Evaluation of the energetic contribution of an ionic network to beta-sheet stability


Abstract

We have evaluated the interaction energy of a three-residue ionic network constructed on the ’β-sheet surface of protein G using double mutant cycles. Although the two individual ion pairs were each stabilizing by ∼0.6 kcal/mol, the excess gain in stability for the triad was small (0.06 kcal/mol).

Submission Details

ID: 7Pjwp2Ry

Submitter: Marie Ary

Submission Date: March 21, 2017, 3:49 p.m.

Version: 2

Publication Details
Lassila KS;Datta D;Mayo SL,Protein Sci (2002) Evaluation of the energetic contribution of an ionic network to beta-sheet stability. PMID:11847291
Additional Information

Sequence Assay Result Units