NWD 2003-04-08 Solution Structure of Ca2+/Calmodulin bound to the C-terminal Domain of Petunia Glutamate Decarboxylase
5OEO 2018-04-25 Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant
2LL7 2012-05-16 Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide
2MES 2014-12-24 Backbone 1H, 13C, 15N resonance assignments of calcium-bound calmodulin in complex with PSD95 N-terminal peptide
1CMF 1995-12-07 NMR SOLUTION STRUCTURE OF APO CALMODULIN CARBOXY-TERMINAL DOMAIN
5J8H 2016-09-07 Structure of calmodulin in a complex with a peptide derived from a calmodulin-dependent kinase
2M55 2013-05-08 NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin
1NKF 1999-02-16 CALCIUM-BINDING PEPTIDE, NMR, 30 STRUCTURES
1CFF 1999-09-24 NMR SOLUTION STRUCTURE OF A COMPLEX OF CALMODULIN WITH A BINDING PEPTIDE OF THE CA2+-PUMP
2LGF 2012-06-13 Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of L-selectin
5T0X 2017-02-15 Solution NMR-derived structure of calmodulin bound with ER alpha peptides
1CMG 1995-12-07 NMR SOLUTION STRUCTURE OF CALCIUM-LOADED CALMODULIN CARBOXY-TERMINAL DOMAIN
2K0J 2009-03-10 Solution structure of CaM complexed to DRP1p
5J7J 2017-10-25 NMR Derived Structure of Ca2+ Calmodulin bound to Phosphorylated PSD-95
2M3S 2013-07-24 Calmodulin, i85l, f92e, h107i, l112r, a128t, m144r mutant
2BBM 1994-01-31 SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR
2W4U 2010-08-25 Isometrically contracting insect asynchronous flight muscle quick frozen after a length step
2KUH 2010-03-09 Halothane binds to druggable sites in calcium-calmodulin: Solution structure of halothane-CaM C-terminal domain
1X02 2006-03-07 Solution structure of stereo array isotope labeled (SAIL) calmodulin
2K0E 2008-06-10 A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction
1F71 2000-09-22 REFINED SOLUTION STRUCTURE OF CALMODULIN C-TERMINAL DOMAIN
6BUT 2019-06-19 Solution structure of full-length apo mammalian calmodulin bound to the IQ motif of the human voltage-gated sodium channel NaV1.2
2M0K 2013-10-30 3D Structure of Calmodulin and Calmodulin Binding Domain of Rat Olfactory Cyclic Nucleotide-Gated Ion Channel
2L53 2011-01-05 Solution NMR Structure of apo-calmodulin in complex with the IQ motif of Human Cardiac Sodium Channel NaV1.5
1AK8 1997-09-17 NMR SOLUTION STRUCTURE OF CERIUM-LOADED CALMODULIN AMINO-TERMINAL DOMAIN (CE2-TR1C), 23 STRUCTURES
1CFC 1995-12-07 CALCIUM-FREE CALMODULIN
1F70 2000-09-22 REFINED SOLUTION STRUCTURE OF CALMODULIN N-TERMINAL DOMAIN
2KNE 2009-11-24 Calmodulin wraps around its binding domain in the plasma membrane CA2+ pump anchored by a novel 18-1 motif
2LQP 2012-06-06 NMR solution structure of the Ca2+-Calmodulin C-terminal domain in a complex with a peptide (NSCaTE) from the L-type Voltage-Gated Calcium Channel alpha1C subunit
2RRT 2011-05-25 Solution structure of Magnesium-bound form of calmodulin C-domain E104D/E140D mutant
2JZI 2009-01-13 Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin
1SY9 2005-04-12 Structure of calmodulin complexed with a fragment of the olfactory CNG channel
2MG5 2014-03-05 Solution Structure of Calmodulin bound to the target peptide of Endothelial Nitrogen Oxide Synthase phosphorylated at Thr495
2BBN 1994-01-31 SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR
2W49 2010-05-05 ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
2N27 2016-07-06 Competitive inhibition of TRPV1 calmodulin interaction by vanilloids
2KUG 2010-03-09 Halothane binds to druggable sites in calcium-calmodulin: Solution Structure of halothane-CaM N-terminal domain
2LLO 2012-02-01 Solution NMR-derived structure of calmodulin N-lobe bound with ER alpha peptide
1CKK 1999-09-10 CALMODULIN/RAT CA2+/CALMODULIN DEPENDENT PROTEIN KINASE FRAGMENT
2N6A 2015-08-26 NMR structure of a human calmodulin/connexin-36 peptide hybrid
2HF5 2007-05-01 The structure and function of a novel two-site calcium-binding fragment of calmodulin
2L7L 2011-05-18 Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of calmodulin kinase I
5TP6 2017-09-27 Solution structure of the CaM34 with the iNOS CaM binding domain peptide
5TP5 2017-09-27 Solution structure of the calcium deficient mutant calmodulin CaM1234
1MUX 1998-10-14 SOLUTION NMR STRUCTURE OF CALMODULIN/W-7 COMPLEX: THE BASIS OF DIVERSITY IN MOLECULAR RECOGNITION, 30 STRUCTURES
6GDL 2018-10-17 Calmodulin mutant - F141L apo-form Unstructured C-domain
2LLQ 2012-02-01 Solution nmr-derived structure of calmodulin c-lobe bound with er alpha peptide
2KZ2 2011-04-20 Calmodulin, C-terminal domain, F92E mutant
2M0J 2013-10-30 3D Structure of Calmodulin and Calmodulin binding domain of Olfactory cyclic nucleotide-gated ion channel complex
5GGM 2016-09-28 The NMR structure of calmodulin in CTAB reverse micelles
2K61 2009-05-05 Solution structure of CaM complexed to DAPk peptide
2MGU 2014-02-12 Structure of the complex between calmodulin and the binding domain of HIV-1 matrix protein
2LQC 2012-06-06 NMR solution structure of a Ca2+-Calmodulin with a binding motif (NSCaTE) peptide from the N-terminal cytoplasmic domain of the L-type Voltage-Cated Calcium Channel alpha1C subunit
2KDU 2009-12-15 Structural basis of the Munc13-1/Ca2+-Calmodulin interaction: A novel 1-26 calmodulin binding motif with a bipartite binding mode
6FEG 2018-02-21 Solution Structure of CaM/Kv7.2-hAB Complex
2N8J 2016-10-12 Structure and 15N relaxation data of Calmodulin bound to the endothelial Nitric Oxide Synthase Calmodulin Binding Domain Peptide at Physiological Calcium Concentration
3B5U 2008-04-15 Actin filament model from extended form of acromsomal bundle in the Limulus sperm
2LV6 2013-02-20 The complex between Ca-Calmodulin and skeletal muscle myosin light chain kinase from combination of NMR and aqueous and contrast-matched SAXS data
6FEH 2018-02-21 Solution Structure of CaM/Kv7.2-hAB Complex
4BYA 2014-06-18 Calmodulin, C-terminal domain, M144H mutant
1J7P 2001-11-07 Solution structure of Calcium calmodulin C-terminal domain
2K0F 2008-06-10 Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase
1CFD 1995-12-07 CALCIUM-FREE CALMODULIN
6GDK 2018-10-17 Calcium bound form of human calmodulin mutant F141L
2N77 2016-11-30 NMR solution structure of a complex of PEP-19 bound to the C-domain of apo calmodulin
1J7O 2001-11-07 Solution structure of Calcium-calmodulin N-terminal domain
1DMO 1996-08-01 CALMODULIN, NMR, 30 STRUCTURES
2O5G 2007-12-25 1.08 Calmodulin-smooth muscle light chain kinase peptide complex
4B1Y 2013-07-31 1.29 Structure of the Phactr1 RPEL-3 bound to G-actin
2PQ3 2007-10-16 1.3 N-Terminal Calmodulin Zn-Trapped Intermediate
2FXU 2006-03-07 1.35 X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution.
