Low-temperature unfolding of a mutant of phage T4 lysozyme. 1. Equilibrium studies.
Abstract
The mutant protein I3C-C97/C54T of phage T4 lysozyme is free of sulfhydryl groups and has a genetically engineered disulfide bridge between positions 3 and 97 (Perry & Wetzel, 1986). This protein has a maximum stability at 12 degrees C in 3 M guanidinium chloride and undergoes reversible high- and low-temperature melting at 28 and -3 degrees C, respectively, in this medium. The free energy of stabilization of the protein has been studied over a range of temperature that includes both melting transitions. The stability curve fits a constant delta Cp model over the entire range, permitting an unusually complete determination of the thermodynamic parameters of the protein and demonstrating that the low-temperature unfolded form of the protein may be interpreted as an extrapolation with constant delta Cp of the high-temperature unfolded form. The free energy of unfolding is a linear function of guanidinium concentration within experimental error which permits a rough estimate of the stability of the protein at low temperatures and of the differential interaction of the unfolded protein with guanidinium chloride. These equilibrium studies provide a basis for the interpretation of the kinetic studies reported in the following paper. Study holds ProTherm entries: 3831, 3832, 3833, 3834 Extra Details: low-temperature unfolding; equilibrium studies;,stability curve; constant delta Cp model
Submission Details
ID: 2Nq7CpSt
Submitter: Connie Wang
Submission Date: April 24, 2018, 8:22 p.m.
Version: 1
Publication Details
Chen BL;Schellman JA,Biochemistry (1989) Low-temperature unfolding of a mutant of phage T4 lysozyme. 1. Equilibrium studies. PMID:2653427Additional Information
Study Summary
Structure view and single mutant data analysis
Study data
| Colors: | D | E | R | H | K | S | T | N | Q | A | V | I | L | M | F | Y | W | C | G | P |
|---|
Data Distribution
Studies with similar sequences (approximate matches)
Correlation with other assays (exact sequence matches)
Relevant PDB Entries
| Structure ID | Release Date | Resolution | Structure Title |
|---|---|---|---|
| 2LC9 | 2011-08-17 | Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant | |
| 5XPE | 2017-10-04 | Neutron structure of the T26H mutant of T4 lysozyme | |
| 2LCB | 2011-08-17 | Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant | |
| 2O7A | 2007-04-10 | 0.84 | T4 lysozyme C-terminal fragment |
| 5JDT | 2016-09-28 | 1.0 | Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K |
| 5XPF | 2017-10-04 | 1.04 | High-resolution X-ray structure of the T26H mutant of T4 lysozyme |
| 6BG3 | 2018-09-26 | 1.05 | Structure of (3S,4S)-1-benzyl-4-(3-(3-(trifluoromethyl)phenyl)ureido)piperidin-3-yl acetate bound to DCN1 |
| 1SWZ | 2005-01-18 | 1.06 | Use of an ion-binding site to bypass the 1000-atom limit to ab initio structure determination by direct methods |
| 1SWY | 2004-11-23 | 1.06 | Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination |
| 1SX2 | 2004-11-23 | 1.06 | Use of a Halide Binding Site to Bypass the 1000-atom Limit to Structure Determination by Direct Methods |
| 1SX7 | 2004-11-30 | 1.06 | Use of an ion-binding site to bypass the 1000-atom limit to ab initio structure determination by direct methods |
| 3F8V | 2009-02-17 | 1.08 | Evaulaution at Atomic Resolution of the Role of Strain in Destabilizing the Temperature Sensitive T4 Lysozyme Mutant Arg96-->His |
| 3FA0 | 2009-02-17 | 1.09 | Evaulaution at Atomic Resolution of the Role of Strain in Destabilizing the Temperature Sensitive T4 Lysozyme Mutant Arg96-->His |
| 6BG5 | 2018-09-26 | 1.1 | Structure of 1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-(1-propylpiperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea bound to DCN1 |
| 5LWO | 2017-03-08 | 1.18 | Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at 100K |
| 3F9L | 2009-02-17 | 1.19 | Evaulaution at Atomic Resolution of the Role of Strain in Destabilizing the Temperature Sensitive T4 Lysozyme Mutant Arg96-->His |
| 3FAD | 2009-02-17 | 1.2 | Evaulaution at Atomic Resolution of the Role of Strain in Destabilizing the Temperature Sensitive T4 Lysozyme Mutant Arg96-->His |
| 3HH3 | 2009-10-13 | 1.25 | New azaborine compounds bind to the T4 lysozyme L99A cavity - 1,2-dihydro-1,2-azaborine |
| 3HH4 | 2009-10-13 | 1.25 | New azaborine compounds bind to the T4 lysozyme L99A cavity - Benzene as control |
| 3HH6 | 2009-10-13 | 1.25 | New azaborine compounds bind to the T4 lysozyme L99A cavity -ethylbenzene as control |
| 3DKE | 2008-11-25 | 1.25 | Polar and non-polar cavities in phage T4 lysozyme |
| 3HH5 | 2009-10-13 | 1.25 | New azaborine compounds bind to the T4 lysozyme L99A cavity - 1-ethyl-2-hydro-1,2-azaborine |
| 3HTG | 2009-11-03 | 1.26 | 2-ethoxy-3,4-dihydro-2h-pyran in complex with T4 lysozyme L99A/M102Q |
| 3HUK | 2009-11-03 | 1.29 | Benzylacetate in complex with T4 lysozyme L99A/M102Q |
| 2RBN | 2008-03-18 | 1.29 | N-phenylglycinonitrile in complex with T4 lysozyme L99A/M102Q |
| 2RBO | 2008-03-18 | 1.29 | 2-nitrothiophene in complex with T4 lysozyme L99A/M102Q |
| 4E97 | 2012-09-05 | 1.3 | T4 Lysozyme L99A/M102H with 2-Mercaptoethanol Bound |
| 5JWV | 2016-09-21 | 1.3 | T4 Lysozyme L99A/M102Q with Ethylbenzene Bound |
| 6D9M | 2019-04-10 | 1.35 | T4-Lysozyme fusion to Geobacter GGDEF |
| 5V7D | 2018-06-20 | 1.35 | T4 lysozyme Y18Ymbr |
| 5V7E | 2018-06-20 | 1.36 | T4 lysozyme Y18Ymcl |
| 5V86 | 2017-05-24 | 1.37 | Structure of DCN1 bound to NAcM-OPT |
| 4W59 | 2015-04-01 | 1.39 | T4 Lysozyme L99A with n-Hexylbenzene Bound |
| 3HTD | 2009-11-03 | 1.4 | (Z)-Thiophene-2-carboxaldoxime in complex with T4 lysozyme L99A/M102Q |
| 2IGC | 2007-06-12 | 1.4 | Structure of Spin labeled T4 Lysozyme Mutant T115R1A |
| 3HUA | 2009-11-03 | 1.4 | 4,5,6,7-tetrahydroindole in complex with T4 lysozyme L99A/M102Q |
| 2NTG | 2007-06-12 | 1.4 | Structure of Spin-labeled T4 Lysozyme Mutant T115R7 |
| 3RUN | 2012-06-06 | 1.4 | New strategy to analyze structures of glycopeptide antibiotic-target complexes |
| 2Q9D | 2007-06-26 | 1.4 | Structure of spin-labeled T4 lysozyme mutant A41R1 |
| 5JWT | 2016-09-21 | 1.41 | T4 Lysozyme L99A/M102Q with Benzene Bound |
| 2RBR | 2008-03-18 | 1.43 | 2-phenoxyethanol in complex with T4 lysozyme L99A/M102Q |
| 3SBB | 2011-09-21 | 1.43 | Disulphide-mediated Tetramer of T4 Lysozyme R76C/R80C by Synthetic Symmetrization |
| 4W51 | 2015-04-01 | 1.45 | T4 Lysozyme L99A with No Ligand Bound |
| 2F2Q | 2006-04-25 | 1.45 | High resolution crystal strcuture of T4 lysozyme mutant L20R63/A liganded to guanidinium ion |
| 3GUI | 2009-08-25 | 1.45 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Apo structure |
| 1LW9 | 2003-05-20 | 1.45 | Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability |
| 1P36 | 2003-10-07 | 1.45 | T4 LYOSZYME CORE REPACKING MUTANT I100V/TA |
| 3HUQ | 2009-11-03 | 1.45 | Thieno[3,2-b]thiophene in complex with T4 lysozyme L99A/M102Q |
| 3HU9 | 2009-11-03 | 1.46 | Nitrosobenzene in complex with T4 lysozyme L99A/M102Q |
| 5KI1 | 2017-04-12 | 1.46 | PSEUDO T4 LYSOZYME MUTANT - Y18F |
| 2RB2 | 2008-03-18 | 1.46 | 3-methylbenzylazide in complex with T4 lysozyme L99A |
| 5JGR | 2017-02-15 | 1.46 | Spin-Labeled T4 Lysozyme Construct K43V1 |
| 2RBP | 2008-03-18 | 1.47 | 2-(n-propylthio)ethanol in complex with T4 lysozyme L99A/M102Q |
| 5JWW | 2016-09-21 | 1.47 | T4 Lysozyme L99A/M102Q with 1-Hydro-2-ethyl-1,2-azaborine Bound |
| 5JGU | 2017-02-15 | 1.47 | Spin-Labeled T4 Lysozyme Construct R119V1 |
| 5KGR | 2017-02-15 | 1.47 | Spin-Labeled T4 Lysozyme Construct I9V1/V131V1 (30 days) |
| 4I7M | 2013-03-27 | 1.48 | T4 Lysozyme L99A/M102H with 2-allylphenol bound |
| 5KHZ | 2017-04-12 | 1.49 | PSEUDO T4 LYSOZYME |
| 4EKR | 2012-09-05 | 1.49 | T4 Lysozyme L99A/M102H with 2-Cyanophenol Bound |
| 5KIG | 2017-04-12 | 1.5 | PSEUDO T4 LYSOZYME MUTANT - Y88F |
| 4W52 | 2015-04-01 | 1.5 | T4 Lysozyme L99A with Benzene Bound |
| 5KIM | 2017-04-12 | 1.5 | PSEUDO T4 LYSOZYME MUTANT - Y88PHE-I |
| 3GUP | 2009-08-25 | 1.5 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--pyridine binding |
