Folding of maltose-binding protein. Evidence for the identity of the rate-determining step in vivo and in vitro.
Abstract
The folding of maltose-binding protein, a periplasmic protein in Escherichia coli, was shown to proceed through the same rate-limiting step whether folding occurred in the cell under physiological conditions or in vitro in the absence of other proteins. Four species of maltose-binding protein containing aminoacyl substitutions identified as decreasing the rate of folding of the protein in vivo were purified, and their denaturant-induced folding transitions were analyzed by monitoring the intrinsic fluorescence of tryptophan. In all four cases the rate of folding in vitro was slower than that of the wild-type maltose-binding protein; thus the same step determines the rate of folding in vivo and in vitro. Furthermore, examination of the three-dimensional structure of maltose-binding protein as determined by x-ray crystallography (F. Quiocho, personal communication; Spurlino, J. C., Lu, G.-Y., and Quiocho, F. A. (1991) J. Biol. Chem. 266, 5202-5219) indicates that all 4 of the residues identified as crucial to folding lie in one structural element of the native protein. We conclude that the rate-limiting step both in vivo and in vitro involves formation of this element of structure. Study holds ProTherm entries: 5226, 5227, 5228, 5229, 5230, 5231, 5232 Extra Details: periplasmic protein; rate-limiting step; folding transitions;,structural element
Submission Details
ID: ADyrbQZt3
Submitter: Connie Wang
Submission Date: April 24, 2018, 8:29 p.m.
Version: 1
Publication Details
Chun SY;Strobel S;Bassford P;Randall LL,J. Biol. Chem. (1993) Folding of maltose-binding protein. Evidence for the identity of the rate-determining step in vivo and in vitro. PMID:8407916Additional Information
Study Summary
Structure view and single mutant data analysis
Study data
| Colors: | D | E | R | H | K | S | T | N | Q | A | V | I | L | M | F | Y | W | C | G | P |
|---|
Data Distribution
Studies with similar sequences (approximate matches)
Correlation with other assays (exact sequence matches)
Relevant PDB Entries
| Structure ID | Release Date | Resolution | Structure Title |
|---|---|---|---|
| 2H25 | 2006-10-31 | Solution Structure of Maltose Binding Protein complexed with beta-cyclodextrin | |
| 1EZP | 2001-05-08 | GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS | |
| 5JTQ | 2016-08-24 | The structure of chaperone SecB in complex with unstructured MBP binding site d | |
| 2N44 | 2015-07-01 | EC-NMR Structure of Escherichia coli Maltose-binding protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target ER690 | |
| 5ZR0 | 2018-08-22 | Solution structure of peptidyl-prolyl cis/trans isomerase domain of Trigger Factor in complex with MBP | |
| 2MV0 | 2014-12-10 | Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690 | |
| 2D21 | 2006-03-07 | NMR Structure of stereo-array isotope labelled (SAIL) maltodextrin-binding protein (MBP) | |
| 2V93 | 2007-11-06 | EQUILLIBRIUM MIXTURE OF OPEN AND PARTIALLY-CLOSED SPECIES IN THE APO STATE OF MALTODEXTRIN-BINDING PROTEIN BY PARAMAGNETIC RELAXATION ENHANCEMENT NMR | |
| 2KLF | 2009-10-06 | PERE NMR structure of maltodextrin-binding protein | |
| 2N45 | 2015-07-01 | EC-NMR Structure of Escherichia coli Maltose-binding protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data with a second set of RDC data simulated for an alternative alignment tensor. Northeast Structural Genomics Consortium target ER690 | |
| 5JTR | 2016-08-24 | The structure of chaperone SecB in complex with unstructured MBP binding site e | |
| 1EZO | 2001-05-03 | GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN | |
| 4EXK | 2012-08-08 | 1.28 | A chimera protein containing MBP fused to the C-terminal domain of the uncharacterized protein STM14_2015 from Salmonella enterica |
| 3Q27 | 2011-06-01 | 1.3 | Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP) |
| 5M13 | 2017-11-15 | 1.37 | Synthetic nanobody in complex with MBP |
| 5H7Q | 2017-02-15 | 1.45 | Crystal structure of human MNDA PYD domain with MBP tag |
| 4IRL | 2013-08-07 | 1.47 | X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein |
| 3MP6 | 2011-05-04 | 1.48 | Complex Structure of Sgf29 and dimethylated H3K4 |
| 6SJA | 2019-09-04 | 1.5 | Structure of HPV16 E6 oncoprotein in complex with IRF3 LxxLL motif |
| 3O3U | 2010-10-13 | 1.5 | Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) |
| 3KJT | 2010-02-09 | 1.5 | Stimulation of the maltose transporter by a mutant sucrose binding protein gives insights into ABC transporter coupling |