4DJC 2012-02-22 1.35 1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex
4K41 2014-10-01 1.4 Crystal structure of actin in complex with marine macrolide kabiramide C
3GOF 2010-03-31 1.45 Calmodulin bound to peptide from macrophage nitric oxide synthase
2Q0U 2007-07-17 1.45 Structure of Pectenotoxin-2 and Latrunculin B Bound to Actin
1WUA 2006-02-14 1.45 The structure of Aplyronine A-actin complex
2W73 2009-05-12 1.45 High-resolution structure of the complex between calmodulin and a peptide from calcineurin A
2F3Y 2005-12-27 1.45 Calmodulin/IQ domain complex
2V52 2008-11-25 1.45 Structure of MAL-RPEL2 complexed to G-actin
1QZ5 2003-11-11 1.45 Structure of rabbit actin in complex with kabiramide C
3GP2 2010-04-07 1.46 Calmodulin bound to peptide from calmodulin kinase II (CaMKII)
2PBD 2007-11-13 1.5 Ternary complex of profilin-actin with the poly-PRO-GAB domain of VASP*
4LZX 2014-05-07 1.5 Complex of IQCG and Ca2+-free CaM
3MN5 2010-06-02 1.5 Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
4J9Y 2013-03-27 1.51 Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant
5ZZA 2018-10-10 1.53 OdinProfilin/Rabbit Actin Complex
1J6Z 2001-08-15 1.54 UNCOMPLEXED ACTIN
2O60 2007-12-25 1.55 Calmodulin bound to peptide from neuronal nitric oxide synthase
5V03 2018-03-07 1.58 A positive allosteric modulator binding pocket in SK2 ion channels is shared by Riluzole and CyPPA
3CIP 2008-08-19 1.6 Complex of Dictyostelium Discoideum Actin with Gelsolin
3IF7 2010-06-30 1.6 Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine
1QZ6 2003-11-11 1.6 Structure of rabbit actin in complex with jaspisamide A
1S22 2004-02-17 1.6 Absolute Stereochemistry of Ulapualide A
2ASM 2005-10-11 1.6 Structure of Rabbit Actin In Complex With Reidispongiolide A
3B32 2007-11-13 1.6 Crystal Structure of Calcium-Saturated Calmodulin N-Terminal Domain Fragment, Residues 1-75
2F3Z 2005-12-27 1.6 Calmodulin/IQ-AA domain complex
1G4Y 2001-05-09 1.6 1.60 A CRYSTAL STRUCTURE OF THE GATING DOMAIN FROM SMALL CONDUCTANCE POTASSIUM CHANNEL COMPLEXED WITH CALCIUM-CALMODULIN
4G28 2012-09-12 1.63 Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and EBIO-1
2ASP 2005-10-11 1.64 Structure of Rabbit Actin In Complex With Reidispongiolide C
4G27 2012-09-12 1.65 Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea
6DAD 2018-10-17 1.65 1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex
4J9Z 2013-03-27 1.66 Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and NS309
6MBK 2018-12-19 1.69 SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, First P212121 Crystal Form
1FW4 2001-05-02 1.7 CRYSTAL STRUCTURE OF E. COLI FRAGMENT TR2C FROM CALMODULIN TO 1.7 A RESOLUTION
3SG6 2012-06-20 1.7 Crystal Structure of Dimeric GCaMP2-LIA(linker 1)
1CLL 1993-10-31 1.7 CALMODULIN STRUCTURE REFINED AT 1.7 ANGSTROMS RESOLUTION
1YR5 2006-07-04 1.7 1.7-A structure of calmodulin bound to a peptide from DAP kinase
2Q0R 2007-07-17 1.7 Structure of Pectenotoxin-2 Bound to Actin
1MXE 2002-12-04 1.7 Structure of the Complex of Calmodulin with the Target Sequence of CaMKI
3CI5 2008-08-19 1.7 Complex of Phosphorylated Dictyostelium Discoideum Actin with Gelsolin
5NIN 2017-12-06 1.7 Crystal Structure of AKAP79 calmodulin binding domain peptide in complex with Ca2+/Calmodulin
5DOW 2016-08-10 1.7 Solution of the Variably-Twinned Structure of a Novel Calmodulin-Peptide Complex in a Novel Configuration
2ASO 2005-10-11 1.7 Structure of Rabbit Actin In Complex With Sphinxolide B
1PRW 2003-10-10 1.7 Crystal structure of bovine brain Ca++ calmodulin in a compact form
5K8Q 2016-08-24 1.74 Crystal Structure of Calcium-loaded Calmodulin in complex with STRA6 CaMBP2-site peptide.
1D4X 2001-05-02 1.75 Crystal Structure of Caenorhabditis Elegans Mg-ATP Actin Complexed with Human Gelsolin Segment 1 at 1.75 A resolution.
4H03 2013-02-20 1.75 Crystal structure of NAD+-Ia-actin complex
3SJH 2012-01-25 1.75 Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP-Latrunculin A
3EVU 2008-12-09 1.75 Crystal structure of Calcium bound dimeric GCAMP2
4B1V 2012-11-07 1.75 Structure of the Phactr1 RPEL-N domain bound to G-actin
3UCW 2012-08-08 1.76 Structure of MG2+ bound N-Terminal domain of Calmodulin
6MBJ 2018-12-19 1.78 SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, P21 Crystal Form
5V02 2018-03-07 1.78 A positive allosteric modulator binding pocket in SK2 ion channels is shared by Riluzole and CyPPA
5JQA 2017-10-11 1.8 CaM:RM20 complex
1NM1 2003-01-21 1.8 Crystal Structure of D. Dicsoideum Actin Complexed With Gelsolin Segment 1 and Mg ATP at 1.8 A Resolution
6MBA 2019-04-10 1.8 Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin
3EKS 2008-10-07 1.8 Crystal Structure of Monomeric Actin bound to Cytochalasin D
4BW8 2014-01-15 1.8 Calmodulin with small bend in central helix
2A40 2005-11-01 1.8 Ternary complex of the WH2 domain of WAVE with Actin-DNAse I
1AHR 1997-06-16 1.8 CALMODULIN MUTANT WITH A TWO RESIDUE DELETION IN THE CENTRAL HELIX
4PKG 2014-07-30 1.8 Complex of ATP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
3UCY 2012-08-08 1.8 Structure of Mg2+ bound N-terminal domain of calmodulin in the presence of Zn2+
1IQ5 2001-09-26 1.8 Calmodulin/nematode CA2+/Calmodulin dependent kinase kinase fragment
2PAV 2007-10-23 1.8 Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP
4Q57 2014-07-23 1.8 Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex
1NLV 2003-01-21 1.8 Crystal Structure Of Dictyostelium Discoideum Actin Complexed With Ca ATP And Human Gelsolin Segment 1
2Y4V 2011-12-28 1.8 CRYSTAL STRUCTURE OF HUMAN CALMODULIN IN COMPLEX WITH A DAP KINASE-1 MUTANT (W305Y) PEPTIDE
2HF4 2006-08-29 1.8 Crystal structure of Monomeric Actin in its ATP-bound state
3W3D 2013-01-30 1.8 Crystal structure of smooth muscle G actin DNase I complex
2HF3 2006-08-29 1.8 Crystal structure of monomeric Actin in the ADP bound state
4B1X 2013-07-31 1.8 Structure of the Phactr1 RPEL-2 bound to G-actin
4BW7 2014-01-15 1.81 Calmodulin in complex with strontium
5YEE 2018-09-19 1.81 Crystal structure of LokiProfilin1/Rabbit Actin Complex
5JTH 2017-07-19 1.84 Crystal structure of E67A calmodulin - CaM:RM20 complex
3BYA 2009-01-20 1.85 Structure of a Calmodulin Complex
2A42 2005-11-01 1.85 Actin-DNAse I Complex
1NWK 2003-10-14 1.85 CRYSTAL STRUCTURE OF MONOMERIC ACTIN IN THE ATP STATE
3EK7 2008-12-16 1.85 Calcium-saturated GCaMP2 dimer
2R28 2008-07-01 1.86 The complex Structure of Calmodulin Bound to a Calcineurin Peptide
6O5G 2019-08-07 1.89 Calmodulin in complex with isomalbrancheamide D
1UP5 2005-03-24 1.9 Chicken Calmodulin
4EHQ 2012-11-07 1.9 Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode
3UCT 2012-08-08 1.9 Structure of Mn2+-bound N-terminal domain of calmodulin in the presence of Zn2+
2HQW 2007-11-13 1.9 Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide
2HMP 2006-09-19 1.9 Uncomplexed actin cleaved with protease ECP32
1NMD 2003-02-04 1.9 Crystal Structure of D. Discoideum Actin-Gelsolin Segment 1 Complex Crystallized In Presence Of Lithium ATP
3SJQ 2012-05-30 1.9 Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin
3SG5 2012-06-20 1.9 Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2)
2WEL 2009-04-14 1.9 Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin
6MUE 2019-05-08 1.9 Voltage-gated sodium channel NaV1.4 IQ domain in complex with Ca2+/Calmodulin
2GWJ 2006-08-29 1.9 SpvB ADP-ribosylated actin: hexagonal crystal form
5WBX 2017-12-20 1.9 Structural insights into the potency of SK/IK channel positive modulators
3SG7 2012-06-20 1.9 Crystal Structure of GCaMP3-KF(linker 1)
1ZUZ 2006-11-14 1.91 Calmodulin in complex with a mutant peptide from human DRP-1 kinase
5DSU 2017-01-11 1.93 Crystal structure of double mutant of N-domain of human calmodulin
2VAY 2008-09-16 1.94 Calmodulin complexed with CaV1.1 IQ peptide