| 3K2R | 2010-10-13 | 1.5 | Crystal Structure of Spin Labeled T4 Lysozyme Mutant K65V1/R76V1 |
| 1P7S | 2003-10-07 | 1.5 | T4 LYSOZYME CORE REPACKING MUTANT V103I/TA |
| 3GUN | 2009-08-25 | 1.5 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--aniline binding |
| 5KI2 | 2017-04-12 | 1.5 | PSEUDO T4 LYSOZYME MUTANT - Y18PHE-METHYL |
| 4I7R | 2013-03-27 | 1.52 | T4 Lysozyme L99A/M102H with 2-(pyrazolo-1-yl) ethanol bound |
| 1PQM | 2003-10-07 | 1.52 | T4 Lysozyme Core Repacking Mutant V149I/T152V/TA |
| 4I7L | 2013-04-03 | 1.52 | T4 Lysozyme L99A/M102H with phenol bound |
| 5JGZ | 2017-02-15 | 1.53 | Spin-Labeled T4 Lysozyme Construct T151V1 |
| 5JGX | 2017-02-15 | 1.53 | Spin-Labeled T4 Lysozyme Construct V131V1 |
| 3FI5 | 2009-02-17 | 1.53 | Crystal Structure of T4 Lysozyme Mutant R96W |
| 5JGN | 2017-02-15 | 1.53 | Spin-Labeled T4 Lysozyme Construct I9V1 |
| 4EKQ | 2012-09-05 | 1.54 | T4 Lysozyme L99A/M102H with 4-Nitrophenol Bound |
| 1P6Y | 2003-10-07 | 1.54 | T4 LYSOZYME CORE REPACKING MUTANT M120Y/TA |
| 5KI8 | 2017-04-12 | 1.55 | PSEUDO T4 LYSOZYME MUTANT - Y88PHE-BR |
| 1XEP | 2005-05-31 | 1.55 | Catechol in complex with T4 lysozyme L99A/M102Q |
| 4I7T | 2013-03-27 | 1.55 | T4 Lysozyme L99A/M102H with 2-bromo-5-hydroxybenzaldehyde bound |
| 1P3N | 2003-10-07 | 1.55 | CORE REDESIGN BACK-REVERTANT I103V/CORE10 |
| 2OU9 | 2007-06-12 | 1.55 | Structure of Spin-labeled T4 Lysozyme Mutant T115R1/R119A |
| 5KII | 2017-04-12 | 1.56 | PSEUDO T4 LYSOZYME MUTANT - Y88PHE-METHYL |
| 4W53 | 2015-04-01 | 1.56 | T4 Lysozyme L99A with Toluene Bound |
| 2RBS | 2008-03-18 | 1.56 | (r)(+)-3-chloro-1-phenyl-1-propanol in complex with T4 lysozyme L99A/M102Q |
| 1PQI | 2003-10-07 | 1.57 | T4 LYSOZYME CORE REPACKING MUTANT I118L/CORE7/TA |
| 1P37 | 2003-10-07 | 1.57 | T4 LYSOZYME CORE REPACKING BACK-REVERTANT L102M/CORE10 |
| 4I7Q | 2013-03-27 | 1.58 | T4 Lysozyme L99A/M102H with 4-trifluoromethylimidazole bound |
| 4I7N | 2013-03-27 | 1.58 | T4 Lysozyme L99A/M102H with 1-phenyl-2-propyn-1-ol bound |
| 1P2L | 2003-10-07 | 1.58 | T4 Lysozyme Core Repacking Mutant V87I/TA |
| 1P2R | 2003-10-07 | 1.58 | T4 LYSOZYME CORE REPACKING MUTANT I78V/TA |
| 3HT6 | 2009-11-03 | 1.59 | 2-methylphenol in complex with T4 lysozyme L99A/M102Q |
| 3GUJ | 2009-08-25 | 1.6 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Benzene binding |
| 1ZUR | 2006-10-17 | 1.6 | Crystal structure of spin labeled T4 Lysozyme (V131R1F) |
| 3HT8 | 2009-11-03 | 1.6 | 5-chloro-2-methylphenol in complex with T4 lysozyme L99A/M102Q |
| 4I7P | 2013-03-27 | 1.6 | T4 Lysozyme L99A/M102H with 4-bromoimidazole bound |
| 5V88 | 2017-05-24 | 1.6 | Structure of DCN1 bound to NAcM-COV |
| 5G27 | 2016-11-23 | 1.61 | Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at Room Temperature |
| 1P64 | 2003-10-07 | 1.62 | T4 LYSOZYME CORE REPACKING MUTANT L133F/TA |
| 5KIO | 2017-04-12 | 1.63 | PSEUDO T4 LYSOZYME MUTANT - Y18PHE-I |
| 4W56 | 2015-04-01 | 1.63 | T4 Lysozyme L99A with sec-Butylbenzene Bound |
| 2RBQ | 2008-03-18 | 1.63 | 3-methylbenzylazide in complex with T4 L99A/M102Q |
| 5VNR | 2017-07-26 | 1.63 | X-ray strucutre of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature |
| 3CDT | 2009-02-17 | 1.63 | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme |
| 4EKS | 2012-09-05 | 1.64 | T4 Lysozyme L99A/M102H with Isoxazole Bound |
| 3C8Q | 2009-02-17 | 1.64 | Contribution of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme |
| 2RAZ | 2008-03-18 | 1.64 | 4-(methylthio)nitrobenzene in complex with T4 lysozyme L99A |
| 4W55 | 2015-04-01 | 1.64 | T4 Lysozyme L99A with n-Propylbenzene Bound |
| 4EKP | 2012-09-05 | 1.64 | T4 Lysozyme L99A/M102H with Nitrobenzene Bound |
| 119L | 1993-10-31 | 1.65 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1L58 | 1991-10-15 | 1.65 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 1PQO | 2003-10-07 | 1.65 | T4 Lysozyme Core Repacking Mutant L118I/TA |
| 1LPY | 2002-05-22 | 1.65 | Multiple Methionine Substitutions in T4 Lysozyme |
| 5V7F | 2018-06-20 | 1.65 | T4 lysozyme Y18Ymi |
| 3DMV | 2008-11-11 | 1.65 | Free of ligand binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 1PQD | 2003-10-07 | 1.65 | T4 LYSOZYME CORE REPACKING MUTANT CORE10/TA |
| 5JWS | 2016-09-21 | 1.65 | T4 Lysozyme L99A with 1-Hydro-2-ethyl-1,2-azaborine Bound |
| 5KI3 | 2017-04-12 | 1.65 | PSEUDO T4 LYSOZYME MUTANT - Y18PHE-BR |
| 219L | 1996-12-23 | 1.66 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 4I7J | 2013-03-27 | 1.67 | T4 Lysozyme L99A/M102H with benzene bound |
| 3C7Z | 2009-02-17 | 1.67 | T4 lysozyme mutant D89A/R96H at room temperature |
| 1P46 | 2003-10-07 | 1.67 | T4 lysozyme core repacking mutant M106I/TA |
| 4W57 | 2015-04-01 | 1.68 | T4 Lysozyme L99A with n-Butylbenzene Bound |
| 3CDQ | 2009-02-17 | 1.68 | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme |
| 3C82 | 2009-02-17 | 1.68 | Bacteriophage lysozyme T4 lysozyme mutant K85A/R96H |
| 3C8S | 2009-02-17 | 1.68 | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme |
| 4I7S | 2013-03-27 | 1.69 | T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound |
| 1L06 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 3DN8 | 2008-11-11 | 1.7 | Iodopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant (seleno version) |
| 1L33 | 1990-01-15 | 1.7 | CONTRIBUTIONS OF LEFT-HANDED HELICAL RESIDUES TO THE STRUCTURE AND STABILITY OF BACTERIOPHAGE T4 LYSOZYME |
| 130L | 1994-01-31 | 1.7 | STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT |
| 221L | 1994-01-31 | 1.7 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1KNI | 2001-12-28 | 1.7 | Stabilizing Disulfide Bridge Mutant of T4 Lysozyme |
| 1L44 | 1991-10-15 | 1.7 | CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY |
| 1L74 | 1991-10-15 | 1.7 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 173L | 1995-07-10 | 1.7 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 1L07 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1L22 | 1990-01-15 | 1.7 | CONTRIBUTIONS OF LEFT-HANDED HELICAL RESIDUES TO THE STRUCTURE AND STABILITY OF BACTERIOPHAGE T4 LYSOZYME |
| 1L30 | 1990-01-15 | 1.7 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 1L47 | 1991-10-15 | 1.7 | CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY |
| 1L26 | 1990-01-15 | 1.7 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 241L | 1998-03-18 | 1.7 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 2A4T | 2006-06-13 | 1.7 | Crystal structure of spin labeled T4 Lysozyme (V131R7) |
| 1L09 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 211L | 1996-12-23 | 1.7 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 5JWU | 2016-09-21 | 1.7 | T4 Lysozyme L99A/M102Q with 1,2-Dihydro-1,2-azaborine Bound |
| 217L | 1993-10-31 | 1.7 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 138L | 1994-01-31 | 1.7 | RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING |
| 1L46 | 1991-10-15 | 1.7 | CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY |
| 3DNA | 2008-11-11 | 1.7 | Iodobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant (seleno version) |
| 1L36 | 1991-10-15 | 1.7 | TOWARD A SIMPLIFICATION OF THE PROTEIN FOLDING PROBLEM: A STABILIZING POLYALANINE ALPHA-HELIX ENGINEERED IN T4 LYSOZYME |
| 1L04 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1L65 | 1991-10-15 | 1.7 | TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES |
| 1L29 | 1990-01-15 | 1.7 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 110L | 1993-10-31 | 1.7 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 1G0M | 2001-05-23 | 1.7 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152I |
| 1L01 | 1988-04-16 | 1.7 | STRUCTURAL STUDIES OF MUTANTS OF THE LYSOZYME OF BACTERIOPHAGE T4. THE TEMPERATURE-SENSITIVE MUTANT PROTEIN THR157 (RIGHT ARROW) ILE |
| 1L02 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1LWG | 2003-05-20 | 1.7 | Multiple Methionine Substitutions are Tolerated in T4 Lysozyme and have Coupled Effects on Folding and Stability |
| 237L | 1998-03-18 | 1.7 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 3LZM | 1990-01-15 | 1.7 | STRUCTURAL STUDIES OF MUTANTS OF T4 LYSOZYME THAT ALTER HYDROPHOBIC STABILIZATION |