| 6K7E | 2019-09-18 | 1.53 | Crystal structure of MBPapo-Tim21 fusion protein with a 17-residue helical linker |
| 3Q26 | 2011-06-01 | 1.54 | Cyrstal structure of human alpha-synuclein (10-42) fused to maltose binding protein (MBP) |
| 4WMU | 2015-05-06 | 1.55 | STRUCTURE OF MBP-MCL1 BOUND TO ligand 2 AT 1.55A |
| 3SEW | 2011-09-21 | 1.55 | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) |
| 3Q28 | 2011-06-01 | 1.6 | Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP) |
| 6ZHO | 2020-07-15 | 1.6 | Crystal structure of a CGRP receptor ectodomain heterodimer with bound high affinity inhibitor |
| 5M14 | 2017-11-15 | 1.6 | Synthetic nanobody in complex with MBP |
| 6L0Z | 2019-10-16 | 1.6 | The crystal structure of Salmonella enterica sugar-binding protein MalE |
| 6L3E | 2019-10-23 | 1.6 | Crystal structure of Salmonella enterica sugar-binding protein MalE |
| 4EDQ | 2013-03-20 | 1.64 | MBP-fusion protein of myosin-binding protein c residues 149-269 |
| 5WQ6 | 2017-02-15 | 1.65 | Crystal Structure of hMNDA-PYD with MBP tag |
| 6WBJ | 2020-06-17 | 1.65 | High resolution crystal structure of mRECK(CC4) in fusion with engineered MBP |
| 1ANF | 1997-12-24 | 1.67 | MALTODEXTRIN BINDING PROTEIN WITH BOUND MALTOSE |
| 5VAW | 2018-03-28 | 1.69 | Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii AB5075 |
| 4XHS | 2016-01-27 | 1.7 | Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction |
| 6QXJ | 2019-08-07 | 1.7 | Structure of MBP-Mcl-1 in complex with compound 6a |
| 5AZ8 | 2016-01-13 | 1.7 | Crystal structure of MBP-Tom20 fusion protein tethered with ALDH presequence via a disulfide bond |
| 3MBP | 1997-12-24 | 1.7 | MALTODEXTRIN-BINDING PROTEIN WITH BOUND MALTOTRIOSE |
| 4RG5 | 2015-07-01 | 1.7 | Crystal Structure of S. Pombe SMN YG-Dimer |
| 4MBP | 1998-02-25 | 1.7 | MALTODEXTRIN BINDING PROTEIN WITH BOUND MALTETROSE |
| 4PE2 | 2015-01-14 | 1.72 | MBP PilA1 CD160 |
| 3G7W | 2009-06-23 | 1.75 | Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein |
| 6SIV | 2019-08-21 | 1.75 | Structure of HPV16 E6 oncoprotein in complex with mutant IRF3 LxxLL motif |
| 4QVH | 2014-12-17 | 1.75 | Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein |
| 3JYR | 2010-02-16 | 1.75 | Crystal structures of the GacH receptor of Streptomyces glaucescens GLA.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of Salmonella typhimurium. |
| 6N84 | 2019-07-10 | 1.75 | MBP-fusion protein of transducin-alpha residues 327-350 |
| 4RWF | 2015-05-20 | 1.76 | Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin |
| 5CFV | 2016-07-13 | 1.8 | Fusion of Maltose-binding Protein and PilA from Acinetobacter nosocomialis M2 |
| 3N94 | 2011-06-08 | 1.8 | Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain |
| 6QGD | 2019-06-12 | 1.8 | Structure of human Mcl-1 in complex with thienopyrimidine inhibitor |
| 5ZCA | 2018-08-15 | 1.8 | Crystal structure of lambda repressor (1-20) fused with maltose-binding protein |
| 3CSG | 2008-07-22 | 1.8 | Crystal Structure of Monobody YS1(MBP-74)/Maltose Binding Protein Fusion Complex |
| 1DMB | 1993-10-31 | 1.8 | REFINED 1.8 ANGSTROMS STRUCTURE REVEALS THE MECHANISM OF BINDING OF A CYCLIC SUGAR, BETA-CYCLODEXTRIN, TO THE MALTODEXTRIN BINDING PROTEIN |
| 1LLS | 2002-09-18 | 1.8 | CRYSTAL STRUCTURE OF UNLIGANDED MALTOSE BINDING PROTEIN WITH XENON |
| 6K7F | 2019-09-18 | 1.8 | Crystal structure of MBPholo-Tim21 fusion protein with a 17-residue helical linker |
| 3W15 | 2013-07-03 | 1.8 | Structure of peroxisomal targeting signal 2 (PTS2) of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase in complex with Pex7p and Pex21p |
| 1YTV | 2005-04-12 | 1.8 | Maltose-binding protein fusion to a C-terminal fragment of the V1a vasopressin receptor |
| 5II5 | 2017-06-14 | 1.8 | Crystal structure of red abalone VERL repeat 1 at 1.8 A resolution |
| 1OMP | 1994-01-31 | 1.8 | CRYSTALLOGRAPHIC EVIDENCE OF A LARGE LIGAND-INDUCED HINGE-TWIST MOTION BETWEEN THE TWO DOMAINS OF THE MALTODEXTRIN-BINDING PROTEIN INVOLVED IN ACTIVE TRANSPORT AND CHEMOTAXIS |
| 5AZ9 | 2016-01-13 | 1.82 | Crystal structure of (5-residue deleted)MBP-Tom20 fusion protein tethered with ALDH presequence via a disulfide bond |
| 6V2E | 2020-08-05 | 1.83 | Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant |
| 3SEU | 2011-09-21 | 1.85 | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form III) |
| 3RUM | 2012-06-06 | 1.85 | New strategy to analyze structures of glycopeptide antibiotic-target complexes |
| 1LAX | 2003-03-04 | 1.85 | CRYSTAL STRUCTURE OF MALE31, A DEFECTIVE FOLDING MUTANT OF MALTOSE-BINDING PROTEIN |
