A study on the conformation and conformational stability of ribonuclease A and its peptic derivative, des-(121-124)-ribonuclease.
Abstract
Study holds ProTherm entries: 7310 Extra Details: enzymic activity; gaussian parameters;,conformational free energies of unfolding; biosynthesis
Submission Details
ID: 25ueLyWL3
Submitter: Connie Wang
Submission Date: April 24, 2018, 8:33 p.m.
Version: 1
Publication Details
Puett D,Biochemistry (1972) A study on the conformation and conformational stability of ribonuclease A and its peptic derivative, des-(121-124)-ribonuclease. PMID:4554499Additional Information
Study Summary
| Number of data points | 1 |
| Proteins | Ribonuclease pancreatic ; Ribonuclease pancreatic |
| Unique complexes | 1 |
| Assays/Quantities/Protocols | Experimental Assay: dG_H2O |
| Libraries | Mutations for sequence KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV |
Structure view and single mutant data analysis
Study data
| Colors: | D | E | R | H | K | S | T | N | Q | A | V | I | L | M | F | Y | W | C | G | P |
|---|
Data Distribution
Studies with similar sequences (approximate matches)
Correlation with other assays (exact sequence matches)
Relevant UniProtKB Entries
| Percent Identity | Matching Chains | Protein | Accession | Entry Name |
|---|---|---|---|---|
| 100.0 | Ribonuclease pancreatic | P61824 | RNAS1_BISBI | |
| 100.0 | Ribonuclease pancreatic | P61823 | RNAS1_BOVIN | |
| 96.8 | Ribonuclease pancreatic | P67926 | RNAS1_CAPHI | |
| 96.8 | Ribonuclease pancreatic | P67927 | RNAS1_SHEEP | |
| 95.2 | Ribonuclease pancreatic | P00657 | RNAS1_BUBBU | |
| 96.0 | Ribonuclease pancreatic | P07847 | RNAS1_AEPME | |
| 93.5 | Ribonuclease pancreatic | P07848 | RNAS1_EUDTH | |
| 95.2 | Ribonuclease pancreatic | P00660 | RNAS1_CONTA | |
| 92.7 | Ribonuclease pancreatic | P00668 | RNAS1_ANTAM | |
| 90.3 | Ribonuclease pancreatic | P00662 | RNAS1_GIRCA | |
| 96.0 | Ribonuclease pancreatic | Q29606 | RNAS1_ORYLE |