| 2LZM | 1986-10-24 | 1.7 | STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME REFINED AT 1.7 ANGSTROMS RESOLUTION |
| 1L92 | 1993-10-31 | 1.7 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 1L12 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1L15 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1L24 | 1990-01-15 | 1.7 | ENHANCED PROTEIN THERMOSTABILITY FROM SITE-DIRECTED MUTATIONS THAT DECREASE THE ENTROPY OF UNFOLDING |
| 161L | 1994-08-31 | 1.7 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1L17 | 1990-01-15 | 1.7 | HYDROPHOBIC STABILIZATION IN T4 LYSOZYME DETERMINED DIRECTLY BY MULTIPLE SUBSTITUTIONS OF ILE 3 |
| 1L52 | 1991-10-15 | 1.7 | STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME |
| 1L60 | 1991-10-15 | 1.7 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 1L45 | 1991-10-15 | 1.7 | CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY |
| 4LZM | 1992-07-15 | 1.7 | COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS |
| 2F47 | 2006-04-25 | 1.7 | Xray crystal structure of T4 lysozyme mutant L20/R63A liganded to methylguanidinium |
| 1L23 | 1990-01-15 | 1.7 | ENHANCED PROTEIN THERMOSTABILITY FROM SITE-DIRECTED MUTATIONS THAT DECREASE THE ENTROPY OF UNFOLDING |
| 129L | 1994-01-31 | 1.7 | STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT |
| 1G07 | 2001-05-23 | 1.7 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149C |
| 131L | 1994-01-31 | 1.7 | STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT |
| 1L11 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1L48 | 1991-10-15 | 1.7 | STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME |
| 1L62 | 1991-10-15 | 1.7 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 2RB1 | 2008-06-03 | 1.7 | 2-ethoxyphenol in complex with T4 lysozyme L99A |
| 1L18 | 1990-01-15 | 1.7 | HYDROPHOBIC STABILIZATION IN T4 LYSOZYME DETERMINED DIRECTLY BY MULTIPLE SUBSTITUTIONS OF ILE 3 |
| 1L05 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1L08 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 1LYH | 1993-10-31 | 1.7 | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 |
| 1L10 | 1988-04-16 | 1.7 | STRUCTURAL STUDIES OF MUTANTS OF THE LYSOZYME OF BACTERIOPHAGE T4. THE TEMPERATURE-SENSITIVE MUTANT PROTEIN THR157 (RIGHT ARROW) ILE |
| 1L32 | 1990-01-15 | 1.7 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 244L | 1998-03-18 | 1.7 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1L19 | 1990-01-15 | 1.7 | ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES |
| 128L | 1993-10-31 | 1.7 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1L03 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 3HT7 | 2009-11-03 | 1.7 | 2-ethylphenol in complex with T4 lysozyme L99A/M102Q |
| 1L83 | 1993-10-31 | 1.7 | A CAVITY-CONTAINING MUTANT OF T4 LYSOZYME IS STABILIZED BY BURIED BENZENE |
| 1L14 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 139L | 1994-01-31 | 1.7 | RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING |
| 1L66 | 1991-10-15 | 1.7 | TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES |
| 3CDR | 2009-02-17 | 1.7 | R96Q Mutant of wildtype phage T4 lysozyme at 298 K |
| 1L16 | 1988-04-16 | 1.7 | STRUCTURAL ANALYSIS OF THE TEMPERATURE-SENSITIVE MUTANT OF BACTERIOPHAGE T4 LYSOZYME, GLYCINE 156 (RIGHT ARROW) ASPARTIC ACID |
| 1L68 | 1991-10-15 | 1.7 | TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES |
| 1ZYT | 2006-08-15 | 1.7 | Crystal structure of spin labeled T4 Lysozyme (A82R1) |
| 1L13 | 1988-04-16 | 1.7 | CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME |
| 4I7K | 2013-03-27 | 1.72 | T4 Lysozyme L99A/M102H with toluene bound |
| 5JGV | 2017-02-15 | 1.73 | Spin-Labeled T4 Lysozyme Construct A73V1 |
| 4I7O | 2013-03-27 | 1.73 | T4 Lysozyme L99A/M102H with 2-amino-5-chlorothiazole bound |
| 232L | 1998-01-14 | 1.73 | T4 LYSOZYME MUTANT M120K |
| 3CDV | 2009-02-17 | 1.73 | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme |
| 102L | 1993-10-31 | 1.74 | HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME |
| 4EPI | 2012-06-20 | 1.74 | The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds |
| 166L | 1994-08-31 | 1.75 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1QUD | 1999-07-08 | 1.75 | L99G MUTANT OF T4 LYSOZYME |
| 243L | 1998-03-18 | 1.75 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 5I14 | 2016-02-17 | 1.75 | Truncated and mutated T4 lysozyme |
| 1KW5 | 2003-06-03 | 1.75 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 1L90 | 1993-10-31 | 1.75 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 2CUU | 2006-08-15 | 1.75 | Crystal structure of spin labeled T4 Lysozyme (V131R1) |
| 1DYB | 1993-10-31 | 1.75 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 1L41 | 1991-10-15 | 1.75 | CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS |
| 180L | 1996-04-03 | 1.75 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 240L | 1998-03-18 | 1.75 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1L63 | 1991-10-15 | 1.75 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 206L | 1996-08-17 | 1.75 | PHAGE T4 LYSOZYME |
| 247L | 1998-03-18 | 1.75 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1L59 | 1991-10-15 | 1.75 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 165L | 1994-08-31 | 1.75 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 212L | 1996-12-23 | 1.76 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 3C7W | 2009-02-17 | 1.77 | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme |
| 6FW2 | 2018-10-31 | 1.78 | Crystal Structure of human mARC1 |
| 4W54 | 2015-04-01 | 1.79 | T4 Lysozyme L99A with Ethylbenzene Bound |
| 260L | 2000-09-11 | 1.8 | AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME |
| 3L2X | 2011-01-05 | 1.8 | Crystal Structure of Spin Labeled T4 Lysozyme Mutant 115-119RX |
| 1L35 | 1990-01-15 | 1.8 | STRUCTURE OF A THERMOSTABLE DISULFIDE-BRIDGE MUTANT OF PHAGE T4 LYSOZYME SHOWS THAT AN ENGINEERED CROSSLINK IN A FLEXIBLE REGION DOES NOT INCREASE THE RIGIDITY OF THE FOLDED PROTEIN |
| 3DN6 | 2008-11-11 | 1.8 | 1,3,5-trifluoro-2,4,6-trichlorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 256L | 1998-05-27 | 1.8 | BACTERIOPHAGE T4 LYSOZYME |
| 164L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1L61 | 1991-10-15 | 1.8 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 3C8R | 2009-02-17 | 1.8 | Contributions of all 20 amino acids at site 96 to stability and structure of T4 lysozyme |
| 1G0P | 2001-05-23 | 1.8 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149G |
| 1G0L | 2001-05-23 | 1.8 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152V |
| 2O79 | 2007-04-10 | 1.8 | T4 lysozyme with C-terminal extension |
| 1L94 | 1993-10-31 | 1.8 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 258L | 2000-09-11 | 1.8 | AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME |
| 1L80 | 1993-04-15 | 1.8 | DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME |
| 185L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 1ZWN | 2006-10-17 | 1.8 | Crystal structure of spin labeled T4 Lysozyme (V131R1B) |
| 1G0Q | 2001-05-23 | 1.8 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149I |
| 250L | 1998-03-18 | 1.8 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 183L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 1DYE | 1993-10-31 | 1.8 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 1QT5 | 1999-07-08 | 1.8 | D20E MUTANT STRUCTURE OF T4 LYSOZYME |
| 1LYJ | 1993-10-31 | 1.8 | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 |
| 6LZM | 1992-07-15 | 1.8 | COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS |
| 1L38 | 1991-10-15 | 1.8 | CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS |
| 108L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 159L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 5LZM | 1992-07-15 | 1.8 | COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS |
| 242L | 1998-03-18 | 1.8 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 4W58 | 2015-04-01 | 1.8 | T4 Lysozyme L99A with n-Pentylbenzene Bound |
| 2NTH | 2007-06-12 | 1.8 | Structure of Spin-labeled T4 Lysozyme Mutant L118R1 |