| 5H7N | 2017-02-15 | 1.85 | Crystal structure of human NLRP12-PYD with a MBP tag |
| 3SEY | 2011-09-21 | 1.85 | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) |
| 4WGI | 2014-11-19 | 1.85 | A Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1) |
| 3G7V | 2009-06-23 | 1.86 | Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein |
| 5AQ9 | 2016-03-23 | 1.86 | DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography |
| 1JVY | 2001-09-12 | 1.9 | Maltodextrin-binding protein variant D207C/A301GS/P316C with beta-mercaptoethanol mixed disulfides |
| 1FQA | 2001-03-14 | 1.9 | STRUCTURE OF MALTOTETRAITOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P2(1)CRYSTAL FORM |
| 4WMS | 2015-05-06 | 1.9 | STRUCTURE OF APO MBP-MCL1 AT 1.9A |
| 4WVI | 2015-09-23 | 1.9 | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep2). |
| 4TSM | 2015-01-14 | 1.9 | MBP-fusion protein of PilA1 from C. difficile R20291 residues 26-166 |
| 1EZ9 | 2002-01-30 | 1.9 | STRUCTURE OF MALTOTETRAITOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P1 CRYSTAL FORM |
| 3OSQ | 2011-10-26 | 1.9 | Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 175 |
| 5M15 | 2017-11-15 | 1.9 | Synthetic nanobody in complex with MBP |
| 1FQB | 2001-03-14 | 1.9 | STRUCTURE OF MALTOTRIOTOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P2(1)CRYSTAL FORM |
| 5B3Y | 2016-10-26 | 1.9 | Crystal structure of hPin1 WW domain (5-23) fused with maltose-binding protein |
| 1Y4C | 2005-02-15 | 1.9 | Designed Helical Protein fusion MBP |
| 1MDQ | 1994-11-01 | 1.9 | REFINED STRUCTURES OF TWO INSERTION(SLASH)DELETION MUTANTS PROBE FUNCTION OF THE MALTODEXTRIN BINDING PROTEIN |
| 4GLI | 2012-10-17 | 1.9 | Crystal Structure of Human SMN YG-Dimer |
| 3Q25 | 2011-06-01 | 1.9 | Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) |
| 3WAI | 2013-07-17 | 1.9 | Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (AfAglB-L, O29867_ARCFU) from Archaeoglobus fulgidus as a MBP fusion |
| 3SES | 2011-09-21 | 1.9 | Cu-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization |
| 3SET | 2011-09-21 | 1.9 | Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) |
| 4WMW | 2015-05-06 | 1.9 | The structure of MBP-MCL1 bound to ligand 5 at 1.9A |
| 3MP8 | 2011-05-04 | 1.92 | Crystal structure of Sgf29 tudor domain |
| 5C7R | 2015-09-30 | 1.94 | Revealing surface waters on an antifreeze protein by fusion protein crystallography |
| 3H3G | 2009-08-11 | 1.94 | Crystal structure of the extracellular domain of the human parathyroid hormone receptor (PTH1R) in complex with parathyroid hormone-related protein (PTHrP) |
| 2XZ3 | 2011-03-02 | 1.95 | BLV TM hairpin |
| 3SEX | 2011-09-21 | 1.95 | Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) |
| 4KYC | 2013-09-25 | 1.95 | Structure of the C-terminal domain of the Menangle virus phosphoprotein, fused to MBP. |
| 4WVJ | 2015-09-23 | 1.95 | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with an inhibitor peptide (pep3). |
| 5BJZ | 2018-01-17 | 1.95 | Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody |
| 5T0A | 2017-02-01 | 1.95 | Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate |
| 5T05 | 2017-02-01 | 1.95 | Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate |
| 3C4M | 2008-04-08 | 1.95 | Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R) |
| 5AZ7 | 2016-01-13 | 1.96 | Crystal structure of MBP-Tom20 fusion protein with a 4-residue spacer in the connector helix |
| 5GRU | 2016-10-12 | 1.96 | Structure of mono-specific diabody |
| 3EHU | 2008-09-30 | 1.96 | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF |
| 4XA2 | 2016-01-20 | 1.98 | Structure of the Major Type IV pilin of Acinetobacter baumannii |
| 4EGC | 2013-02-27 | 1.99 | Crystal Structure of MBP-fused Human Six1 Bound to Human Eya2 Eya Domain |
| 4IFP | 2013-04-03 | 1.99 | X-ray Crystal Structure of Human NLRP1 CARD Domain |
| 3CSB | 2008-07-22 | 2.0 | Crystal Structure of Monobody YSX1/Maltose Binding Protein Fusion Complex |
| 3HPI | 2010-02-09 | 2.0 | Crystal structure of maltose-binding protein mutant with bound sucrose |
| 1JW4 | 2002-01-30 | 2.0 | Structure of ligand-free maltodextrin-binding protein |
| 3OSR | 2011-10-26 | 2.0 | Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 311 |
| 1JW5 | 2002-01-30 | 2.0 | Structure of Maltose Bound to Open-form Maltodextrin-binding Protein in P1 Crystal |
| 6LES | 2019-12-11 | 2.0 | 3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the focal adhesion kinase |
| 5BMY | 2016-10-26 | 2.0 | Crystal structure of hPin1 WW domain (5-21) fused with maltose-binding protein |
| 5TTD | 2017-03-01 | 2.0 | Minor pilin FctB from S. pyogenes with engineered intramolecular isopeptide bond |