4H0Y 2013-02-20 1.94 Crystal structure of NAD+-Ia(E380S)-actin complex
4Q5U 2014-09-03 1.95 Structure of calmodulin bound to its recognition site from calcineurin
3SUI 2012-09-12 1.95 Crystal structure of ca2+-calmodulin in complex with a trpv1 c-terminal peptide
3WFN 2013-08-28 1.95 Crystal Structure of Nav1.6 IQ motif in complex with apo-CaM
4B1W 2013-07-31 1.95 Structure of the Phactr1 RPEL-2 domain bound to actin
6ICT 2019-02-27 1.95 Structure of SETD3 bound to SAH and methylated actin
6EEB 2019-08-07 1.96 Calmodulin in complex with malbrancheamide
5NOJ 2017-08-02 11.0 Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - 'OPEN' state
6CXI 2018-10-10 11.0 Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 1
5NOG 2017-07-19 11.0 Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - 'Blocked' state
6CXJ 2018-10-10 11.0 Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 2
3BYH 2008-02-19 12.0 Model of actin-fimbrin ABD2 complex
3J8J 2015-01-14 12.0 Tilted state of actin, T1
3J8K 2015-01-14 12.0 Tilted state of actin, T2
3LUE 2010-04-28 15.0 Model of alpha-actinin CH1 bound to F-actin
1LIN 1996-03-08 2.0 CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:4 COMPLEX)
3EKH 2008-12-16 2.0 Calcium-saturated GCaMP2 T116V/K378W mutant monomer
3SG2 2012-06-20 2.0 Crystal Structure of GCaMP2-T116V,D381Y
6HCS 2018-12-05 2.0 Crystal structure of CaM-peptide complex containing AzF at position 108
5J03 2016-09-07 2.0 Crystal Structure of a chimeric Kv7.2 - Kv7.3 proximal C-terminal Domain in Complex with Calmodulin
1ESV 2000-07-19 2.0 COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1
4HEX 2013-03-06 2.0 A novel conformation of calmodulin
1WRZ 2006-03-21 2.0 Calmodulin complexed with a peptide from a human death-associated protein kinase
2GWK 2006-08-29 2.0 SpvB ADP-ribosylated actin: orthorhombic crystal form
1CM1 1998-03-04 2.0 MOTIONS OF CALMODULIN-SINGLE-CONFORMER REFINEMENT
2I08 2007-08-21 2.0 Solvation effect in conformational changes of EF-hand proteins: X-ray structure of Ca2+-saturated double mutant Q41L-K75I of N-domain of calmodulin
1CDL 1994-08-31 2.0 TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX
3DNI 1994-01-31 2.0 CRYSTALLOGRAPHIC REFINEMENT AND STRUCTURE OF DNASE I AT 2 ANGSTROMS RESOLUTION
3M6G 2010-09-08 2.0 Crystal structure of actin in complex with lobophorolide
4RJD 2015-08-26 2.0 TFP bound in alternate orientations to calcium-saturated Calmodulin C-Domains
4PL8 2014-10-22 2.0 Structure of rabbit skeletal muscle actin in complex with a hybrid peptide comprising thymosin beta4 and the lysine-rich region of Cordon-Bleu
1CM4 1998-03-04 2.0 Motions of calmodulin-four-conformer refinement
1IWQ 2003-03-11 2.0 Crystal Structure of MARCKS calmodulin binding domain peptide complexed with Ca2+/Calmodulin
4B1U 2013-07-31 2.0 Structure of the Phactr1 RPEL domain and RPEL motif directed assemblies with G-actin reveal the molecular basis for actin binding cooperativity.
5YPU 2018-09-26 2.0 Crystal structure of an actin monomer in complex with the nucleator Cordon-Bleu MET72NLE WH2-motif peptide
3MN9 2010-05-26 2.0 Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
2BCX 2006-10-31 2.0 Crystal structure of calmodulin in complex with a ryanodine receptor peptide
2FF3 2006-03-21 2.0 Crystal structure of Gelsolin domain 1:N-wasp V2 motif hybrid in complex with actin
1T44 2004-09-07 2.0 Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation
3MN7 2010-05-26 2.0 Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
3MN6 2010-06-02 2.0 Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
2BE6 2005-11-15 2.0 2.0 A crystal structure of the CaV1.2 IQ domain-Ca/CaM complex
2DNJ 1994-01-31 2.0 DNASE I-INDUCED DNA CONFORMATION. 2 ANGSTROMS STRUCTURE OF A DNASE I-OCTAMER COMPLEX
3U8X 2012-01-25 2.0 Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP
1CDM 1994-08-31 2.0 MODULATION OF CALMODULIN PLASTICITY IN MOLECULAR RECOGNITION ON THE BASIS OF X-RAY STRUCTURES
3EVR 2008-12-09 2.0 Crystal structure of Calcium bound monomeric GCAMP2
6DAE 2018-10-17 2.0 2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex
1C0G 2000-03-01 2.0 CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 228: Q228K/T229A/A230Y/E360H)
1YXQ 2005-05-17 2.01 Crystal structure of actin in complex with swinholide A
4QNH 2014-08-06 2.02 Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a
4OY4 2015-02-18 2.03 calcium-free CaMPARI v0.2
3IFK 2009-12-15 2.03 Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90
4H0V 2013-02-20 2.03 Crystal structure of NAD+-Ia(E378S)-actin complex
1NIW 2003-02-18 2.05 Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin
2FF6 2006-03-21 2.05 Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin
2A3Z 2005-11-01 2.08 Ternary complex of the WH2 domain of WASP with Actin-DNAse I
3U9Z 2012-01-25 2.09 Crystal structure between actin and a protein construct containing the first beta-thymosin domain of drosophila ciboulot (residues 2-58) with the three mutations N26D/Q27K/D28S
3G43 2009-03-03 2.1 Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer
4M1L 2014-05-07 2.1 Complex of IQCG and Ca2+-bound CaM
3SG3 2012-06-20 2.1 Crystal Structure of GCaMP3-D380Y
1YRT 2006-01-17 2.1 Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin
1KXP 2002-06-19 2.1 CRYSTAL STRUCTURE OF HUMAN VITAMIN D-BINDING PROTEIN IN COMPLEX WITH SKELETAL ACTIN
1OOJ 2003-03-25 2.11 Structural genomics of Caenorhabditis elegans : Calmodulin
1XA5 2004-12-21 2.12 Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid
2V01 2007-08-14 2.15 Recombinant vertebrate calmodulin complexed with Pb
6ICV 2019-02-27 2.15 Structure of SETD3 bound to SAH and unmodified actin
6N5W 2019-03-13 2.15 Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains
4PKH 2014-07-30 2.15 Complex of ADP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
2F2O 2006-02-21 2.17 Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode
4I2Y 2013-07-24 2.2 Crystal Structure of the genetically encoded calcium indicator RGECO1
4DBP 2013-01-30 2.2 Myosin VI nucleotide-free (MDINSERT2) D179Y crystal structure
6MGO 2018-11-21 2.2 Structure of rabbit actin in complex with Mycalolide B
6B8N 2018-03-14 2.2 Crystal Structure of the Ca2+/CaM:Kv7.4 (KCNQ4) AB Domain Complex, 10 uM CaCl2 soak
4CLN 1992-07-15 2.2 STRUCTURE OF A RECOMBINANT CALMODULIN FROM DROSOPHILA MELANOGASTER REFINED AT 2.2-ANGSTROMS RESOLUTION
3UB5 2012-04-25 2.2 Profilin:actin with a wide open nucleotide cleft
6CZQ 2018-08-01 2.2 A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
2X51 2011-01-26 2.2 M6 delta Insert1
6B8P 2018-03-14 2.2 Crystal Structure of the Mg2+/CaM:Kv7.4 (KCNQ4) AB domain complex
1ZOT 2005-08-09 2.2 crystal structure analysis of the CyaA/C-Cam with PMEAPP
4DCK 2012-06-27 2.2 Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM
2V02 2007-08-14 2.2 Recombinant vertebrate calmodulin complexed with Ba
6MBL 2018-12-19 2.2 SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, Second P212121 Crystal Form
4H0T 2013-02-20 2.2 Crystal structure of Ia-ADPR-actin complex
3CLN 1988-07-16 2.2 STRUCTURE OF CALMODULIN REFINED AT 2.2 ANGSTROMS RESOLUTION
1MDU 2003-01-07 2.2 Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)
2X0G 2010-01-26 2.2 X-RAY STRUCTURE OF A DAP-KINASE CALMODULIN COMPLEX
2COL 2006-01-24 2.2 Crystal structure analysis of CyaA/C-Cam with Pyrophosphate
3L9I 2010-12-08 2.2 Myosin VI nucleotide-free (mdinsert2) L310G mutant crystal structure
3D2U 2008-07-08 2.21 Structure of UL18, a Peptide-Binding Viral MHC Mimic, Bound to a Host Inhibitory Receptor
2YGG 2011-09-28 2.23 Complex of CaMBR and CaM
5DBR 2017-02-22 2.25 Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate
3CHW 2008-08-19 2.3 Complex of Dictyostelium discoideum Actin with Profilin and the Last Poly-Pro of Human VASP