| 3DN2 | 2008-11-11 | 1.8 | Bromopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 7LZM | 1992-07-15 | 1.8 | COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS |
| 1L98 | 1993-10-31 | 1.8 | PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES |
| 3HU8 | 2009-11-03 | 1.8 | 2-ethoxyphenol in complex with T4 lysozyme L99A/M102Q |
| 123L | 1993-10-31 | 1.8 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1LYE | 1993-10-31 | 1.8 | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 |
| 181L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 1T8G | 2004-10-19 | 1.8 | Crystal structure of phage T4 lysozyme mutant L32A/L33A/T34A/C54T/C97A/E108V |
| 1LYF | 1993-10-31 | 1.8 | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 |
| 3DMX | 2009-01-27 | 1.8 | Benzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 186L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 107L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 120L | 1993-10-31 | 1.8 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 126L | 1993-10-31 | 1.8 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1P56 | 2004-05-04 | 1.8 | Duplication-extension of Helix A of T4 lysozyme |
| 160L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1L43 | 1991-10-15 | 1.8 | CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY |
| 2HUL | 2006-10-17 | 1.8 | Crystal structure of T4 Lysozyme S44C synthetic dimer |
| 115L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 184L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 1QT7 | 1999-07-08 | 1.8 | E11N Mutant of T4 Lysozyme |
| 1L56 | 1991-10-15 | 1.8 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 158L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1NHB | 1995-07-10 | 1.8 | Specificity of ligand binding in a buried non-polar cavity of t4 lysozyme: linkage of dynamics and structural plasticity |
| 3DN4 | 2008-11-11 | 1.8 | Iodobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 245L | 1998-03-18 | 1.8 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 226L | 1998-03-18 | 1.8 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 3DN3 | 2008-11-11 | 1.8 | Iodopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 156L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 122L | 1993-10-31 | 1.8 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1L91 | 1993-10-31 | 1.8 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 114L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 1QSB | 1999-07-07 | 1.8 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 182L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 1CVK | 1999-11-10 | 1.8 | T4 LYSOZYME MUTANT L118A |
| 255L | 1998-01-28 | 1.8 | HYDROLASE |
| 1G1W | 2001-05-09 | 1.8 | T4 LYSOZYME MUTANT C54T/C97A/Q105M |
| 1G0J | 2001-05-23 | 1.8 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152S |
| 188L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 112L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 111L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 2F32 | 2006-04-25 | 1.8 | Xray crystal structure of lysozyme mutant L20/R63A liganded to ethylguanidinium |
| 2OU8 | 2007-06-12 | 1.8 | Structure of Spin-labeled T4 Lysozyme Mutant T115R1 at Room Temperature |
| 1L86 | 1993-10-31 | 1.8 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 2RAY | 2008-03-18 | 1.8 | beta-chlorophenetole in complex with T4 lysozyme L99A |
| 1L87 | 1993-10-31 | 1.8 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 163L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 3HWL | 2009-12-08 | 1.8 | Crystal Structure of T4 lysozyme with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 131 |
| 1L27 | 1990-01-15 | 1.8 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 229L | 1998-03-18 | 1.8 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 162L | 1994-08-31 | 1.8 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1L31 | 1990-01-15 | 1.8 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 187L | 1995-07-10 | 1.8 | SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY |
| 1L25 | 1990-01-15 | 1.8 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 113L | 1993-10-31 | 1.8 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 1LYG | 1993-10-31 | 1.8 | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 |
| 3DN0 | 2008-11-11 | 1.8 | Pentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 1LLH | 2002-05-15 | 1.8 | ARE CARBOXY TERMINII OF HELICES CODED BY THE LOCAL SEQUENCE OR BY TERTIARY STRUCTURE CONTACTS |
| 1CV3 | 1999-08-24 | 1.8 | T4 LYSOZYME MUTANT L121M |
| 1L93 | 1993-10-31 | 1.8 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 3G3X | 2009-05-05 | 1.8 | Crystal structure of spin labeled T4 Lysozyme (T151R1) at 100 K |
| 1L49 | 1991-10-15 | 1.8 | STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME |
| 1C69 | 2000-10-04 | 1.8 | T4 LYSOZYME MUTANT C54T/C97A/L133A IN THE PRESENCE OF 8 ATM ARGON |
| 118L | 1993-10-31 | 1.8 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 239L | 1998-03-18 | 1.8 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 238L | 1998-03-18 | 1.8 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1L42 | 1991-10-15 | 1.8 | CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY |
| 3DN1 | 2008-11-11 | 1.8 | Chloropentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 246L | 1998-03-18 | 1.8 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 3HTB | 2009-11-03 | 1.81 | 2-propylphenol in complex with T4 lysozyme L99A/M102Q |
| 2OTY | 2007-08-07 | 1.83 | 1,2-dichlorobenzene in complex with T4 Lysozyme L99A |
| 3C83 | 2009-02-17 | 1.84 | Bacteriophage T4 lysozyme mutant D89A in wildtype background at room temperature |
| 2RB0 | 2008-03-18 | 1.84 | 2,6-difluorobenzylbromide complex with T4 lysozyme L99A |
| 146L | 1994-01-31 | 1.85 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 109L | 1993-10-31 | 1.85 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 1L21 | 1990-01-15 | 1.85 | CONTRIBUTIONS OF LEFT-HANDED HELICAL RESIDUES TO THE STRUCTURE AND STABILITY OF BACTERIOPHAGE T4 LYSOZYME |
| 3GUK | 2009-08-25 | 1.85 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Toluene binding |
| 157L | 1994-08-31 | 1.85 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1L53 | 1991-10-15 | 1.85 | STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME |
| 1QT3 | 1999-07-08 | 1.85 | T26D MUTANT OF T4 LYSOZYME |
| 1QUH | 1999-07-08 | 1.85 | L99G/E108V MUTANT OF T4 LYSOZYME |
| 125L | 1993-10-31 | 1.85 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 3C81 | 2009-02-17 | 1.85 | Mutant K85A of T4 lysozyme in wildtype background at room temperature |
| 1L72 | 1991-10-15 | 1.85 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 1G0K | 2001-05-23 | 1.85 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152C |
| 199L | 1996-03-08 | 1.85 | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN 'SIZE-SWITCH' CORE-REPACKING VARIANTS OF T4 LYSOZYME |
| 1L73 | 1991-10-15 | 1.85 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 127L | 1993-10-31 | 1.85 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 137L | 1994-07-31 | 1.85 | STRUCTURAL BASIS OF AMINO ACID ALPHA HELIX PROPENSITY |
| 1L39 | 1991-10-15 | 1.85 | CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS |
| 3HTF | 2009-11-03 | 1.85 | 4-chloro-1h-pyrazole in complex with T4 lysozyme L99A/M102Q |
| 1L88 | 1993-10-31 | 1.85 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 224L | 1994-01-31 | 1.85 | THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME |
| 1QS9 | 1999-07-02 | 1.85 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 1L71 | 1991-10-15 | 1.85 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 1L20 | 1990-01-15 | 1.85 | ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES |
| 1L37 | 1991-10-15 | 1.85 | CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS |
| 1L50 | 1991-10-15 | 1.85 | STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME |
| 1L40 | 1991-10-15 | 1.85 | CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS |
| 1G06 | 2001-05-23 | 1.85 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149S |