| 6YBK | 2020-11-18 | 2.0 | Structure of MBP-Mcl-1 in complex with compound 4d |
| 5II4 | 2017-06-14 | 2.0 | Crystal structure of red abalone VERL repeat 1 with linker at 2.0 A resolution |
| 1ZIU | 2005-12-20 | 2.0 | Crystal Structure of nickel-bound engineered Maltose Binding Protein |
| 1ZJL | 2005-12-20 | 2.0 | Crystal structure of zinc-bound engineered maltose binding protein |
| 3LC8 | 2011-02-16 | 2.0 | Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-free form) |
| 4YS9 | 2016-03-09 | 2.0 | Ataxin-3 Carboxy-Terminal Region - Crystal C1 (tetragonal) |
| 2OK2 | 2007-04-10 | 2.0 | MutS C-terminal domain fused to Maltose Binding Protein |
| 5WPZ | 2017-02-15 | 2.0 | Crystal structure of MNDA PYD with MBP tag |
| 4R0Y | 2014-09-10 | 2.0 | Structure of Maltose-binding Protein Fusion with the C-terminal GH1 domain of Guanylate Kinase-associated Protein from Rattus norvegicus |
| 6K7D | 2019-09-18 | 2.0 | Crystal structure of MBPapo-Tim21 fusion protein with a 16-residue helical linker |
| 6KI0 | 2020-07-22 | 2.0 | Crystal Structure of Human ASC-CARD |
| 4WMX | 2015-05-06 | 2.0 | The structure of MBP-MCL1 bound to ligand 6 at 2.0A |
| 5GPP | 2017-08-09 | 2.0 | Crystal structure of zebrafish ASC PYD domain |
| 1MPB | 1995-10-15 | 2.0 | MALTODEXTRIN-BINDING PROTEIN (MALTOSE-BINDING PROTEIN) MUTANT, WITH ARGININE REPLACING TRYPTOPHAN AT POSITION 230 (TRP-230-ARG) |
| 3WOA | 2015-04-29 | 2.0 | Crystal structure of lambda repressor (1-45) fused with maltose-binding protein |
| 5JON | 2016-11-30 | 2.04 | Crystal structure of the unliganded form of HCN2 CNBD |
| 3VFJ | 2013-01-09 | 2.05 | The structure of monodechloro-teicoplanin in complex with its ligand, using MBP as a ligand carrier |
| 4WVG | 2015-09-23 | 2.05 | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB). |
| 5OSQ | 2017-09-06 | 2.05 | ZP-N domain of mammalian sperm receptor ZP3 (crystal form II, processed in P21221) |
| 5Z0R | 2018-04-11 | 2.05 | Structural insight into the Zika virus capsid encapsulating the viral genome |
| 6D1U | 2018-09-05 | 2.05 | Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer in complex with adrenomedullin 2/intermedin |
| 3VD8 | 2013-01-16 | 2.07 | Crystal structure of human AIM2 PYD domain with MBP fusion |
| 5AZA | 2016-01-13 | 2.08 | Crystal structure of MBP-sAglB fusion protein with a 20-residue spacer in the connector helix |
| 5YGP | 2018-10-03 | 2.09 | Human TNFRSF25 death domain mutant-D412E |
| 5FIO | 2016-11-16 | 2.1 | DARPins as a new tool for experimental phasing in protein crystallography |
| 5K94 | 2017-06-07 | 2.1 | Deletion-Insertion Chimera of MBP with the Preprotein Cross-Linking Domain of the SecA ATPase |
| 5MM3 | 2017-10-25 | 2.1 | Unstructured MamC magnetite-binding protein located between two helices. |
| 5GXV | 2017-07-19 | 2.1 | Crystal structure of PigG |
| 2VGQ | 2007-12-11 | 2.1 | Crystal Structure of Human IPS-1 CARD |
| 5GPQ | 2017-08-09 | 2.1 | Crystal Structure of zebrafish ASC CARD Domain |
| 4WVH | 2015-09-23 | 2.1 | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep1). |
| 3OAI | 2011-12-21 | 2.1 | Crystal structure of the extra-cellular domain of human myelin protein zero |
| 3PGF | 2011-03-09 | 2.1 | Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB) |
| 1MPC | 1995-10-15 | 2.1 | MALTODEXTRIN-BINDING PROTEIN (MALTOSE-BINDING PROTEIN) MUTANT, WITH ARGININE REPLACING TRYPTOPHAN AT POSITION 230 (TRP-230-ARG) |
| 1MH3 | 2002-09-18 | 2.1 | maltose binding-a1 homeodomain protein chimera, crystal form I |
| 6YBL | 2020-11-18 | 2.1 | Structure of MBP-Mcl-1 in complex with compound 9m |
| 5T03 | 2017-02-01 | 2.1 | Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate |
| 6QYO | 2019-08-07 | 2.1 | Structure of MBP-Mcl-1 in complex with compound 18a |
| 1NL5 | 2003-08-12 | 2.1 | Engineered High-affinity Maltose-Binding Protein |
| 4XZS | 2016-01-20 | 2.12 | Crystal Structure of TRIAP1-MBP fusion |
| 5E24 | 2016-06-15 | 2.14 | Structure of the Su(H)-Hairless-DNA Repressor Complex |
| 6SMV | 2019-09-04 | 2.14 | Structure of HPV49 E6 protein in complex with MAML1 LxxLL motif |
| 4H1G | 2012-10-10 | 2.15 | Structure of Candida albicans Kar3 motor domain fused to maltose-binding protein |
| 3LBS | 2011-02-16 | 2.15 | Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound form) |
| 5BK1 | 2018-01-17 | 2.15 | Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody |
| 5ZD4 | 2018-08-29 | 2.17 | Crystal structure of MBP-fused BIL1/BZR1 in complex with double-stranded DNA |
| 1ZKB | 2005-12-20 | 2.2 | Zinc-free Engineered maltose binding protein |