6B8L 2018-03-14 2.3 Crystal Structure of the Apo/CaM:Kv7.4 (KCNQ4) AB Domain Complex
6B8M 2018-03-14 2.3 Crystal Structure of the Ca2+/CaM:Kv7.4 (KCNQ4) AB Domain Complex, 1 mM CaCl2 soak
1QIW 2000-03-28 2.3 Calmodulin complexed with N-(3,3,-diphenylpropyl)-N'-[1-R-(3,4-bis-butoxyphenyl)-ethyl]-propylenediamine (DPD)
5ZZB 2018-10-10 2.3 LokiProfilin2/Rabbit Actin Complex
1EQY 2000-05-03 2.3 COMPLEX BETWEEN RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1
3BXL 2008-03-25 2.3 Crystal structure of the R-type calcium channeL (CaV2.3) IQ domain and CA2+calmodulin complex
1RDW 2003-12-16 2.3 Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer
3DVK 2008-11-04 2.3 Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex
1DNK 1994-01-31 2.3 THE X-RAY STRUCTURE OF THE DNASE I-D(GGTATACC)2 COMPLEX AT 2.3 ANGSTROMS RESOLUTION
4L79 2014-01-29 2.3 Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin
4PKI 2014-07-30 2.3 Complex of ATP-actin With the C-terminal Actin-Binding Domain of Tropomodulin
2VB6 2007-12-11 2.3 Myosin VI (MD-insert2-CaM, Delta Insert1) Post-rigor state (crystal form 2)
5WC5 2017-12-20 2.3 Structural insights into the potency of SK/IK channel positive modulators
1L7Z 2003-09-16 2.3 Crystal structure of Ca2+/Calmodulin complexed with myristoylated CAP-23/NAP-22 peptide
4H0X 2013-02-20 2.33 Crystal structure of NAD+-Ia(E380A)-actin complex
5WSV 2017-06-07 2.33 Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM
4UPU 2014-08-20 2.34 Crystal structure of IP3 3-K calmodulin binding region in complex with Calmodulin
2VYP 2009-02-24 2.35 Rabbit-muscle G-actin in complex with myxobacterial rhizopodin
3O77 2010-09-29 2.35 The structure of Ca2+ Sensor (Case-16)
2V51 2008-11-25 2.35 Structure of MAL-RPEL1 complexed to actin
3DVE 2008-11-04 2.35 Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain complex
3A5N 2010-10-27 2.36 Crystal Structure of a Dictyostelium P109A Ca2+-Actin in Complex with Human Gelsolin Segment 1
5UBO 2017-12-20 2.39 Mical-oxidized Actin complex with Gelsolin Segment 1
3A5L 2010-10-27 2.4 Crystal Structure of a Dictyostelium P109A Mg2+-Actin in Complex with Human Gelsolin Segment 1
1Y6W 2005-03-01 2.4 Trapped intermediate of calmodulin
1DEJ 2000-03-01 2.4 CRYSTAL STRUCTURE OF A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 646: Q228K/T229A/A230Y/A231K/S232E/E360H) IN COMPLEX WITH HUMAN GELSOLIN SEGMENT 1
3U4L 2012-04-25 2.4 Cryocooled bovine profilin:actin crystal structure to 2.4 A
6QRI 2019-07-03 2.4 Structure of rabbit G-actin in complex with chivosazole A
2VAS 2007-12-11 2.4 Myosin VI (MD-insert2-CaM, Delta-Insert1) Post-rigor state
3A5O 2010-10-27 2.4 Crystal Structure of a Dictyostelium P109I Ca2+-Actin in Complex with Human Gelsolin Segment 1
4Z94 2015-10-21 2.4 Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2
3EWT 2009-10-20 2.4 Crystal Structure of calmodulin complexed with a peptide
1C0F 2000-03-01 2.4 CRYSTAL STRUCTURE OF DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1
2BKH 2005-06-07 2.4 Myosin VI nucleotide-free (MDInsert2) crystal structure
3A5M 2010-10-27 2.4 Crystal Structure of a Dictyostelium P109I Mg2+-Actin in Complex with Human Gelsolin Segment 1
3SG4 2012-06-20 2.4 Crystal Structure of GCaMP3-D380Y, LP(linker 2)
6DAF 2018-10-17 2.4 2.4 Angstrom crystal structure of the F141L Ca/CaM:CaV1.2 IQ domain complex
1MA9 2003-02-04 2.4 Crystal structure of the complex of human vitamin D binding protein and rabbit muscle actin
4PJJ 2015-04-29 2.4 MYOSIN VI (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state - long soaking with PO4
2FOT 2006-09-05 2.45 Crystal structure of the complex between calmodulin and alphaII-spectrin
1CTR 1994-12-20 2.45 DRUG BINDING BY CALMODULIN: CRYSTAL STRUCTURE OF A CALMODULIN-TRIFLUOPERAZINE COMPLEX
4EFH 2012-04-11 2.48 Acanthamoeba Actin complex with Spir domain D
2A5X 2005-08-23 2.49 Crystal Structure of a Cross-linked Actin Dimer
3WLC 2014-01-22 2.49 Crystal structure of dimeric GCaMP6m
1SQK 2004-06-15 2.5 CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN
1LOT 2002-07-31 2.5 CRYSTAL STRUCTURE OF THE COMPLEX OF ACTIN WITH VITAMIN D-BINDING PROTEIN
1YRU 2005-09-27 2.5 Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin and 1mM calcium chloride
4ZLK 2016-05-04 2.5 Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin
2Q97 2007-10-16 2.5 Complex of mammalian actin with toxofilin from toxoplasma gondii
2D1K 2006-09-12 2.5 Ternary complex of the WH2 domain of mim with actin-dnase I
3HR4 2009-09-08 2.5 Human iNOS Reductase and Calmodulin Complex
6ALE 2018-08-08 2.5 A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
6DAH 2018-10-17 2.5 2.5 Angstrom crystal structure of the N97S CaM mutant
2Q36 2007-06-05 2.5 Actin Dimer Cross-linked between Residues 191 and 374 and complexed with Kabiramide C
2IX7 2006-12-13 2.5 Structure of apo-calmodulin bound to unconventional myosin V
3U9D 2012-01-25 2.5 Crystal Structure of a chimera containing the N-terminal domain (residues 8-24) of drosophila Ciboulot and the C-terminal domain (residues 13-44) of bovine Thymosin-beta4, bound to G-actin-ATP
3EL2 2008-10-07 2.5 Crystal Structure of Monomeric Actin Bound to Ca-ATP
3EKU 2008-10-07 2.5 Crystal Structure of Monomeric Actin bound to Cytochalasin D
1QX5 2004-08-31 2.54 Crystal structure of apoCalmodulin
3BXK 2008-03-25 2.55 Crystal structure of the P/Q-type calcium channel (CaV2.1) IQ domain and CA2+calmodulin complex
3OXQ 2010-11-03 2.55 Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex
3DAW 2008-07-29 2.55 Structure of the actin-depolymerizing factor homology domain in complex with actin
2BTF 1994-06-22 2.55 THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN
5H7D 2017-06-28 2.57 Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex
4DBQ 2013-01-30 2.6 MYOSIN VI D179Y (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state
1P8Z 2003-10-14 2.6 Complex Between Rabbit Muscle alpha-Actin: Human Gelsolin Residues Val26-Glu156
4GOW 2012-12-12 2.6 Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex
3O78 2010-09-29 2.6 The structure of Ca2+ Sensor (Case-12)
4ANJ 2012-10-17 2.6 MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4)
3EVV 2008-12-09 2.6 Crystal Structure of Calcium bound dimeric GCAMP2 (#2)
2F2P 2006-02-21 2.6 Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode
2A41 2005-11-01 2.6 Ternary complex of the WH2 Domain of WIP with Actin-DNAse I
6GVC 2019-03-27 2.6 Structure of ArhGAP12 bound to G-Actin
3EWV 2009-10-20 2.6 Crystal Structure of calmodulin complexed with a peptide
3DVM 2008-11-04 2.6 Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex
3KF9 2011-01-26 2.6 Crystal structure of the SdCen/skMLCK complex
6B8Q 2018-03-14 2.6 Crystal Structure of the Mg2+/CaM:Kv7.5 (KCNQ5) AB domain complex
2OAN 2007-05-01 2.61 Structure of oxidized beta-actin
1QIV 2000-03-28 2.64 CALMODULIN COMPLEXED WITH N-(3,3,-DIPHENYLPROPYL)-N'-[1-R-(3,4-BIS-BUTOXYPHENYL)-ETHYL]-PROPYLENEDIAMINE (DPD), 1:2 COMPLEX
3EK4 2008-12-16 2.65 Calcium-saturated GCaMP2 Monomer
1HLU 1997-10-15 2.65 STRUCTURE OF BOVINE BETA-ACTIN-PROFILIN COMPLEX WITH ACTIN BOUND ATP PHOSPHATES SOLVENT ACCESSIBLE
5COC 2016-03-30 2.67 Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus
4E53 2013-03-20 2.69 Calmodulin and Nm peptide complex
6MUD 2019-05-08 2.69 Voltage-gated sodium channel NaV1.5 C-terminal domain in complex with Ca2+/Calmodulin
3WLD 2014-01-22 2.7 Crystal structure of monomeric GCaMP6m
3HBT 2010-05-05 2.7 The structure of native G-actin
2Q1N 2007-06-05 2.7 Actin Dimer Cross-linked Between Residues 41 and 374
4E50 2013-03-20 2.7 Calmodulin and Ng peptide complex
2Q31 2007-06-05 2.7 Actin Dimer Cross-linked Between Residues 41 and 374 and proteolytically cleaved by subtilisin between residues 47 and 48.