| 220L | 1998-03-18 | 1.85 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 155L | 1994-08-31 | 1.85 | CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND |
| 1LGW | 2002-05-08 | 1.85 | T4 Lysozyme Mutant L99A/M102Q Bound by 2-fluoroaniline |
| 1CU2 | 1999-11-10 | 1.85 | T4 LYSOZYME MUTANT L84M |
| 1EPY | 2000-04-12 | 1.85 | T4 LYSOZYME MUTANT, T21H/C54T/C97A/Q141H/T142H |
| 1LI3 | 2002-05-08 | 1.85 | T4 lysozyme mutant L99A/M102Q bound by 3-chlorophenol |
| 1CV5 | 1999-11-10 | 1.87 | T4 LYSOZYME MUTANT L133M |
| 3CDO | 2009-02-17 | 1.87 | Bacteriophage T4 lysozyme mutant R96V in wildtype background at low temperature |
| 1KW7 | 2003-06-03 | 1.89 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 210L | 1996-12-23 | 1.89 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 1CUP | 1999-11-10 | 1.89 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 1D2W | 1999-10-08 | 1.89 | N-TERMINAL DOMAIN CORE METHIONINE MUTATION |
| 214L | 1996-12-23 | 1.89 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 230L | 1998-01-14 | 1.9 | T4 LYSOZYME MUTANT M6L |
| 1L89 | 1993-10-31 | 1.9 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 1L75 | 1991-10-15 | 1.9 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 1L51 | 1991-10-15 | 1.9 | STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME |
| 233L | 1998-01-14 | 1.9 | T4 LYSOZYME MUTANT M120L |
| 1L28 | 1990-01-15 | 1.9 | REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY |
| 1DYA | 1993-10-31 | 1.9 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 1QTH | 1999-07-22 | 1.9 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 228L | 1998-03-18 | 1.9 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 1L70 | 1991-10-15 | 1.9 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 1L67 | 1991-10-15 | 1.9 | TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES |
| 1C6L | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A/F153A IN THE PRESENCE OF 8 ATM ARGON |
| 1QT6 | 1999-07-08 | 1.9 | E11H Mutant of T4 Lysozyme |
| 2O4W | 2007-04-10 | 1.9 | T4 lysozyme circular permutant |
| 257L | 2000-09-11 | 1.9 | AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME |
| 1OWY | 2004-04-13 | 1.9 | T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Propyl-Aniline |
| 1LGX | 2002-05-08 | 1.9 | T4 Lysozyme Mutant L99A/M102Q Bound by 3,5-difluoroaniline |
| 234L | 1998-01-14 | 1.9 | T4 LYSOZYME MUTANT M106L |
| 1QSQ | 1999-06-29 | 1.9 | CAVITY CREATING MUTATION |
| 1QTB | 1999-07-02 | 1.9 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 1G1V | 2001-05-09 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/I58T |
| 3L64 | 2010-01-19 | 1.9 | T4 Lysozyme S44E/WT* |
| 4WTV | 2015-07-15 | 1.9 | Crystal structure of the phosphatidylinositol 4-kinase IIbeta |
| 1OWZ | 2004-04-13 | 1.9 | T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 4-FluoroPhenEthyl Alcohol |
| 1L54 | 1991-10-15 | 1.9 | THE STRUCTURAL AND THERMODYNAMIC CONSEQUENCES OF BURYING A CHARGED RESIDUE WITHIN THE HYDROPHOBIC CORE OF T4 LYSOZYME |
| 1L57 | 1991-10-15 | 1.9 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 1L55 | 1991-10-15 | 1.9 | ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME |
| 1L64 | 1991-10-15 | 1.9 | TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES |
| 222L | 1998-03-18 | 1.9 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 148L | 1994-04-30 | 1.9 | A COVALENT ENZYME-SUBSTRATE INTERMEDIATE WITH SACCHARIDE DISTORTION IN A MUTANT T4 LYSOZYME |
| 1L76 | 1991-10-15 | 1.9 | TOLERANCE OF T4 LYSOZYME TO PROLINE SUBSTITUTIONS WITHIN THE LONG INTERDOMAIN ALPHA-HELIX ILLUSTRATES THE ADAPTABILITY OF PROTEINS TO POTENTIALLY DESTABILIZING LESIONS |
| 1QT8 | 1999-07-08 | 1.9 | T26H Mutant of T4 Lysozyme |
| 103L | 1993-10-31 | 1.9 | HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME |
| 236L | 1998-03-18 | 1.9 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1L79 | 1993-04-15 | 1.9 | DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME |
| 1C6K | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 8 ATM XENON |
| 1L34 | 1990-01-15 | 1.9 | HIGH-RESOLUTION STRUCTURE OF THE TEMPERATURE-SENSITIVE MUTANT OF PHAGE LYSOZYME, ARG 96 (RIGHT ARROW) HIS |
| 1QUO | 1999-07-08 | 1.9 | L99A/E108V MUTANT OF T4 LYSOZYME |
| 254L | 1998-01-28 | 1.9 | LYSOZYME |
| 1PQJ | 2003-10-07 | 1.9 | T4 LYSOZYME CORE REPACKING MUTANT A111V/CORE10/TA |
| 248L | 1998-03-18 | 1.9 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1C6J | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 8 ATM KRYPTON |
| 1B6I | 2000-01-12 | 1.9 | T4 LYSOZYME MUTANT WITH CYS 54 REPLACED BY THR, CYS 97 REPLACED BY ALA, THR 21 REPLACED BY CYS AND LYS 124 REPLACED BY CYS (C54T,C97A,T21C,K124C) |
| 1C6H | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 4 ATM XENON |
| 1CV4 | 1999-11-10 | 1.9 | T4 LYSOZYME MUTANT L118M |
| 192L | 1995-09-15 | 1.9 | A HELIX INITIATION SIGNAL IN T4 LYSOZYME IDENTIFIED BY POLYALANINE MUTAGENESIS |
| 195L | 1996-03-08 | 1.9 | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN 'SIZE-SWITCH' CORE-REPACKING VARIANTS OF T4 LYSOZYME |
| 249L | 1998-03-18 | 1.9 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1C6I | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 8 ATM ARGON |
| 1C6E | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 2 ATM XENON |
| 1C6P | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A IN THE PRESENCE OF 8 ATM ARGON |
| 1LGU | 2002-05-08 | 1.9 | T4 Lysozyme Mutant L99A/M102Q |
| 1JTM | 2002-03-20 | 1.9 | Alternative Structures of a Sequence Extended T4 Lysozyme Show that the Highly Conserved Beta-Sheet has Weak Intrinsic Folding Propensity |
| 225L | 1998-03-18 | 1.9 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 1L84 | 1993-10-31 | 1.9 | A CAVITY-CONTAINING MUTANT OF T4 LYSOZYME IS STABILIZED BY BURIED BENZENE |
| 1CV6 | 1999-11-10 | 1.9 | T4 LYSOZYME MUTANT V149M |
| 1C6Q | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A IN THE PRESENCE OF 8 ATM KRYPTON |
| 1G0G | 2001-05-23 | 1.9 | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152A |
| 1I6S | 2001-05-09 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/N101A |
| 1L00 | 1993-10-31 | 1.9 | PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES |
| 235L | 1998-03-18 | 1.9 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1C6G | 2000-10-04 | 1.9 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 4 ATM KRYPTON |
| 172L | 1995-07-10 | 1.9 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 223L | 1998-03-18 | 1.9 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 1DYF | 1993-10-31 | 1.9 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 1L69 | 1991-10-15 | 1.9 | MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY |
| 1QUG | 1999-07-08 | 1.9 | E108V MUTANT OF T4 LYSOZYME |
| 1D9W | 1999-11-17 | 1.91 | BACTERIOPHAGE T4 LYSOZYME MUTANT |
| 259L | 1999-04-12 | 1.92 | AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME |
| 2OU0 | 2007-08-07 | 1.94 | 1-methylpyrrole in complex with T4 Lysozyme L99A |
| 1CX7 | 1999-11-10 | 1.94 | T4 LYSOZYME METHIONINE CORE MUTANT |
| 1OVH | 2004-04-06 | 1.95 | T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Chloro-6-Methyl-Aniline |
| 3C7Y | 2009-02-17 | 1.95 | Mutant R96A OF T4 lysozyme in wildtype background at 298K |
| 191L | 1995-09-15 | 1.95 | A HELIX INITIATION SIGNAL IN T4 LYSOZYME IDENTIFIED BY POLYALANINE MUTAGENESIS |
| 200L | 1996-03-08 | 1.95 | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN 'SIZE-SWITCH' CORE-REPACKING VARIANTS OF T4 LYSOZYME |
| 1L99 | 1993-10-31 | 1.95 | PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES |
| 215L | 1996-12-23 | 1.96 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 6IIH | 2019-08-14 | 1.96 | crystal structure of mitochondrial calcium uptake 2(MICU2) |
| 1KY0 | 2003-06-03 | 1.97 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 1D3J | 1999-10-08 | 1.97 | N-TERMINAL DOMAIN CORE METHIONINE MUTATION |
| 1L0J | 2003-06-03 | 1.98 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 3C80 | 2009-02-17 | 1.99 | T4 Lysozyme mutant R96Y at room temperature |
| 2HUK | 2006-10-17 | 2.0 | Crystal structure of T4 Lysozyme V131C synthetic dimer |