| 3RLF | 2011-08-10 | 2.2 | Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to MgAMPPNP |
| 6QYL | 2019-08-07 | 2.2 | Structure of MBP-Mcl-1 in complex with compound 8a |
| 5IHJ | 2016-09-21 | 2.2 | Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii BIDMC57 |
| 5LOF | 2016-10-26 | 2.2 | Crystal structure of the MBP-MCL1 complex with highly selective and potent inhibitor of MCL1 |
| 4KV3 | 2014-04-09 | 2.2 | Ubiquitin-like domain of the Mycobacterium tuberculosis type VII secretion system protein EccD1 as maltose-binding protein fusion |
| 6QZ7 | 2019-08-07 | 2.2 | Structure of MBP-Mcl-1 in complex with compound 8b |
| 5JST | 2017-03-22 | 2.2 | MBP fused MDV1 coiled coil |
| 4KYD | 2013-09-25 | 2.21 | Partial Structure of the C-terminal domain of the HPIV4B phosphoprotein, fused to MBP. |
| 6OB5 | 2019-12-04 | 2.21 | Computationally-designed, modular sense/response system (S3-2D) |
| 6D66 | 2018-09-19 | 2.23 | Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16 |
| 4OGM | 2015-01-14 | 2.23 | MBP-fusion protein of PilA1 residues 26-159 |
| 1SVX | 2004-05-25 | 2.24 | Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein |
| 5GXT | 2017-07-19 | 2.24 | Crystal structure of PigG |
| 3HST | 2010-04-28 | 2.25 | N-Terminal RNASE H domain of rv2228c from mycobacterium tuberculosis as a fusion protein with maltose binding protein |
| 4WTH | 2016-03-09 | 2.25 | Ataxin-3 Carboxy Terminal Region - Crystal C2 (triclinic) |
| 4XR8 | 2016-02-03 | 2.25 | Crystal structure of the HPV16 E6/E6AP/p53 ternary complex at 2.25 A resolution |
| 4JKM | 2014-09-17 | 2.26 | Crystal Structure of Clostridium perfringens beta-glucuronidase |
| 6NDJ | 2019-01-23 | 2.27 | Crystal structure of human NLRP6 PYD domain with MBP fusion |
| 6ANV | 2017-10-25 | 2.27 | Crystal structure of anti-CRISPR protein AcrF1 |
| 6SQC | 2020-09-30 | 2.28 | Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076 |
| 4DXB | 2012-08-08 | 2.29 | 2.29A structure of the engineered MBP TEM-1 fusion protein RG13 in complex with zinc, P1 space group |
| 6EQZ | 2017-11-01 | 2.29 | A MamC-MIC insertion in MBP scaffold at position K170 |
| 3PY7 | 2011-12-14 | 2.29 | Crystal structure of full-length Bovine Papillomavirus oncoprotein E6 in complex with LD1 motif of paxillin at 2.3A resolution |
| 6QYK | 2019-08-07 | 2.3 | Structure of MBP-Mcl-1 in complex with compound 7a |
| 1MH4 | 2002-09-18 | 2.3 | maltose binding-a1 homeodomain protein chimera, crystal form II |
| 3PUW | 2011-08-10 | 2.3 | Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-AlF4 |
| 3PUX | 2011-08-10 | 2.3 | Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-BeF3 |
| 5B3Z | 2016-10-26 | 2.3 | Crystal structure of hPin1 WW domain (5-39) fused with maltose-binding protein |
| 5DFM | 2015-10-28 | 2.3 | Structure of Tetrahymena telomerase p19 fused to MBP |
| 1MDP | 1994-11-01 | 2.3 | REFINED STRUCTURES OF TWO INSERTION(SLASH)DELETION MUTANTS PROBE FUNCTION OF THE MALTODEXTRIN BINDING PROTEIN |
| 1FQC | 2001-03-14 | 2.3 | CRYSTAL STRUCTURE OF MALTOTRIOTOL BOUND TO CLOSED-FORM MALTODEXTRIN BINDING PROTEIN |
| 1MPD | 1995-10-15 | 2.3 | MALTODEXTRIN-BINDING PROTEIN (MALTOSE-BINDING PROTEIN) MUTANT, WITH ARGININE REPLACING TRYPTOPHAN AT POSITION 230 (TRP-230-ARG), COMPLEXED WITH MALTOSE |
| 3Q29 | 2011-06-01 | 2.3 | Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) |
| 6AEO | 2019-06-12 | 2.3 | TssL periplasmic domain |
| 5CBN | 2016-03-30 | 2.3 | Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS |
| 1FQD | 2001-03-14 | 2.3 | CRYSTAL STRUCTURE OF MALTOTETRAITOL BOUND TO CLOSED-FORM MALTODEXTRIN BINDING PROTEIN |
| 3D4G | 2008-12-02 | 2.3 | ZP-N domain of mammalian sperm receptor ZP3 (crystal form II) |
| 4DXC | 2012-08-08 | 2.3 | Crystal structure of the engineered MBP TEM-1 fusion protein RG13, C2 space group |
| 1HSJ | 2001-06-06 | 2.3 | SARR MBP FUSION STRUCTURE |
| 1NMU | 2003-02-18 | 2.31 | MBP-L30 |
| 5IQZ | 2016-07-27 | 2.33 | Crystal structure of N-terminal domain of Human SIRT7 |
| 3SER | 2011-09-21 | 2.35 | Zn-mediated Polymer of Maltose-binding Protein K26H/K30H by Synthetic Symmetrization |
| 6D65 | 2018-09-19 | 2.35 | Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein off7 |
| 6KEA | 2019-09-11 | 2.35 | crystal structure of MBP-tagged REV7-IpaB complex |
| 4WMT | 2015-05-06 | 2.35 | STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A |
| 3H4Z | 2010-03-31 | 2.35 | Crystal Structure of an MBP-Der p 7 fusion protein |
| 2OBG | 2007-03-27 | 2.35 | Crystal Structure of Monobody MBP-74/Maltose Binding Protein Fusion Complex |
| 4KI0 | 2013-10-23 | 2.38 | Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose |
| 5B3X | 2016-10-26 | 2.4 | Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in P41212 form |
| 3PUV | 2011-08-10 | 2.4 | Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-VO4 |
| 6HD8 | 2019-08-28 | 2.4 | Crystal structure of the potassium channel MtTMEM175 in complex with a Nanobody-MBP fusion protein |
| 5B3W | 2016-10-26 | 2.4 | Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in C2221 form |
| 4MY2 | 2013-11-13 | 2.4 | Crystal Structure of Norrin in fusion with Maltose Binding Protein |
| 5W0R | 2017-08-16 | 2.4 | Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cacodylic acid |
| 3DM0 | 2008-09-09 | 2.4 | Maltose Binding Protein fusion with RACK1 from A. thaliana |
| 4WMV | 2015-05-06 | 2.4 | STRUCTURE OF MBP-MCL1 BOUND TO ligand 4 AT 2.4A |
| 4JBZ | 2013-12-11 | 2.4 | Structure of Mcm10 coiled-coil region |
| 6TZC | 2019-11-20 | 2.41 | Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin |
| 5I04 | 2017-06-07 | 2.42 | Crystal structure of the orphan region of human endoglin/CD105 |
| 4RWG | 2015-05-20 | 2.44 | Crystal structure of the CLR:RAMP1 extracellular domain heterodimer with bound high affinity CGRP analog |
| 6WBH | 2020-06-17 | 2.45 | Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution |
| 4IKM | 2013-05-08 | 2.46 | X-ray structure of CARD8 CARD domain |
| 6APX | 2017-11-01 | 2.49 | Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1 |
| 3A3C | 2009-08-04 | 2.5 | Crystal structure of TIM40/MIA40 fusing MBP, C296S and C298S mutant |
| 4N4X | 2014-09-17 | 2.5 | Crystal Structure of the MBP fused human SPLUNC1 (native form) |
| 6QYN | 2019-08-07 | 2.5 | Structure of MBP-Mcl-1 in complex with compound 10d |
| 1MG1 | 1999-04-06 | 2.5 | HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA |
| 1N3X | 2003-08-12 | 2.5 | Ligand-free High-Affinity Maltose-Binding Protein |
| 1JVX | 2001-09-12 | 2.5 | Maltodextrin-binding protein variant D207C/A301GS/P316C cross-linked in crystal |
| 6N85 | 2019-07-10 | 2.5 | Resistance to inhibitors of cholinesterase 8A (Ric8A) protein in complex with MBP-tagged transducin-alpha residues 327-350 |
| 5YEV | 2018-09-19 | 2.5 | Murine DR3 death domain |
| 1ZMG | 2005-12-20 | 2.5 | Crystal structure of copper-bound engineered maltose binding protein |
| 4KEG | 2014-04-30 | 2.5 | Crystal Structure of MBP Fused Human SPLUNC1 |
| 6YBJ | 2020-11-18 | 2.5 | Structure of MBP-Mcl-1 in complex with compound 3e |
| 5ZNZ | 2019-04-17 | 2.55 | Structure of mDR3 DD with MBP tag mutant-I387V |
| 6D67 | 2018-09-19 | 2.55 | Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16 |
| 4GIZ | 2013-01-23 | 2.55 | Crystal structure of full-length human papillomavirus oncoprotein E6 in complex with LXXLL peptide of ubiquitin ligase E6AP at 2.55 A resolution |
| 5AZ6 | 2016-01-13 | 2.56 | Crystal structure of MBP-Tom20 fusion protein with a 2-residue spacer in the connector helix |
| 4KYE | 2013-09-25 | 2.6 | Partial Structure of the C-terminal domain of the HPIV4B phosphoprotein, fused to MBP. |
| 5BK2 | 2018-01-17 | 2.6 | Crystal structure of maltose binding protein in complex with a peristeric synthetic antibody |
| 1PEB | 2003-08-12 | 2.6 | LIGAND-FREE HIGH-AFFINITY MALTOSE-BINDING PROTEIN |
| 4XAI | 2015-03-04 | 2.6 | Crystal Structure of red flour beetle NR2E1/TLX |
| 1N3W | 2003-08-12 | 2.6 | Engineered High-Affinity Maltose-Binding Protein |
| 3MP1 | 2011-05-04 | 2.6 | Complex structure of Sgf29 and trimethylated H3K4 |
| 3F5F | 2008-12-16 | 2.65 | Crystal structure of heparan sulfate 2-O-sulfotransferase from gallus gallus as a maltose binding protein fusion. |
| 5YGS | 2018-10-03 | 2.69 | Human TNFRSF25 death domain |
| 4LOG | 2013-10-09 | 2.7 | The crystal structure of the orphan nuclear receptor PNR ligand binding domain fused with MBP |
| 6QUG | 2020-05-27 | 2.7 | GHK tagged MBP-Nup98(1-29) |
| 5I69 | 2016-03-23 | 2.7 | MBP-MamC magnetite-interaction component mutant-D70A |
| 1IUD | 1997-06-05 | 2.7 | MALTODEXTRIN-BINDING PROTEIN INSERTION/DELETION MUTANT WITH AN INSERTED B-CELL EPITOPE FROM THE PRES2 REGION OF HEPATITIS B VIRUS |
| 6DM8 | 2018-08-01 | 2.7 | Understanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitors |
| 4O2X | 2014-12-24 | 2.7 | Structure of a malarial protein |
| 5HZV | 2017-06-07 | 2.7 | Crystal structure of the zona pellucida module of human endoglin/CD105 |
| 3OB4 | 2011-02-02 | 2.71 | MBP-fusion protein of the major peanut allergen Ara h 2 |
| 5ZNY | 2019-04-17 | 2.74 | Structure of mDR3_DD-C363G with MBP tag |
| 3EHS | 2008-09-30 | 2.76 | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) |
| 6DKS | 2019-01-02 | 2.78 | Structure of the Rbpj-SHARP-DNA Repressor Complex |