3GN4 2009-09-08 2.7 Myosin lever arm
4GY2 2013-02-20 2.71 Crystal structure of apo-Ia-actin complex
6K4K 2019-07-24 2.71 Crystal structure of SidJ-CaM binary complex at 2.71 A
1A29 1998-09-16 2.74 CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:2 COMPLEX)
4BYF 2014-03-26 2.74 Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state
1K90 2002-01-23 2.75 Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
4M63 2013-10-23 2.75 Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
3UE5 2012-02-15 2.76 ECP-cleaved Actin in complex with Spir domain D
3DVJ 2008-11-04 2.8 Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex
6FM2 2018-05-16 2.8 CARP domain of mouse cyclase-associated protein 1 (CAP1) bound to ADP-actin
4OVN 2014-12-03 2.8 Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation
3EK8 2008-12-16 2.8 Calcium-saturated GCaMP2 T116V/G87R mutant monomer
3MMV 2010-06-02 2.8 Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
3EKJ 2008-12-16 2.8 Calcium-free GCaMP2 (calcium binding deficient mutant)
1ATN 1992-07-15 2.8 Atomic structure of the actin:DNASE I complex
3BUZ 2008-05-13 2.81 Crystal structure of ia-bTAD-actin complex
1IJJ 2002-04-15 2.85 THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION
5HIT 2016-09-14 2.85 Crystal Structure Analysis of Ca2+-calmodulin and a C-terminal EAG1 channel fragment
4V0C 2014-11-05 2.86 Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin
3M1F 2010-09-15 2.89 Crosslinked complex of actin with first W domain of Vibrio parahaemolyticus VopL
2BKI 2005-06-07 2.9 Myosin VI nucleotide-free (MDinsert2-IQ) crystal structure
4K43 2014-10-01 2.9 Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]
1DEG 1994-05-31 2.9 THE LINKER OF DES-GLU84 CALMODULIN IS BENT AS SEEN IN THE CRYSTAL STRUCTURE
4K42 2014-10-01 2.9 Crystal structure of actin in complex with synthetic AplC tail analogue SF01 [(3R,4S,5R,6S,10R,11R,12R)-11-(acetyloxy)-1-(benzyloxy)-14-[formyl(methyl)amino]-5-hydroxy-4,6,10,12-tetramethyl-9-oxotetradecan-3-yl propanoate]
4JHD 2013-06-19 2.91 Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu
6K4L 2019-07-24 2.95 Crystal structure of Se-labelled SidJ complex with CaM at 2.95 A
1K93 2002-01-23 2.95 Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin
4RWT 2015-10-14 2.98 Structure of actin-Lmod complex
1H1V 2003-01-24 2.99 gelsolin G4-G6/actin complex
2Y83 2011-03-30 22.9 Actin filament pointed end
3J41 2013-07-31 25.0 Pseudo-atomic model of the Aquaporin-0/Calmodulin complex derived from electron microscopy
5MVA 2017-11-29 27.7 Structure of the thin filament at high calcium concentration
5MVY 2018-02-14 28.4 Thin Filament at low calcium concentration
4UMO 2014-11-05 3.0 Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin
1S26 2004-04-13 3.0 Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site
4IL1 2013-10-02 3.0 Crystal Structure of the Rat Calcineurin
3FFK 2009-10-06 3.0 Crystal structure of human Gelsolin domains G1-G3 bound to Actin
1RGI 2004-07-27 3.0 Crystal structure of gelsolin domains G1-G3 bound to actin
5WFN 2017-08-30 3.0 Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT)
5WSU 2017-06-07 3.0 Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM
3TU5 2012-09-26 3.0 Actin complex with Gelsolin Segment 1 fused to Cobl segment
1RFQ 2003-12-16 3.0 Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer
4JPZ 2014-04-16 3.02 Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin
1Y64 2005-01-18 3.05 Bni1p Formin Homology 2 Domain complexed with ATP-actin
1QX7 2004-08-31 3.09 Crystal structure of apoCaM bound to the gating domain of small conductance Ca2+-activated potassium channel
6DJN 2019-02-27 3.1 Cryo-EM structure of ADP-Pi-actin filaments
2YJE 2011-07-06 3.1 Oligomeric assembly of actin bound to MRTF-A
6DJM 2019-02-27 3.1 Cryo-EM structure of AMPPNP-actin filaments
6K4R 2019-07-24 3.11 Crystal structure of SidJ-CaM-AMP ternary complex at 3.11 A
5V7X 2018-02-28 3.14 Crystal Structure of Myosin 1b residues 1-728 with bound sulfate and Calmodulin
5I0I 2016-09-07 3.15 Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state
2VCP 2008-11-04 3.2 Crystal structure of N-Wasp VC domain in complex with skeletal actin
1SK6 2004-06-08 3.2 Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate
6C1D 2018-01-31 3.2 High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
1XFX 2005-05-03 3.2 Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride
3CJB 2008-03-25 3.21 Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1
1XFZ 2005-05-03 3.25 Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride
2ZWH 2009-01-20 3.3 Model for the F-actin structure
6FHL 2018-06-13 3.3 Cryo-EM structure of F-actin in complex with ADP-Pi
4B1Z 2012-11-07 3.3 Structure of the Phactr1 RPEL domain bound to G-actin
1PK0 2004-02-10 3.3 Crystal Structure of the EF3-CaM complexed with PMEApp
6MC9 2019-04-10 3.3 Crystal Structure of Human Nav1.4 C-Terminal (1599-1754) domain in complex with calcium-bound calmodulin
1XFY 2005-05-03 3.3 Crystal structure of anthrax edema factor (EF) in complex with calmodulin
6O20 2019-04-24 3.3 Cryo-EM structure of TRPV5 with calmodulin bound
1XFU 2005-05-03 3.35 Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin
1XFV 2005-05-03 3.35 Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
6CNM 2018-05-02 3.4 Cryo-EM structure of the human SK4/calmodulin channel complex
4EAH 2012-12-12 3.4 Crystal structure of the formin homology 2 domain of FMNL3 bound to actin
1XFW 2005-05-03 3.4 Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP)
5OOF 2018-06-13 3.4 Cryo-EM structure of F-actin in complex with ADP-BeFx
3TPQ 2011-10-12 3.45 Crystal structure of wild-type MAL RPEL domain in complex with five G-actins
4WYB 2015-08-19 3.49 Structure of the Bud6 flank domain in complex with actin
6F1T 2018-01-17 3.5 Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1
2YJF 2011-07-06 3.5 Oligomeric assembly of actin bound to MRTF-A
1LCU 2002-05-01 3.5 Polylysine Induces an Antiparallel Actin Dimer that Nucleates Filament Assembly: Crystal Structure at 3.5 A Resolution
6CNN 2018-05-02 3.5 Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state I
4R8G 2014-12-03 3.5 Crystal Structure of Myosin-1c tail in complex with Calmodulin
6D8C 2018-09-19 3.54 Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin
5JLF 2016-06-15 3.6 Structure of the F-actin-tropomyosin complex (reprocessed)
6E2G 2018-08-22 3.6 Cryo-EM structure of rat TRPV6 in complex with Calmodulin
5OOC 2018-06-13 3.6 Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP
1Y0V 2005-05-03 3.6 Crystal structure of anthrax edema factor (EF) in complex with calmodulin and pyrophosphate
6DJO 2019-02-27 3.6 Cryo-EM structure of ADP-actin filaments
5OOE 2018-06-13 3.6 Cryo-EM structure of F-actin in complex with AppNHp (AMPPNP)
1LVC 2002-12-04 3.6 Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP
5OOD 2018-06-13 3.7 Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP-Pi
3J8A 2014-12-10 3.7 Structure of the F-actin-tropomyosin complex
5VMS 2017-06-07 3.7 CryoEM structure of Xenopus KCNQ1 channel
5K7L 2016-08-17 3.78 Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
6C1G 2018-01-31 3.8 High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
5YU8 2018-05-23 3.8 Cofilin decorated actin filament
4JQ0 2014-05-21 3.84 Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin
6C1H 2018-01-31 3.9 High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
6AVB 2018-01-17 3.9 CryoEM structure of Mical Oxidized Actin (Class 1)
3CJC 2008-03-25 3.9 Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with DNase I and Gelsolin-segment 1
6E2F 2018-08-22 3.9 Cryo-EM structure of human TRPV6 in complex with Calmodulin
6AV9 2018-01-17 3.9 CryoEM structure of Mical Oxidized Actin (Class 1)
5JLH 2016-06-15 3.9 Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
5ADX 2015-12-30 4.0 CryoEM structure of dynactin complex at 4.0 angstrom resolution
5ONV 2018-06-13 4.1 Cryo-EM structure of F-actin in complex with ADP
6S5T 2019-07-24 4.15 Legionella pneumophila SidJ-Human calmodulin complex
6DMW 2018-10-24 4.4 Calmodulin-bound full-length rbTRPV5
6BNV 2018-01-10 4.6 CryoEM structure of MyosinVI-actin complex in the rigor (nucleotide-free) state, backbone-averaged with side chains truncated to alanine
6BNP 2018-01-10 4.6 CryoEM structure of MyosinVI-actin complex in the rigor (nucleotide-free) state
3J8I 2015-01-14 4.7 Near-Atomic Resolution for One State of F-Actin
6CNO 2018-05-02 4.7 Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state II
5H53 2017-01-18 5.2 The structure of rabbit skeletal muscle actomyosin rigor complex at 5.2 angstrom.
