∆∆G (relative to alanine)

Stability/Folding

Gibbs Free Energy of Folding/Unfolding (ΔG)

kcal/mol

Circular Dichroism (CD) , Thermal Denaturation

321 K

None

∆∆G values for beta-sheet formation at an edge position relative to alanine. ∆G values for unfolding at 321 K are determined using data from CD thermal unfolding measurements using the Gibbs-Helmholtz equation as described in Minor DL Jr;Kim PS,Nature (1994) Measurement of the beta-sheet-forming propensities of amino acids. (study id=53)