| 5EDU | 2016-07-27 | 2.79 | Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A |
| 5WVN | 2018-01-03 | 2.8 | Crystal structure of MBS-BaeS fusion protein |
| 4FEB | 2013-03-13 | 2.8 | Crystal Structure of Htt36Q3H-EX1-X1-C2(Beta) |
| 6CXS | 2019-04-17 | 2.8 | Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine |
| 5E7U | 2016-03-23 | 2.8 | MBP-MamC loop structure, a magnetite biomineralizing protein from Magnetospirillium magneticum AMB-1 |
| 4NUF | 2014-01-29 | 2.8 | Crystal Structure of SHP/EID1 |
| 5V6Y | 2018-01-31 | 2.8 | Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant |
| 6SLM | 2020-09-09 | 2.8 | Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP |
| 4BLB | 2013-11-27 | 2.8 | Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex |
| 3MQ9 | 2010-10-27 | 2.8 | Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 Fused to MBP |
| 4BLD | 2013-11-27 | 2.8 | Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex |
| 4BL9 | 2013-11-27 | 2.8 | Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I) |
| 2R6G | 2007-11-27 | 2.8 | The Crystal Structure of the E. coli Maltose Transporter |
| 1R6Z | 2004-01-13 | 2.8 | The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion) |
| 4FED | 2013-03-13 | 2.81 | Crystal Structure of Htt36Q3H |
| 6KXG | 2020-09-16 | 2.81 | Crystal structure of caspase-11-CARD |
| 5JJ4 | 2016-06-29 | 2.81 | Crystal Structure of a Variant Human Activation-induced Deoxycytidine Deaminase as an MBP fusion protein |
| 6EG3 | 2018-10-31 | 2.84 | Crystal structure of human BRM in complex with compound 15 |
| 5DIS | 2015-11-04 | 2.85 | Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214 |
| 6DD5 | 2018-10-17 | 2.85 | Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein |
| 4QSZ | 2015-07-08 | 2.86 | Crystal structure of mouse JMJd7 fused with maltose-binding protein |
| 6HDB | 2019-08-28 | 2.9 | Crystal structure of the potassium channel MtTMEM175 with zinc |
| 4KHZ | 2013-10-23 | 2.9 | Crystal structure of the maltose-binding protein/maltose transporter complex in an pre-translocation conformation bound to maltoheptaose |
| 5IIC | 2017-06-14 | 2.9 | Crystal structure of red abalone VERL repeat 3 at 2.9 A resolution |
| 5W0U | 2017-08-16 | 2.9 | Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with dCMP |
| 3PUZ | 2011-05-18 | 2.9 | Crystal Structure of a pre-translocation state MBP-Maltose transporter complex bound to AMP-PNP |
| 1A7L | 1998-06-17 | 2.9 | DOMINANT B-CELL EPITOPE FROM THE PRES2 REGION OF HEPATITIS B VIRUS IN THE FORM OF AN INSERTED PEPTIDE SEGMENT IN MALTODEXTRIN-BINDING PROTEIN |
| 3D4C | 2008-12-02 | 2.9 | ZP-N domain of mammalian sperm receptor ZP3 (crystal form I) |
| 5WVM | 2018-01-03 | 2.9 | Crystal structure of baeS cocrystallized with 2 mM indole |
| 5Z0V | 2018-04-11 | 2.91 | Structural insight into the Zika virus capsid encapsulating the viral genome |
| 6I4Y | 2019-03-20 | 2.91 | X-ray structure of the human mitochondrial PRELID3b-TRIAP1 complex |
| 6M4V | 2020-08-26 | 2.92 | Crystal structure of MBP fused split FKBP in complex with rapamycin |
| 5LEM | 2017-08-02 | 2.98 | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_11_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein |
| 6EG2 | 2018-10-31 | 2.98 | Crystal structure of human BRM in complex with compound 16 |
| 4FEC | 2013-03-13 | 3.0 | Crystal Structure of Htt36Q3H |
| 6DBJ | 2018-08-01 | 3.0 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates |
| 5Y2G | 2019-02-27 | 3.0 | Structure of MBP tagged GBS CAMP |
| 4FE8 | 2013-03-13 | 3.0 | Crystal Structure of Htt36Q3H-EX1-X1-C1(Alpha) |
| 2ZXT | 2009-08-04 | 3.0 | Crystal structure of Tim40/MIA40, a disulfide relay system in mitochondria, solved as MBP fusion protein |
| 4BL8 | 2013-11-27 | 3.04 | Crystal structure of full-length human Suppressor of fused (SUFU) |
| 3SEV | 2011-09-21 | 3.05 | Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization |
| 5LEL | 2017-11-15 | 3.1 | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_10_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein |
| 3PV0 | 2011-05-18 | 3.1 | Crystal Structure of a pre-translocation state MBP-Maltose transporter complex without nucleotide |
| 3EF7 | 2008-12-02 | 3.1 | ZP-N domain of mammalian sperm receptor ZP3 (crystal form III) |
| 3PUY | 2011-05-18 | 3.1 | Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to AMP-PNP after crystal soaking of the pretranslocation state |
| 6M4W | 2020-08-26 | 3.11 | Crystal structure of MBP fused split FKBP-FRB T2098L mutant in complex with rapamycin |
| 5JQE | 2016-10-26 | 3.16 | Crystal structure of caspase8 tDED |