| 1C65 | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/L121A IN THE PRESENCE OF 8 ATM XENON |
| 143L | 1994-01-31 | 2.0 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 1C64 | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/L121A IN THE PRESENCE OF 8 ATM KRYPTON |
| 1L95 | 1993-10-31 | 2.0 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 1D3N | 1999-09-30 | 2.0 | METHIONINE CORE MUTATION |
| 1L96 | 1993-10-31 | 2.0 | STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO |
| 1L81 | 1993-04-15 | 2.0 | DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME |
| 1LYD | 1990-04-15 | 2.0 | CRYSTAL STRUCTURE OF T4-LYSOZYME GENERATED FROM SYNTHETIC CODING DNA EXPRESSED IN ESCHERICHIA COLI |
| 152L | 1994-05-31 | 2.0 | CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME |
| 1C60 | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/F153A IN THE PRESENCE OF 8 ATM ARGON |
| 1C6T | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A IN THE PRESENCE OF 8 ATM XENON |
| 4YX7 | 2015-06-03 | 2.0 | Complex of SpaO(SPOA1,2) and OrgB(APAR)::T4lysozyme fusion protein |
| 1LYI | 1993-10-31 | 2.0 | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 |
| 1L97 | 1993-10-31 | 2.0 | STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO |
| 1QTZ | 1999-07-08 | 2.0 | D20C MUTANT OF T4 LYSOZYME |
| 1C6C | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 16 ATM ARGON |
| 2L78 | 1993-04-15 | 2.0 | DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME |
| 1C6D | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 16 ATM KRYPTON |
| 1OVJ | 2004-04-06 | 2.0 | T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 3-Fluoro-2-Methyl_Aniline |
| 3DMZ | 2008-11-11 | 2.0 | Hexafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant |
| 1L85 | 1993-10-31 | 2.0 | SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES |
| 142L | 1994-01-31 | 2.0 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 1PQK | 2003-10-07 | 2.0 | Repacking of the Core of T4 Lysozyme by Automated Design |
| 147L | 1994-01-31 | 2.0 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 145L | 1994-01-31 | 2.0 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 190L | 1995-09-15 | 2.0 | A HELIX INITIATION SIGNAL IN T4 LYSOZYME IDENTIFIED BY POLYALANINE MUTAGENESIS |
| 1LI2 | 2002-05-08 | 2.0 | T4 Lysozyme Mutant L99A/M102Q Bound by Phenol |
| 1T8A | 2004-08-17 | 2.0 | USE OF SEQUENCE DUPLICATION TO ENGINEER A LIGAND-TRIGGERED LONG-DISTANCE MOLECULAR SWITCH IN T4 Lysozyme |
| 1C6F | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/L99A IN THE PRESENCE OF 32 ATM ARGON |
| 253L | 1998-01-28 | 2.0 | LYSOZYME |
| 5V83 | 2017-05-24 | 2.0 | Structure of DCN1 bound to NAcM-HIT |
| 227L | 1998-03-18 | 2.0 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 201L | 1994-01-31 | 2.0 | HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME |
| 1C63 | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/L121A IN THE PRESENCE OF 8 ATM ARGON |
| 1LI6 | 2002-05-08 | 2.0 | T4 lysozyme mutant L99A/M102Q bound by 5-methylpyrrole |
| 141L | 1994-01-31 | 2.0 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 1OV7 | 2004-04-06 | 2.0 | T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 2-Allyl-6-Methyl-Phenol |
| 1C61 | 2000-10-04 | 2.0 | T4 LYSOZYME MUTANT C54T/C97A/F153A IN THE PRESENCE OF 8 ATM KRYPTON |
| 198L | 1996-03-08 | 2.0 | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN 'SIZE-SWITCH' CORE-REPACKING VARIANTS OF T4 LYSOZYME |
| 1TLA | 1993-07-15 | 2.0 | HYDROPHOBIC CORE REPACKING AND AROMATIC-AROMATIC INTERACTION IN THE THERMOSTABLE MUTANT OF T4 LYSOZYME SER 117 (RIGHT ARROW) PHE |
| 2OE9 | 2007-01-30 | 2.01 | High-pressure structure of pseudo-WT T4 Lysozyme |
| 1CX6 | 1999-12-15 | 2.01 | T4 LYSOZYME SUBSTITUTED WITH SELENOMETHIONINE |
| 1T6H | 2004-10-26 | 2.01 | Crystal Structure T4 Lysozyme incorporating an unnatural amino acid p-iodo-L-phenylalanine at position 153 |
| 2OEA | 2007-01-30 | 2.01 | High-pressure structure of pseudo-WT T4 Lysozyme |
| 3HT9 | 2009-11-03 | 2.02 | 2-methoxyphenol in complex with T4 lysozyme L99A/M102Q |
| 1L0K | 2003-06-03 | 2.02 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 1CU5 | 1999-11-10 | 2.05 | T4 LYSOZYME MUTANT L91M |
| 1L77 | 1993-04-15 | 2.05 | DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME |
| 1KY1 | 2003-06-03 | 2.05 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 218L | 1996-12-23 | 2.05 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 1CUQ | 1999-11-10 | 2.05 | T4 LYSOZYME MUTANT V103M |
| 1D3F | 1999-10-08 | 2.05 | N-TERMINAL DOMAIN CORE METHIONINE MUTATION |
| 1D2Y | 1999-10-08 | 2.06 | N-TERMINAL DOMAIN CORE METHIONINE MUTATION |
| 2OTZ | 2007-08-07 | 2.07 | N-methylaniline in complex with T4 Lysozyme L99A |
| 3GUL | 2009-08-25 | 2.07 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--ethylbenzene binding |
| 1L82 | 1993-04-15 | 2.1 | DESIGN AND STRUCTURAL ANALYSIS OF ALTERNATIVE HYDROPHOBIC CORE PACKING ARRANGEMENTS IN BACTERIOPHAGE T4 LYSOZYME |
| 205L | 1994-01-31 | 2.1 | HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME |
| 2B72 | 2005-11-08 | 2.1 | T4 Lysozyme mutant L99A at 100 MPa |
| 1C6A | 2000-10-04 | 2.1 | T4 LYSOZYME MUTANT C54T/C97A/L133A IN THE PRESENCE OF 8 ATM KRYPTON |
| 1CTW | 1999-11-10 | 2.1 | T4 LYSOZYME MUTANT I78A |
| 1C66 | 2000-10-04 | 2.1 | T4 LYSOZYME MUTANT C54T/C97A/L121A/L133A IN THE PRESENCE OF 8 ATM ARGON |
| 144L | 1994-01-31 | 2.1 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 2Q9E | 2007-06-26 | 2.1 | Structure of spin-labeled T4 lysozyme mutant S44R1 |
| 2B6T | 2005-11-08 | 2.1 | T4 Lysozyme mutant L99A at 200 MPa |
| 140L | 1994-01-31 | 2.1 | ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME |
| 1CU6 | 1999-11-17 | 2.1 | T4 LYSOZYME MUTANT L91A |
| 1LWK | 2003-05-20 | 2.1 | Multiple Methionine Substitutions are Tolerated in T4 Lysozyme and have Coupled Effects on Folding and Stability |
| 252L | 1998-03-18 | 2.1 | GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS |
| 2OE4 | 2007-01-30 | 2.1 | High Pressure Psuedo Wild Type T4 Lysozyme |
| 2OE7 | 2007-01-30 | 2.1 | High-Pressure T4 Lysozyme |
| 2B75 | 2005-11-08 | 2.1 | T4 Lysozyme mutant L99A at 150 MPa |
| 1DYG | 1993-10-31 | 2.1 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 1DYC | 1993-10-31 | 2.1 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 1C6M | 2000-10-04 | 2.1 | T4 LYSOZYME MUTANT C54T/C97A/L99A/F153A IN THE PRESENCE OF 8 ATM KRYPTON |
| 216L | 1994-07-31 | 2.1 | STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME |
| 1OVK | 2004-04-06 | 2.1 | T4 Lysozyme Cavity Mutant L99A/M102Q Bound with N-Allyl-Aniline |
| 1QT4 | 1999-07-08 | 2.1 | T26Q MUTANT OF T4 LYSOZYME |
| 3G3V | 2009-05-05 | 2.1 | Crystal structure of spin labeled T4 Lysozyme (V131R1) at 291 K |
| 175L | 1995-07-10 | 2.1 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 197L | 1996-03-08 | 2.1 | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN 'SIZE-SWITCH' CORE-REPACKING VARIANTS OF T4 LYSOZYME |
| 1OV5 | 2004-04-06 | 2.1 | T4 Lysozyme Cavity Mutant L99a/M102Q Bound With 2-Allylphenol |
| 1CV1 | 1999-11-10 | 2.1 | T4 LYSOZYME MUTANT V111M |
| 2B74 | 2005-11-08 | 2.1 | T4 Lysozyme mutant L99A at 100 MPa |
| 1DYD | 1993-10-31 | 2.1 | DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME |
| 2B6X | 2005-11-08 | 2.11 | T4 Lysozyme mutant L99A at 200 MPa |
| 1D3M | 1999-09-30 | 2.12 | METHIONINE CORE MUTATION |
| 1CV0 | 1999-11-10 | 2.12 | T4 LYSOZYME MUTANT F104M |
| 4S0W | 2015-02-04 | 2.12 | Wild type T4 lysozyme structure |
| 1CU3 | 1999-11-10 | 2.12 | T4 LYSOZYME MUTANT V87M |
| 213L | 1996-12-23 | 2.13 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 1SSW | 2004-10-19 | 2.13 | Crystal structure of phage T4 lysozyme mutant Y24A/Y25A/T26A/I27A/C54T/C97A |
| 1T8F | 2004-10-19 | 2.15 | Crystal structure of phage T4 lysozyme mutant R14A/K16A/I17A/K19A/T21A/E22A/C54T/C97A |
| 2B73 | 2005-11-08 | 2.15 | T4 Lysozyme mutant L99A at 100 MPa |
| 1KS3 | 2003-06-03 | 2.16 | METHIONINE CORE MUTANT OF T4 LYSOZYME |
| 3GUO | 2009-08-25 | 2.16 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--phenol binding |