6BNQ 2018-01-10 5.5 CryoEM structure of Myosin VI-Actin complex in the ADP state
6BNW 2018-01-10 5.5 CryoEM structure of Myosin VI-Actin complex in the ADP state, backbone-averaged with side chains truncated to alanine
6BNO 2018-01-10 5.5 Structure of bare actin filament
6BIH 2018-09-19 6.0 The Structure of the Actin-Smooth Muscle Myosin Motor Domain Complex in the Rigor State
3G37 2010-11-03 6.0 Cryo-EM structure of actin filament in the presence of phosphate
3MFP 2010-09-29 6.6 Atomic model of F-actin based on a 6.6 angstrom resolution cryoEM map
6F38 2018-01-17 6.7 Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3
6ANU 2017-11-22 7.0 Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain
3M3N 2010-07-28 7.0 Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains
6BNU 2018-01-10 7.5 Structure of bare actin filament, backbone-averaged with sidechains truncated to alanine
3JBJ 2015-11-04 7.6 Cryo-EM reconstruction of F-actin
4A7F 2012-08-01 7.7 Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3)
3J82 2015-05-20 7.7 Electron cryo-microscopy of DNGR-1 in complex with F-actin
4A7H 2012-08-01 7.8 Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)
4V0U 2015-03-25 7.88 The crystal structure of ternary PP1G-PPP1R15B and G-actin complex
1O1A 2002-12-04 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1MVW 2002-11-20 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O1F 2002-12-04 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O18 2002-11-27 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O1E 2002-12-04 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O1G 2002-12-11 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O1C 2002-12-04 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O19 2002-11-27 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1O1D 2002-12-04 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
1M8Q 2002-09-10 70.0 Molecular Models of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
1O1B 2002-12-04 70.0 MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
3J4K 2013-09-25 8.0 Cryo-EM structures of the actin:tropomyosin filament reveal the mechanism for the transition from C- to M-state
5NOL 2017-07-19 8.0 Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - 'Closed' state
4A7L 2012-08-01 8.1 Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1)
3JBK 2015-11-04 8.2 Cryo-EM reconstruction of the metavinculin-actin interface
5AFU 2015-03-11 8.2 Cryo-EM structure of dynein tail-dynactin-BICD2N complex
6F3A 2018-01-17 8.2 Cryo-EM structure of a single dynein tail domain bound to dynactin and BICD2N
3JBI 2015-11-04 8.5 MDFF model of the vinculin tail domain bound to F-actin
4A7N 2012-08-01 8.9 Structure of bare F-actin filaments obtained from the same sample as the Actin-Tropomyosin-Myosin Complex
6G2T 2018-10-17 9.0 human cardiac myosin binding protein C C1 Ig-domain bound to native cardiac thin filament
3J0S 2011-12-21 9.0 Remodeling of actin filaments by ADF cofilin proteins
5KG8 2016-09-07 9.1 Rigor myosin X co-complexed with an actin filament
3B63 2008-11-18 9.5 Actin filament model in the extended form of acromsomal bundle in the Limulus sperm

Relevant UniProtKB Entries

Percent Identity Matching Chains Protein Accession Entry Name
100.0 B Calmodulin P20689 MYLK2_RAT
100.0 B Calmodulin P07313 MYLK2_RABIT
100.0 B Calmodulin Q8VCR8 MYLK2_MOUSE
100.0 B Calmodulin Q9H1R3 MYLK2_HUMAN
100.0 B Calmodulin A4IFM7 MYLK2_BOVIN
93.5 A Calmodulin P18061 CALM_TRYCR
93.5 A Calmodulin P69098 CALM_TRYBG
93.5 A Calmodulin P69097 CALM_TRYBB
100.0 A Calmodulin P62184 CALM_RENRE
100.0 A Calmodulin P11121 CALM_PYUSP
100.0 A Calmodulin P02595 CALM_PATSP
92.3 A Calmodulin P53440 CALMF_NAEGR
94.2 A Calmodulin P11118 CALM_EUGGR
100.0 A Calmodulin P02594 CALM_ELEEL
91.4 A Calmodulin P05932 CALMB_ARBPU
96.5 A Calmodulin Q9HFY6 CALM_BLAEM
100.0 A Calmodulin Q40302 CALM_MACPY
91.9 A Calmodulin P62150 CALM_ORYLA
95.7 A Calmodulin O02367 CALM_CIOIN
91.2 A Calmodulin P27166 CALM_STYLE
91.2 A Calmodulin O97341 CALM_SUBDO
91.2 A Calmodulin A8I1Q0 CALM_HETTR
92.6 A Calmodulin P02598 CALM_TETPY
92.6 A Calmodulin A3E4D8 CALM_PROMN
92.6 A Calmodulin A3E3H0 CALM_PFIPI
92.6 A Calmodulin A3E4F9 CALM_KARVE
92.6 A Calmodulin A4UHC0 CALM_ALEFU
92.6 A Calmodulin O96081 CALMB_HALRO
92.6 A Calmodulin P62146 CALMA_ARBPU
98.3 A Calmodulin Q95NR9 CALM_METSE
97.4 A Calmodulin Q7T3T2 CALM_EPIAK
98.3 A Calmodulin P0DP35 CAM2B_XENLA
98.3 A Calmodulin P0DP34 CAM2A_XENLA
98.3 A Calmodulin P62151 CALM_TETCF
98.3 A Calmodulin P21251 CALM_STIJA
98.3 A Calmodulin Q6YNX6 CALM_SHEEP
98.3 A Calmodulin P62160 CALM_RABIT
98.3 A Calmodulin Q5RAD2 CALM_PONAB
98.3 A Calmodulin Q71UH6 CALM_PERFV
98.3 A Calmodulin P62156 CALM_ONCSP
98.3 A Calmodulin Q6PI52 CALM_DANRE
98.3 A Calmodulin Q6IT78 CALM_CTEID
98.3 A Calmodulin P62149 CALM_CHICK
98.3 A Calmodulin P62157 CALM_BOVIN
98.3 A Calmodulin P62144 CALM_ANAPL
98.3 A Calmodulin P0DP31 CALM3_RAT
98.3 A Calmodulin P0DP28 CALM3_MOUSE
98.3 A Calmodulin P0DP25 CALM3_HUMAN
98.3 A Calmodulin P0DP30 CALM2_RAT
98.3 A Calmodulin P0DP27 CALM2_MOUSE
98.3 A Calmodulin P0DP24 CALM2_HUMAN
99.1 A Calmodulin Q9UB37 CALM2_BRALA
98.3 A Calmodulin P0DP33 CALM1_XENLA
98.3 A Calmodulin P0DP29 CALM1_RAT
98.3 A Calmodulin P0DP26 CALM1_MOUSE
98.3 A Calmodulin P0DP23 CALM1_HUMAN
98.0 A Calmodulin Q8STF0 CALM_STRIE