| 5W1C | 2017-08-16 | 3.18 | Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cytidine |
| 4WRN | 2016-01-27 | 3.2 | Crystal structure of the polymerization region of human uromodulin/Tamm-Horsfall protein |
| 6LF3 | 2019-12-11 | 3.2 | 3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the protein-tyrosine kinase 2-beta |
| 6SWR | 2020-04-15 | 3.2 | Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc |
| 6VLS | 2020-07-22 | 3.2 | Structure of C-terminal fragment of Vip3A toxin |
| 4WJV | 2014-11-19 | 3.2 | Crystal structure of Rsa4 in complex with the Nsa2 binding peptide |
| 5FSG | 2016-04-06 | 3.21 | Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation and a template for drug design |
| 1T0K | 2004-07-20 | 3.24 | Joint X-ray and NMR Refinement of Yeast L30e-mRNA complex |
| 3L2J | 2010-02-02 | 3.24 | Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R) |
| 4B3N | 2012-10-24 | 3.3 | Crystal structure of rhesus TRIM5alpha PRY/SPRY domain |
| 6DBI | 2018-08-01 | 3.4 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates |
| 4PQK | 2014-06-18 | 3.4 | C-Terminal domain of DNA binding protein |
| 6HDC | 2019-08-28 | 3.4 | Crystal structure of the potassium channel MtTMEM175 T38A variant in complex with a Nanobody-MBP fusion protein |
| 3EHT | 2008-09-30 | 3.4 | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF |
| 4NDZ | 2014-03-19 | 3.45 | Structure of Maltose Binding Protein fusion to 2-O-Sulfotransferase with bound heptasaccharide and PAP |
| 6HD9 | 2019-08-28 | 3.5 | Crystal structure of the potassium channel MtTMEM175 with rubidium |
| 3IOT | 2009-09-29 | 3.5 | Huntingtin amino-terminal region with 17 Gln residues - crystal C92-b |
| 4BLA | 2013-11-27 | 3.5 | Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form II) |
| 3IOW | 2009-09-29 | 3.5 | Huntingtin amino-terminal region with 17 Gln residues - crystal C99-Hg |
| 4XAJ | 2015-03-04 | 3.55 | Crystal structure of human NR2E1/TLX |
| 4XZV | 2016-01-20 | 3.58 | Crystal Structure of SLMO1-TRIAP1 Complex |
| 5GS2 | 2016-10-12 | 3.59 | Crystal structure of diabody complex with repebody and MBP |
| 3IOR | 2009-09-29 | 3.6 | Huntingtin amino-terminal region with 17 Gln residues - crystal C95 |
| 5W0Z | 2017-08-16 | 3.61 | Crystal structure of MBP fused activation-induced cytidine deaminase (AID) |
| 3IO4 | 2009-10-27 | 3.63 | Huntingtin amino-terminal region with 17 Gln residues - Crystal C90 |
| 3IO6 | 2009-10-27 | 3.7 | Huntingtin amino-terminal region with 17 Gln residues - crystal C92-a |
| 3IOV | 2009-09-29 | 3.7 | Huntingtin amino-terminal region with 17 Gln residues - crystal C99 |
| 3IOU | 2009-09-29 | 3.7 | Huntingtin amino-terminal region with 17 Gln residues - crystal C94 |
| 6HDA | 2019-08-28 | 3.8 | Crystal structure of the potassium channel MtTMEM175 with cesium |
| 5CL1 | 2015-08-12 | 3.8 | Complex structure of Norrin with human Frizzled 4 |
| 6DBU | 2018-08-01 | 3.9 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs |
| 6BUZ | 2017-12-20 | 3.92 | Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N |
| 6DBR | 2018-08-01 | 4.0 | Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS |
| 6P6W | 2019-08-14 | 4.0 | Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state |
| 6DBX | 2018-08-01 | 4.2 | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA |
| 6DBQ | 2018-08-01 | 4.22 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs |
| 3J9P | 2015-04-08 | 4.24 | Structure of the TRPA1 ion channel determined by electron cryo-microscopy |
| 6DBV | 2018-08-01 | 4.29 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs |
| 6DBT | 2018-08-01 | 4.3 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs |
| 6DBO | 2018-08-01 | 4.4 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs |
| 5HZW | 2017-06-07 | 4.45 | Crystal structure of the orphan region of human endoglin/CD105 in complex with BMP9 |
| 6DBW | 2018-08-01 | 4.7 | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA |
| 6DBL | 2018-08-01 | 5.0 | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs |
| 5LDF | 2016-08-10 | 6.2 | Maltose binding protein genetically fused to dodecameric glutamine synthetase |
Relevant UniProtKB Entries
| Percent Identity | Matching Chains | Protein | Accession | Entry Name |
|---|---|---|---|---|
| 90.7 | Maltose-binding periplasmic protein | P41130 | MALE_PHOLU | |
| 93.9 | Maltose-binding periplasmic protein | P18815 | MALE_KLEAE | |
| 94.3 | Maltose-binding periplasmic protein | P19576 | MALE_SALTY | |
| 100.0 | Maltose-binding periplasmic protein | P0AEX9 | MALE_ECOLI | |
| 100.0 | Maltose-binding periplasmic protein | P0AEY0 | MALE_ECO57 |