| 5X93 | 2017-08-16 | 2.2 | Human endothelin receptor type-B in complex with antagonist K-8794 |
| 1C67 | 2000-10-04 | 2.2 | T4 LYSOZYME MUTANT C54T/C97A/L121A/L133A IN THE PRESENCE OF 8 ATM KRYPTON |
| 1C6N | 2000-10-04 | 2.2 | T4 LYSOZYME MUTANT C54T/C97A/L99A/F153A IN THE PRESENCE OF 8 ATM XENON |
| 167L | 1995-07-10 | 2.2 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 150L | 1994-04-30 | 2.2 | CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME |
| 1C6B | 2000-10-04 | 2.2 | T4 LYSOZYME MUTANT C54T/C97A/L133A IN THE PRESENCE OF 8 ATM XENON |
| 6FFI | 2018-03-07 | 2.2 | Crystal Structure of mGluR5 in complex with MMPEP at 2.2 A |
| 1CU0 | 1999-11-10 | 2.2 | T4 LYSOZYME MUTANT I78M |
| 2B6W | 2005-11-08 | 2.2 | T4 Lysozyme mutant L99A at 200 MPa |
| 3VW7 | 2012-12-12 | 2.2 | Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom |
| 5TZR | 2017-06-07 | 2.2 | GPR40 in complex with partial agonist MK-8666 |
| 151L | 1994-04-30 | 2.2 | CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME |
| 176L | 1995-07-10 | 2.2 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 5VNQ | 2017-07-26 | 2.2 | Neutron crystallographic strucutre of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature |
| 3GUM | 2009-08-25 | 2.24 | T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--p-xylene binding |
| 5VBA | 2017-07-05 | 2.27 | Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion |
| 1QTV | 1999-07-08 | 2.3 | T26E APO STRUCTURE OF T4 LYSOZYME |
| 4IAP | 2013-07-31 | 2.3 | Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae |
| 1JTN | 2002-03-20 | 2.3 | Alternative Structures of a Sequence Extended T4 Lysozyme Show that the Highly Conserved Beta-Sheet Region has weak intrinsic Folding Propensity |
| 174L | 1995-07-10 | 2.3 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 1C62 | 2000-10-04 | 2.3 | T4 LYSOZYME MUTANT C54T/C97A/F153A IN THE PRESENCE OF 8 ATM XENON |
| 196L | 1996-03-08 | 2.3 | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN 'SIZE-SWITCH' CORE-REPACKING VARIANTS OF T4 LYSOZYME |
| 3G3W | 2009-05-05 | 2.3 | Crystal structure of spin labeled T4 Lysozyme (T151R1) at 291 K |
| 4PHU | 2014-07-16 | 2.33 | Crystal structure of Human GPR40 bound to allosteric agonist TAK-875 |
| 2HUM | 2006-10-17 | 2.35 | Crystal structure of T4 Lysozyme D72C synthetic dimer |
| 4YXA | 2015-06-03 | 2.35 | Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein |
| 2B6Y | 2005-11-08 | 2.4 | T4 Lysozyme mutant L99A at ambient pressure |
| 2QAR | 2008-01-15 | 2.4 | Structure of the 2TEL crystallization module fused to T4 lysozyme with a helical linker. |
| 2B70 | 2005-11-08 | 2.4 | T4 Lysozyme mutant L99A at ambient pressure |
| 5YQR | 2018-01-31 | 2.4 | Crystal structure of the PH-like domain of Lam6 |
| 2B6Z | 2005-11-08 | 2.4 | T4 Lysozyme mutant L99A at ambient pressure |
| 1SSY | 2004-10-19 | 2.4 | Crystal structure of phage T4 lysozyme mutant G28A/I29A/G30A/C54T/C97A |
| 6K69 | 2019-08-14 | 2.4 | Application of anti-helix antibodies in protein structure determination (9213-3LRH) |
| 2RH1 | 2007-10-30 | 2.4 | High resolution crystal structure of human B2-adrenergic G protein-coupled receptor. |
| 3SB9 | 2011-09-21 | 2.45 | Cu-mediated Dimer of T4 Lysozyme R76H/R80H by Synthetic Symmetrization |
| 6A73 | 2019-07-03 | 2.45 | Complex structure of CSN2 with IP6 |
| 3SB5 | 2011-09-21 | 2.46 | Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization |
| 5D5A | 2016-01-13 | 2.48 | In meso in situ serial X-ray crystallography structure of the Beta2-adrenergic receptor at 100 K |
| 6M9T | 2018-12-05 | 2.5 | Crystal structure of EP3 receptor bound to misoprostol-FA |
| 1QS5 | 1999-07-02 | 2.5 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 5GLI | 2016-09-07 | 2.5 | Human endothelin receptor type-B in the ligand-free form |
| 189L | 1995-07-31 | 2.5 | ENHANCEMENT OF PROTEIN STABILITY BY THE COMBINATION OF POINT MUTATIONS IN T4 LYSOZYME IS ADDITIVE |
| 262L | 1999-05-24 | 2.5 | STRUCTURAL CHARACTERISATION OF AN ENGINEERED TANDEM REPEAT CONTRASTS THE IMPORTANCE OF CONTEXT AND SEQUENCE IN PROTEIN FOLDING |
| 231L | 1998-01-14 | 2.5 | T4 LYSOZYME MUTANT M106K |
| 3ODU | 2010-10-27 | 2.5 | The 2.5 A structure of the CXCR4 chemokine receptor in complex with small molecule antagonist IT1t |
| 1OYU | 2003-07-08 | 2.5 | Long-Distance conformational changes in a protein engineered by modulated sequence duplication |
| 171L | 1995-07-10 | 2.5 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 1QTC | 1999-07-22 | 2.5 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 261L | 1999-05-24 | 2.5 | STRUCTURAL CHARACTERISATION OF AN ENGINEERED TANDEM REPEAT CONTRASTS THE IMPORTANCE OF CONTEXT AND SEQUENCE IN PROTEIN FOLDING |
| 1QTD | 1999-07-22 | 2.5 | THE INTRODUCTION OF STRAIN AND ITS EFFECTS ON THE STRUCTURE AND STABILITY OF T4 LYSOZYME |
| 177L | 1995-07-10 | 2.5 | Protein flexibility and adaptability seen in 25 crystal forms of T4 LYSOZYME |
| 5EE7 | 2016-04-20 | 2.5 | Crystal structure of the human glucagon receptor (GCGR) in complex with the antagonist MK-0893 |
| 1C68 | 2000-10-04 | 2.5 | T4 LYSOZYME MUTANT C54T/C97A/L121A/L133A IN THE PRESENCE OF 8 ATM XENON |
| 1P5C | 2004-05-04 | 2.5 | Circular permutation of Helix A in T4 lysozyme |
| 2QB0 | 2008-10-14 | 2.56 | Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. |
| 4ARJ | 2012-05-09 | 2.59 | Crystal structure of a pesticin (translocation and receptor binding domain) from Y. pestis and T4-lysozyme chimera |
| 4XES | 2015-07-29 | 2.6 | Structure of active-like neurotensin receptor |
| 5CGD | 2015-08-12 | 2.6 | Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator 3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile - (HTL14242) |
| 5EWX | 2016-03-30 | 2.6 | Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS |
| 149L | 1994-04-30 | 2.6 | CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME |
| 3EML | 2008-10-14 | 2.6 | The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385. |
| 4OO9 | 2014-07-02 | 2.6 | Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant |
| 251L | 1998-03-18 | 2.6 | THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT |
| 1JQU | 2002-03-06 | 2.6 | Are Carboxy Terminii of Helices Coded by the Local Sequence or by Tertiary Structure Contacts |
| 170L | 1995-07-10 | 2.6 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 5WF5 | 2018-02-21 | 2.6 | Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution |
| 4EXM | 2012-06-20 | 2.6 | The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme |
| 5DSG | 2016-03-16 | 2.6 | Structure of the M4 muscarinic acetylcholine receptor (M4-mT4L) bound to tiotropium |
| 6FFH | 2018-03-07 | 2.65 | Crystal Structure of mGluR5 in complex with Fenobam at 2.65 A |
| 3SB8 | 2011-09-21 | 2.65 | Cu-mediated Dimer of T4 Lysozyme D61H/K65H by Synthetic Symmetrization |
| 5JEA | 2016-07-13 | 2.65 | Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA |
| 3SB6 | 2011-09-21 | 2.7 | Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization |
| 3SB7 | 2011-09-21 | 2.7 | Cu-mediated Trimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization |
| 1T97 | 2004-08-17 | 2.7 | Use of sequence duplication to engineer a ligand-triggered long-distance molecular switch in T4 Lysozyme |
| 5CXV | 2016-03-09 | 2.7 | Structure of the human M1 muscarinic acetylcholine receptor bound to antagonist Tiotropium |
| 209L | 1996-12-23 | 2.7 | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME |
| 5VEW | 2017-05-24 | 2.7 | Structure of the human GLP-1 receptor complex with PF-06372222 |
| 5X7D | 2017-08-16 | 2.7 | Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist |
| 6J20 | 2019-03-06 | 2.7 | Crystal structure of the human NK1 substance P receptor |
| 6K1Q | 2019-07-17 | 2.7 | Human endothelin receptor type-B in complex with inverse agonist IRL2500 |
| 6A9J | 2019-03-20 | 2.7 | Crystal structure of the PE-bound N-terminal domain of Atg2 |
| 5ZBQ | 2018-04-25 | 2.7 | The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299 |
| 3QAK | 2011-03-09 | 2.71 | Agonist bound structure of the human adenosine A2a receptor |