99.3 A Calmodulin P62154 CALM_LOCMI
99.3 A Calmodulin P62152 CALM_DROME
99.3 A Calmodulin P62145 CALM_APLCA
99.3 A Calmodulin P62153 CALMA_HALRO
99.3 A Calmodulin P62148 CALM1_BRALA
99.3 A Calmodulin P62147 CALM1_BRAFL
98.6 A Calmodulin O16305 CALM_CAEEL
93.8 Actin, alpha skeletal muscle Q24733 ACT_DICVI
93.3 Actin, alpha skeletal muscle P85911 ACT1_PSEMZ
96.5 Actin, alpha skeletal muscle Q39596 ACT_OXYRB
91.8 Actin, alpha skeletal muscle P00544 FGR_FSVGR
100.0 Actin, alpha skeletal muscle P10994 ACTS_PLEWA
90.1 Actin, alpha skeletal muscle Q25379 ACT3_LYTPI
96.3 Actin, alpha skeletal muscle Q11212 ACT_SPOLI
93.6 Actin, alpha skeletal muscle Q25381 ACTM_LYTPI
93.8 Actin, alpha skeletal muscle P30170 ACT10_SOLTU
92.9 Actin, alpha skeletal muscle Q92193 ACT_CRAVI
91.7 Actin, alpha skeletal muscle Q92192 ACT_CALFI
91.9 Actin, alpha skeletal muscle Q03342 ACT3_ECHGR
90.5 Actin, alpha skeletal muscle P93375 ACT7_TOBAC
92.4 Actin, alpha skeletal muscle P18602 ACT3_ARTSX
90.6 Actin, alpha skeletal muscle Q55EU6 ACT23_DICDI
93.9 Actin, alpha skeletal muscle P84856 ACTB_CHLPG
90.7 Actin, alpha skeletal muscle P12431 ACTM_STRPU
90.9 Actin, alpha skeletal muscle Q00215 ACTC_STYPL
90.4 Actin, alpha skeletal muscle Q553U6 ACT22_DICDI
91.2 Actin, alpha skeletal muscle Q54GX7 ACT10_DICDI
90.9 Actin, alpha skeletal muscle P07830 ACT1_DICDI
90.3 A Actin, alpha skeletal muscle O65315 ACT_COLSC
91.7 Actin, alpha skeletal muscle P41112 ACT1_PODCA
91.7 Actin, alpha skeletal muscle P02576 ACTA_PHYPO
90.8 A Actin, alpha skeletal muscle P53457 ACT3_DIPDE
92.0 Actin, alpha skeletal muscle P53474 ACTE_STRPU
92.0 Actin, alpha skeletal muscle Q07903 ACTC_STRPU
91.5 Actin, alpha skeletal muscle P53465 ACT1_LYTPI
91.8 Actin, alpha skeletal muscle P53466 ACT2_LYTPI
92.0 Actin, alpha skeletal muscle P92176 ACT2_LUMTE
92.3 Actin, alpha skeletal muscle P18499 ACTF_STRPU
92.0 Actin, alpha skeletal muscle P53473 ACTB_STRPU
92.0 Actin, alpha skeletal muscle P41113 ACT3_PODCA
92.3 Actin, alpha skeletal muscle P10990 ACT1_MESFR
92.8 Actin, alpha skeletal muscle P02578 ACT1_ACACA
93.2 Actin, alpha skeletal muscle P53458 ACT5_DIPDE
92.0 Actin, alpha skeletal muscle P02574 ACT4_DROME
91.8 Actin, alpha skeletal muscle P53461 ACTC_HALRO
92.3 Actin, alpha skeletal muscle P69005 ACTD_STRPU
92.3 Actin, alpha skeletal muscle P69004 ACT2_MESFR
92.3 Actin, alpha skeletal muscle O17320 ACT_CRAGI
91.8 Actin, alpha skeletal muscle P41341 ACTY_LIMPO
92.3 Actin, alpha skeletal muscle P49128 ACT1_AEDAE
92.2 Actin, alpha skeletal muscle O17503 ACTC_BRALA
92.3 Actin, alpha skeletal muscle P18601 ACT2_ARTSX
93.0 Actin, alpha skeletal muscle P91754 ACT_LUMRU
92.3 Actin, alpha skeletal muscle P53472 ACTA_STRPU
92.6 Actin, alpha skeletal muscle P45887 ACT5_BACDO
92.6 Actin, alpha skeletal muscle P07837 ACT2_BOMMO
92.8 Actin, alpha skeletal muscle O16808 ACT_MAYDE
93.0 Actin, alpha skeletal muscle P84336 ACTB_CAMDR
92.0 Actin, alpha skeletal muscle P53470 ACT1_SCHMA
92.6 Actin, alpha skeletal muscle P83968 ACT6_DROSI
92.6 Actin, alpha skeletal muscle P83967 ACT6_DROME
92.2 Actin, alpha skeletal muscle P53456 ACT2_DIPDE
92.6 Actin, alpha skeletal muscle P83969 ACT1_BACDO
92.6 Actin, alpha skeletal muscle P07836 ACT1_BOMMO
92.3 Actin, alpha skeletal muscle P18600 ACT1_ARTSX
93.6 Actin, alpha skeletal muscle P17126 ACT_HYDVU
92.8 Actin, alpha skeletal muscle P53501 ACT3_DROME
92.5 Actin, alpha skeletal muscle P68555 ACT_TAESO
92.8 Actin, alpha skeletal muscle O18500 ACT2_SACKO
92.8 Actin, alpha skeletal muscle P69003 ACT1_HELTB
92.8 Actin, alpha skeletal muscle P69002 ACT1_HELER
92.5 Actin, alpha skeletal muscle P68556 ACT1_DIPDE
92.8 Actin, alpha skeletal muscle P49871 ACT_MANSE
93.0 Actin, alpha skeletal muscle P90689 ACT_BRUMA
92.6 Actin, alpha skeletal muscle P92179 ACTC_BIOGL
93.3 Actin, alpha skeletal muscle P63256 ACTG_ANSAN
93.1 Actin, alpha skeletal muscle P17304 ACTM_APLCA
92.8 Actin, alpha skeletal muscle P53471 ACT2_SCHMA
93.1 Actin, alpha skeletal muscle P45885 ACT2_BACDO
92.6 Actin, alpha skeletal muscle Q964D9 ACTC_PLATR
92.6 Actin, alpha skeletal muscle Q964E3 ACTC_BIOAL
93.3 Actin, alpha skeletal muscle P29751 ACTB_RABIT
93.0 Actin, alpha skeletal muscle Q7ZVI7 ACTB1_DANRE
92.8 Actin, alpha skeletal muscle P12716 ACTC_PISOC
93.0 Actin, alpha skeletal muscle P53485 ACTB2_TAKRU
92.8 Actin, alpha skeletal muscle Q964E0 ACTC_BIOTE
93.3 Actin, alpha skeletal muscle P15475 ACTB_XENBO
93.6 Actin, alpha skeletal muscle P53506 ACT8_XENLA
93.4 Actin, alpha skeletal muscle P10981 ACT5_DROME
93.3 Actin, alpha skeletal muscle Q91ZK5 ACTB_SIGHI
93.3 Actin, alpha skeletal muscle P83750 ACTB_CYPCA
93.3 Actin, alpha skeletal muscle P83751 ACTB_CTEID
93.3 Actin, alpha skeletal muscle Q7ZVF9 ACTB2_DANRE
93.4 Actin, alpha skeletal muscle P45886 ACT3_BACDO
93.3 Actin, alpha skeletal muscle P79818 ACTB_ORYLA
93.3 Actin, alpha skeletal muscle P48975 ACTB_CRIGR
93.3 Actin, alpha skeletal muscle P53478 ACT5_CHICK
93.6 Actin, alpha skeletal muscle Q93131 ACTC_BRAFL
93.4 Actin, alpha skeletal muscle Q964E2 ACTC_BIOPF
93.4 Actin, alpha skeletal muscle Q964E1 ACTC_BIOOB
93.6 Actin, alpha skeletal muscle Q6P378 ACTG_XENTR
93.6 Actin, alpha skeletal muscle Q5JAK2 ACTG_PELLE
93.6 Actin, alpha skeletal muscle P53505 ACT5_XENLA
93.1 Actin, alpha skeletal muscle O18499 ACT1_SACKO