| 178L | 1995-07-10 | 2.71 | Protein flexibility and adaptability seen in 25 crystal forms of T4 LYSOZYME |
| 6D27 | 2018-10-03 | 2.74 | Crystal structure of the prostaglandin D2 receptor CRTH2 with CAY10471 |
| 3SBA | 2011-09-21 | 2.75 | Zn-mediated Hexamer of T4 Lysozyme R76H/R80H by Synthetic Symmetrization |
| 5KW2 | 2018-05-02 | 2.76 | The extra-helical binding site of GPR40 and the structural basis for allosteric agonism and incretin stimulation |
| 4LDE | 2013-09-25 | 2.79 | Structure of beta2 adrenoceptor bound to BI167107 and an engineered nanobody |
| 5GLH | 2016-09-07 | 2.8 | Human endothelin receptor type-B in complex with ET-1 |
| 6KK1 | 2019-11-13 | 2.8 | Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain |
| 5NDD | 2017-05-03 | 2.8 | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ8838 at 2.8 angstrom resolution |
| 6KJV | 2019-11-13 | 2.8 | Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain |
| 3V2Y | 2012-02-15 | 2.8 | Crystal Structure of a Lipid G protein-Coupled Receptor at 2.80A |
| 5EUT | 2015-12-23 | 2.8 | Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state |
| 4DKL | 2012-03-21 | 2.8 | Crystal structure of the mu-opioid receptor bound to a morphinan antagonist |
| 6D26 | 2018-10-03 | 2.8 | Crystal structure of the prostaglandin D2 receptor CRTH2 with fevipiprant |
| 3D4S | 2008-06-17 | 2.8 | Cholesterol bound form of human beta2 adrenergic receptor. |
| 104L | 1993-10-31 | 2.8 | HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME |
| 4GRV | 2012-10-17 | 2.8 | The crystal structure of the neurotensin receptor NTS1 in complex with neurotensin (8-13) |
| 5T1A | 2016-12-14 | 2.81 | Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists |
| 3NY9 | 2010-08-11 | 2.84 | Crystal structure of the human beta2 adrenergic receptor in complex with a novel inverse agonist |
| 3NY8 | 2010-08-11 | 2.84 | Crystal structure of the human beta2 adrenergic receptor in complex with the inverse agonist ICI 118,551 |
| 6CM4 | 2018-03-14 | 2.87 | Structure of the D2 Dopamine Receptor Bound to the Atypical Antipsychotic Drug Risperidone |
| 3PBL | 2010-11-03 | 2.89 | Structure of the human dopamine D3 receptor in complex with eticlopride |
| 4N9N | 2014-12-03 | 2.9 | Crystal Structure of Saccharomyces cerevisiae Upc2 Transcription Factor fused with T4 Lysozyme |
| 5ZKQ | 2018-06-20 | 2.9 | Crystal structure of the human platelet-activating factor receptor in complex with ABT-491 |
| 168L | 1995-07-10 | 2.9 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 5WF6 | 2018-02-21 | 2.9 | Agonist bound human A2a adenosine receptor with S91A mutation at 2.90 A resolution |
| 4XEE | 2015-07-29 | 2.9 | Structure of active-like neurotensin receptor |
| 4DJH | 2012-03-21 | 2.9 | Structure of the human kappa opioid receptor in complex with JDTic |
| 3OE0 | 2010-10-27 | 2.9 | Crystal structure of the CXCR4 chemokine receptor in complex with a cyclic peptide antagonist CVX15 |
| 6QAJ | 2019-07-24 | 2.9 | Structure of the tripartite motif of KAP1/TRIM28 |
| 6MXT | 2018-11-14 | 2.96 | Crystal structure of human beta2 adrenergic receptor bound to salmeterol and Nb71 |
| 4K5Y | 2013-07-17 | 2.98 | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395 |
| 5VEX | 2017-05-17 | 3.0 | Structure of the human GLP-1 receptor complex with NNC0640 |
| 5ZBH | 2018-04-25 | 3.0 | The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885 |
| 3JR6 | 2009-10-20 | 3.0 | Sequential reorganization of beta-sheet topology by insertion of a single strand |
| 2B7X | 2006-08-01 | 3.0 | Sequential reorganization of beta-sheet topology by insertion of a single strand |
| 5YQZ | 2018-01-17 | 3.0 | Structure of the glucagon receptor in complex with a glucagon analogue |
| 3UON | 2012-02-01 | 3.0 | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist |
| 5XEZ | 2017-05-24 | 3.0 | Structure of the Full-length glucagon class B G protein-coupled receptor |
| 169L | 1995-07-10 | 3.0 | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME |
| 5W0P | 2017-08-09 | 3.01 | Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser |
| 5CGC | 2015-08-12 | 3.1 | Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator 3-chloro-4-fluoro-5-[6-(1H-pyrazol-1-yl)pyrimidin-4-yl]benzonitrile |
| 3OE9 | 2010-10-27 | 3.1 | Crystal structure of the chemokine CXCR4 receptor in complex with a small molecule antagonist IT1t in P1 spacegroup |
| 5ZHP | 2018-11-28 | 3.1 | M3 muscarinic acetylcholine receptor in complex with a selective antagonist |
| 4LDL | 2013-09-25 | 3.1 | Structure of beta2 adrenoceptor bound to hydroxybenzylisoproterenol and an engineered nanobody |
| 3RZE | 2011-06-15 | 3.1 | Structure of the human histamine H1 receptor in complex with doxepin |
| 3OE8 | 2010-10-27 | 3.1 | Crystal structure of the CXCR4 chemokine receptor in complex with a small molecule antagonist IT1t in P1 spacegroup |
| 4RWS | 2015-02-11 | 3.1 | Crystal structure of CXCR4 and viral chemokine antagonist vMIP-II complex (PSI Community Target) |
| 6KK7 | 2019-11-13 | 3.1 | Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain |
| 3NYA | 2010-08-11 | 3.16 | Crystal structure of the human beta2 adrenergic receptor in complex with the neutral antagonist alprenolol |
| 5XF1 | 2017-05-24 | 3.19 | Structure of the Full-length glucagon class B G protein-coupled receptor |
| 5XSZ | 2017-08-16 | 3.2 | Crystal structure of zebrafish lysophosphatidic acid receptor LPA6 |
| 4TN3 | 2014-07-16 | 3.2 | Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha |
| 3OE6 | 2010-10-27 | 3.2 | Crystal structure of the CXCR4 chemokine receptor in complex with a small molecule antagonist IT1t in I222 spacegroup |
| 6J21 | 2019-03-06 | 3.2 | Crystal structure of the human NK1 substance P receptor |
| 5JQH | 2016-07-13 | 3.2 | Structure of beta2 adrenoceptor bound to carazolol and inactive-state stabilizing nanobody, Nb60 |
| 3SN6 | 2011-07-20 | 3.2 | Crystal structure of the beta2 adrenergic receptor-Gs protein complex |
| 4LDO | 2013-09-25 | 3.2 | Structure of beta2 adrenoceptor bound to adrenaline and an engineered nanobody |
| 6A9E | 2019-03-20 | 3.2 | Crystal structure of the N-terminal domain of Atg2 |
| 5D6L | 2016-08-17 | 3.2 | beta2AR-T4L - CIM |
| 5TZY | 2017-06-07 | 3.22 | GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666 |
| 4ZWJ | 2015-07-29 | 3.3 | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser |
| 5T04 | 2016-12-21 | 3.3 | STRUCTURE OF CONSTITUTIVELY ACTIVE NEUROTENSIN RECEPTOR |
| 4QKX | 2014-07-23 | 3.3 | Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody |
| 3V2W | 2012-02-15 | 3.35 | Crystal Structure of a Lipid G protein-Coupled Receptor at 3.35A |
| 4EJ4 | 2012-05-16 | 3.4 | Structure of the delta opioid receptor bound to naltrindole |
| 4DAJ | 2012-02-22 | 3.4 | Structure of the M3 Muscarinic Acetylcholine Receptor |
| 3P0G | 2011-01-19 | 3.5 | Structure of a nanobody-stabilized active state of the beta2 adrenoceptor |
| 3PDS | 2011-01-12 | 3.5 | Irreversible Agonist-Beta2 Adrenoceptor Complex |
| 5B2G | 2016-10-05 | 3.5 | Crystal structure of human claudin-4 in complex with C-terminal fragment of Clostridium perfringens enterotoxin |
| 4W8F | 2014-11-12 | 3.54 | Crystal structure of the dynein motor domain in the AMPPNP-bound state |
| 4U14 | 2014-11-26 | 3.57 | Structure of the M3 muscarinic acetylcholine receptor bound to the antagonist tiotropium crystallized with disulfide-stabilized T4 lysozyme (dsT4L) |
| 5NDZ | 2017-05-03 | 3.6 | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ3451 at 3.6 angstrom resolution |
| 5XPR | 2017-08-16 | 3.6 | Human endothelin receptor type-B in complex with antagonist bosentan |
| 5D5B | 2016-01-13 | 3.8 | In meso X-ray crystallography structure of the Beta2-adrenergic receptor at 100 K |
| 4GBR | 2012-10-24 | 3.99 | N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor |
| 4HTT | 2013-05-01 | 6.8 | Crystal Structure of Twin Arginine Translocase Receptor- TatC in DDM |
| 5DGY | 2016-03-23 | 7.7 | Crystal structure of rhodopsin bound to visual arrestin |
Relevant UniProtKB Entries
| Percent Identity | Matching Chains | Protein | Accession | Entry Name |
|---|---|---|---|---|
| 100.0 | Endolysin | P00720 | ENLYS_BPT4 |