93.6 Actin, alpha skeletal muscle P60707 ACTB_TRIVU
93.6 Actin, alpha skeletal muscle Q4L0Y2 ACTB_SPECI
93.6 Actin, alpha skeletal muscle P60713 ACTB_SHEEP
93.6 Actin, alpha skeletal muscle P60711 ACTB_RAT
93.6 Actin, alpha skeletal muscle Q5R6G0 ACTB_PONAB
93.6 Actin, alpha skeletal muscle Q6QAQ1 ACTB_PIG
93.6 Actin, alpha skeletal muscle Q5R1X3 ACTB_PANTR
93.6 Actin, alpha skeletal muscle P60710 ACTB_MOUSE
93.6 Actin, alpha skeletal muscle Q711N9 ACTB_MESAU
93.6 Actin, alpha skeletal muscle Q4R561 ACTB_MACFA
93.6 Actin, alpha skeletal muscle P60709 ACTB_HUMAN
93.6 Actin, alpha skeletal muscle P60708 ACTB_HORSE
93.6 Actin, alpha skeletal muscle Q76N69 ACTB_CHLAE
93.6 Actin, alpha skeletal muscle P60706 ACTB_CHICK
93.6 Actin, alpha skeletal muscle Q71FK5 ACTB_CAVPO
93.6 Actin, alpha skeletal muscle O18840 ACTB_CANLF
93.6 Actin, alpha skeletal muscle P60712 ACTB_BOVIN
93.9 Actin, alpha skeletal muscle Q93129 ACTC_BRABE
93.6 Actin, alpha skeletal muscle P04829 ACT3_BOMMO
93.1 Actin, alpha skeletal muscle P92182 ACT1_LUMTE
93.9 Actin, alpha skeletal muscle A2BDB0 ACTG_XENLA
93.9 Actin, alpha skeletal muscle P63257 ACTG_TRIVU
93.9 Actin, alpha skeletal muscle P63259 ACTG_RAT
93.9 Actin, alpha skeletal muscle P63260 ACTG_MOUSE
93.9 Actin, alpha skeletal muscle P63261 ACTG_HUMAN
93.9 Actin, alpha skeletal muscle Q5ZMQ2 ACTG_CHICK
93.9 Actin, alpha skeletal muscle P63258 ACTG_BOVIN
93.9 Actin, alpha skeletal muscle Q8JJB8 ACTG_TRISC
93.9 Actin, alpha skeletal muscle O42161 ACTB_SALSA
93.9 Actin, alpha skeletal muscle Q6NVA9 ACTB_XENTR
94.1 Actin, alpha skeletal muscle P68143 ACTB_OREMO
93.9 Actin, alpha skeletal muscle P53486 ACTB3_TAKRU
94.1 Actin, alpha skeletal muscle P68142 ACTB1_TAKRU
93.9 Actin, alpha skeletal muscle Q25010 ACT3A_HELAM
94.1 Actin, alpha skeletal muscle O93400 ACTB_XENLA
93.9 Actin, alpha skeletal muscle P30162 ACT1_ONCVO
94.2 Actin, alpha skeletal muscle P53463 ACTM_HELER
93.9 Actin, alpha skeletal muscle P84185 ACT5C_ANOGA
93.9 Actin, alpha skeletal muscle P84183 ACT4_BOMMO
93.9 Actin, alpha skeletal muscle P84184 ACT3B_HELAM
93.6 Actin, alpha skeletal muscle P02572 ACT2_DROME
93.9 Actin, alpha skeletal muscle P10987 ACT1_DROME
93.9 Actin, alpha skeletal muscle P18603 ACT4_ARTSX
94.2 Actin, alpha skeletal muscle P53464 ACTM_HELTB
94.2 Actin, alpha skeletal muscle P41340 ACT3_LIMPO
95.2 Actin, alpha skeletal muscle Q00214 ACTM_STYPL
93.9 Actin, alpha skeletal muscle P0DM42 ACT3_CAEEL
94.2 Actin, alpha skeletal muscle P10984 ACT2_CAEEL
93.9 Actin, alpha skeletal muscle P0DM41 ACT1_CAEEL
94.2 Actin, alpha skeletal muscle P10986 ACT4_CAEEL
94.7 Actin, alpha skeletal muscle P30163 ACT2_ONCVO
94.7 Actin, alpha skeletal muscle Q26065 ACT_PLAMG
94.9 Actin, alpha skeletal muscle P53467 ACTM_MOLOC
96.0 Actin, alpha skeletal muscle P26198 ACTM_STYCL
96.3 Actin, alpha skeletal muscle P53475 ACTN_STYCL
96.8 Actin, alpha skeletal muscle P53460 ACT1_HALRO
97.1 Actin, alpha skeletal muscle O15998 ACTM_CIOSA
97.1 Actin, alpha skeletal muscle P27130 ACT2_HALRO
97.1 Actin, alpha skeletal muscle Q25472 ACT2_MOLOC
98.4 A Actin, alpha skeletal muscle P63269 ACTH_RAT
98.4 A Actin, alpha skeletal muscle P63268 ACTH_MOUSE
98.4 A Actin, alpha skeletal muscle P63267 ACTH_HUMAN
98.4 A Actin, alpha skeletal muscle P63270 ACTH_CHICK
98.4 A Actin, alpha skeletal muscle Q5E9B5 ACTH_BOVIN
97.6 Actin, alpha skeletal muscle P08023 ACTA_CHICK
97.9 Actin, alpha skeletal muscle P62738 ACTA_RAT
97.9 Actin, alpha skeletal muscle P62740 ACTA_RABIT
97.9 Actin, alpha skeletal muscle P62737 ACTA_MOUSE
97.9 Actin, alpha skeletal muscle P62736 ACTA_HUMAN
97.9 Actin, alpha skeletal muscle P62739 ACTA_BOVIN
98.4 Actin, alpha skeletal muscle Q6P8G3 ACT3_XENTR
98.1 Actin, alpha skeletal muscle P49055 ACTS_CARAU
98.1 Actin, alpha skeletal muscle Q98972 ACTS_ORYLA
98.9 Actin, alpha skeletal muscle P04752 ACT3_XENLA
98.4 Actin, alpha skeletal muscle P68264 ACTS_OREMO
98.4 Actin, alpha skeletal muscle P68140 ACTSA_TAKRU
98.7 Actin, alpha skeletal muscle P04751 ACTC_XENLA
98.7 Actin, alpha skeletal muscle P53482 ACTSB_TAKRU
98.7 Actin, alpha skeletal muscle P53479 ACTS_CYPCA
98.9 Actin, alpha skeletal muscle P53480 ACTC_TAKRU
98.9 Actin, alpha skeletal muscle Q6P640 ACTC_XENTR
98.9 Actin, alpha skeletal muscle P68035 ACTC_RAT
98.9 Actin, alpha skeletal muscle P68033 ACTC_MOUSE
98.9 Actin, alpha skeletal muscle P68032 ACTC_HUMAN
98.9 Actin, alpha skeletal muscle P68034 ACTC_CHICK
98.9 Actin, alpha skeletal muscle Q3ZC07 ACTC_BOVIN
92.8 Actin, alpha skeletal muscle P12717 ACTM_PISOC
92.8 Actin, alpha skeletal muscle Q0PGG4 ACTB_BOSMU
92.3 Actin, alpha skeletal muscle P41339 ACTA_LIMPO
99.2 Actin, alpha skeletal muscle P10995 ACT2_XENLA
99.2 Actin, alpha skeletal muscle P20399 ACT2_XENTR
99.7 Actin, alpha skeletal muscle Q90X97 ACTS_ATRMM
100.0 Actin, alpha skeletal muscle P68136 ACTS_RAT
100.0 Actin, alpha skeletal muscle P68135 ACTS_RABIT
100.0 Actin, alpha skeletal muscle Q5R9Q5 ACTS_PONAB
100.0 Actin, alpha skeletal muscle P68137 ACTS_PIG
100.0 Actin, alpha skeletal muscle P68134 ACTS_MOUSE
100.0 Actin, alpha skeletal muscle P68133 ACTS_HUMAN
100.0 Actin, alpha skeletal muscle P68139 ACTS_CHICK
100.0 Actin, alpha skeletal muscle P68138 ACTS_BOVIN
93.1 D Actin, alpha skeletal muscle P11937 DNAS1_SHEEP
99.2 D Actin, alpha skeletal muscle P00639 DNAS1_BOVIN